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Items: 1 to 20 of 102

1.

Fructose impairs glucose-induced hepatic triglyceride synthesis.

Huang D, Dhawan T, Young S, Yong WH, Boros LG, Heaney AP.

Lipids Health Dis. 2011 Jan 24;10:20. doi: 10.1186/1476-511X-10-20.

2.

Spironolactone improves glucose and lipid metabolism by ameliorating hepatic steatosis and inflammation and suppressing enhanced gluconeogenesis induced by high-fat and high-fructose diet.

Wada T, Kenmochi H, Miyashita Y, Sasaki M, Ojima M, Sasahara M, Koya D, Tsuneki H, Sasaoka T.

Endocrinology. 2010 May;151(5):2040-9. doi: 10.1210/en.2009-0869. Epub 2010 Mar 8.

PMID:
20211973
3.

Glucose transporter 8 (GLUT8) mediates fructose-induced de novo lipogenesis and macrosteatosis.

Debosch BJ, Chen Z, Saben JL, Finck BN, Moley KH.

J Biol Chem. 2014 Apr 18;289(16):10989-98. doi: 10.1074/jbc.M113.527002. Epub 2014 Feb 11.

4.

Modulation of hepatic sterol regulatory element-binding protein-1c-mediated gene expression contributes to Salacia oblonga root-elicited improvement of fructose-induced fatty liver in rats.

Liu L, Yang M, Lin X, Li Y, Liu C, Yang Y, Yamahara J, Wang J, Li Y.

J Ethnopharmacol. 2013 Dec 12;150(3):1045-52. doi: 10.1016/j.jep.2013.10.020. Epub 2013 Oct 21.

PMID:
24157375
5.

Dietary lipids do not contribute to the higher hepatic triglyceride levels of fructose- compared to glucose-fed mice.

Nunes PM, Wright AJ, Veltien A, van Asten JJ, Tack CJ, Jones JG, Heerschap A.

FASEB J. 2014 May;28(5):1988-97. doi: 10.1096/fj.13-241208. Epub 2014 Feb 5.

6.

Comparative effects of fructose and glucose on lipogenic gene expression and intermediary metabolism in HepG2 liver cells.

Hirahatake KM, Meissen JK, Fiehn O, Adams SH.

PLoS One. 2011;6(11):e26583. doi: 10.1371/journal.pone.0026583. Epub 2011 Nov 11.

7.

Fructose supplementation worsens the deleterious effects of short-term high-fat feeding on hepatic steatosis and lipid metabolism in adult rats.

Crescenzo R, Bianco F, Coppola P, Mazzoli A, Tussellino M, Carotenuto R, Liverini G, Iossa S.

Exp Physiol. 2014 Sep;99(9):1203-13. doi: 10.1113/expphysiol.2014.079632. Epub 2014 Jun 27.

9.

Toll-like receptor 4 is involved in the development of fructose-induced hepatic steatosis in mice.

Spruss A, Kanuri G, Wagnerberger S, Haub S, Bischoff SC, Bergheim I.

Hepatology. 2009 Oct;50(4):1094-104. doi: 10.1002/hep.23122.

PMID:
19637282
10.

Fructose surges damage hepatic adenosyl-monophosphate-dependent kinase and lead to increased lipogenesis and hepatic insulin resistance.

Gugliucci A.

Med Hypotheses. 2016 Aug;93:87-92. doi: 10.1016/j.mehy.2016.05.026. Epub 2016 May 24.

PMID:
27372863
11.

Endoplasmic reticulum stress is involved in hepatic SREBP-1c activation and lipid accumulation in fructose-fed mice.

Zhang C, Chen X, Zhu RM, Zhang Y, Yu T, Wang H, Zhao H, Zhao M, Ji YL, Chen YH, Meng XH, Wei W, Xu DX.

Toxicol Lett. 2012 Aug 3;212(3):229-40. doi: 10.1016/j.toxlet.2012.06.002. Epub 2012 Jun 12.

PMID:
22698815
12.

Dietary fructose exacerbates hepatocellular injury when incorporated into a methionine-choline-deficient diet.

Pickens MK, Ogata H, Soon RK, Grenert JP, Maher JJ.

Liver Int. 2010 Sep;30(8):1229-39. doi: 10.1111/j.1478-3231.2010.02285.x. Epub 2010 Jun 8.

13.

Acetyl-CoA carboxylase 2-/- mutant mice are protected against fatty liver under high-fat, high-carbohydrate dietary and de novo lipogenic conditions.

Abu-Elheiga L, Wu H, Gu Z, Bressler R, Wakil SJ.

J Biol Chem. 2012 Apr 6;287(15):12578-88. doi: 10.1074/jbc.M111.309559. Epub 2012 Feb 23.

14.

Metabolic effects of dietary cholesterol in an animal model of insulin resistance and hepatic steatosis.

Basciano H, Miller AE, Naples M, Baker C, Kohen R, Xu E, Su Q, Allister EM, Wheeler MB, Adeli K.

Am J Physiol Endocrinol Metab. 2009 Aug;297(2):E462-73. doi: 10.1152/ajpendo.90764.2008. Epub 2009 Jun 9.

15.

Hepatic overexpression of hormone-sensitive lipase and adipose triglyceride lipase promotes fatty acid oxidation, stimulates direct release of free fatty acids, and ameliorates steatosis.

Reid BN, Ables GP, Otlivanchik OA, Schoiswohl G, Zechner R, Blaner WS, Goldberg IJ, Schwabe RF, Chua SC Jr, Huang LS.

J Biol Chem. 2008 May 9;283(19):13087-99. doi: 10.1074/jbc.M800533200. Epub 2008 Mar 12.

16.

Ezetimibe prevents hepatic steatosis induced by a high-fat but not a high-fructose diet.

Ushio M, Nishio Y, Sekine O, Nagai Y, Maeno Y, Ugi S, Yoshizaki T, Morino K, Kume S, Kashiwagi A, Maegawa H.

Am J Physiol Endocrinol Metab. 2013 Jul 15;305(2):E293-304. doi: 10.1152/ajpendo.00442.2012. Epub 2013 May 28.

17.

ATF4 protein deficiency protects against high fructose-induced hypertriglyceridemia in mice.

Xiao G, Zhang T, Yu S, Lee S, Calabuig-Navarro V, Yamauchi J, Ringquist S, Dong HH.

J Biol Chem. 2013 Aug 30;288(35):25350-61. doi: 10.1074/jbc.M113.470526. Epub 2013 Jul 25.

18.

Reduction of liver fructokinase expression and improved hepatic inflammation and metabolism in liquid fructose-fed rats after atorvastatin treatment.

Vilà L, Rebollo A, Ađalsteisson GS, Alegret M, Merlos M, Roglans N, Laguna JC.

Toxicol Appl Pharmacol. 2011 Feb 15;251(1):32-40. doi: 10.1016/j.taap.2010.11.011. Epub 2010 Nov 29.

PMID:
21122807
19.

Methionine restriction prevents the progression of hepatic steatosis in leptin-deficient obese mice.

Malloy VL, Perrone CE, Mattocks DA, Ables GP, Caliendo NS, Orentreich DS, Orentreich N.

Metabolism. 2013 Nov;62(11):1651-61. doi: 10.1016/j.metabol.2013.06.012. Epub 2013 Aug 5.

PMID:
23928105
20.

The role of the carbohydrate response element-binding protein in male fructose-fed rats.

Erion DM, Popov V, Hsiao JJ, Vatner D, Mitchell K, Yonemitsu S, Nagai Y, Kahn M, Gillum MP, Dong J, Murray SF, Manchem VP, Bhanot S, Cline GW, Shulman GI, Samuel VT.

Endocrinology. 2013 Jan;154(1):36-44. doi: 10.1210/en.2012-1725. Epub 2012 Nov 16.

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