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Items: 1 to 20 of 102


A proposed nomenclature for cell wall proteins of Clostridium difficile.

Fagan RP, Janoir C, Collignon A, Mastrantonio P, Poxton IR, Fairweather NF.

J Med Microbiol. 2011 Aug;60(Pt 8):1225-8. doi: 10.1099/jmm.0.028472-0. Epub 2011 Jan 20.


Cyclic diGMP regulates production of sortase substrates of Clostridium difficile and their surface exposure through ZmpI protease-mediated cleavage.

Peltier J, Shaw HA, Couchman EC, Dawson LF, Yu L, Choudhary JS, Kaever V, Wren BW, Fairweather NF.

J Biol Chem. 2015 Oct 2;290(40):24453-69. doi: 10.1074/jbc.M115.665091. Epub 2015 Aug 17.


Immunoreactive cell wall proteins of Clostridium difficile identified by human sera.

Wright A, Drudy D, Kyne L, Brown K, Fairweather NF.

J Med Microbiol. 2008 Jun;57(Pt 6):750-6. doi: 10.1099/jmm.0.47532-0.


Proteomic analysis of cell surface proteins from Clostridium difficile.

Wright A, Wait R, Begum S, Crossett B, Nagy J, Brown K, Fairweather N.

Proteomics. 2005 Jun;5(9):2443-52.


Revised nomenclature of Clostridium difficile toxins and associated genes.

Rupnik M, Dupuy B, Fairweather NF, Gerding DN, Johnson S, Just I, Lyerly DM, Popoff MR, Rood JI, Sonenshein AL, Thelestam M, Wren BW, Wilkins TD, von Eichel-Streiber C.

J Med Microbiol. 2005 Feb;54(Pt 2):113-7.


Immunomodulatory activities of surface-layer proteins obtained from epidemic and hypervirulent Clostridium difficile strains.

Bianco M, Fedele G, Quattrini A, Spigaglia P, Barbanti F, Mastrantonio P, Ausiello CM.

J Med Microbiol. 2011 Aug;60(Pt 8):1162-7. doi: 10.1099/jmm.0.029694-0. Epub 2011 Feb 24.


Structural insights into the molecular organization of the S-layer from Clostridium difficile.

Fagan RP, Albesa-Jové D, Qazi O, Svergun DI, Brown KA, Fairweather NF.

Mol Microbiol. 2009 Mar;71(5):1308-22. doi: 10.1111/j.1365-2958.2009.06603.x. Epub 2009 Jan 29.


The CWB2 Cell Wall-Anchoring Module Is Revealed by the Crystal Structures of the Clostridium difficile Cell Wall Proteins Cwp8 and Cwp6.

Usenik A, Renko M, Mihelič M, Lindič N, Borišek J, Perdih A, Pretnar G, Müller U, Turk D.

Structure. 2017 Mar 7;25(3):514-521. doi: 10.1016/j.str.2016.12.018. Epub 2017 Jan 26.


Dissecting the cell surface.

Fagan R, Fairweather N.

Methods Mol Biol. 2010;646:117-34. doi: 10.1007/978-1-60327-365-7_8.


The Clostridium difficile cell wall protein CwpV is antigenically variable between strains, but exhibits conserved aggregation-promoting function.

Reynolds CB, Emerson JE, de la Riva L, Fagan RP, Fairweather NF.

PLoS Pathog. 2011 Apr;7(4):e1002024. doi: 10.1371/journal.ppat.1002024. Epub 2011 Apr 21.


Molecular characterization of the surface layer proteins from Clostridium difficile.

Calabi E, Ward S, Wren B, Paxton T, Panico M, Morris H, Dell A, Dougan G, Fairweather N.

Mol Microbiol. 2001 Jun;40(5):1187-99.


Roles of cysteine proteases Cwp84 and Cwp13 in biogenesis of the cell wall of Clostridium difficile.

de la Riva L, Willing SE, Tate EW, Fairweather NF.

J Bacteriol. 2011 Jul;193(13):3276-85. doi: 10.1128/JB.00248-11. Epub 2011 Apr 29.


The LMW surface-layer proteins of Clostridium difficile PCR ribotypes 027 and 001 share common immunogenic properties.

Spigaglia P, Galeotti CL, Barbanti F, Scarselli M, Van Broeck J, Mastrantonio P.

J Med Microbiol. 2011 Aug;60(Pt 8):1168-73. doi: 10.1099/jmm.0.029710-0. Epub 2011 Feb 24.


Binding of Clostridium difficile surface layer proteins to gastrointestinal tissues.

Calabi E, Calabi F, Phillips AD, Fairweather NF.

Infect Immun. 2002 Oct;70(10):5770-8.


Identification and characterization of a gene cluster required for proper rod shape, cell division, and pathogenesis in Clostridium difficile.

Ransom EM, Williams KB, Weiss DS, Ellermeier CD.

J Bacteriol. 2014 Jun;196(12):2290-300. doi: 10.1128/JB.00038-14. Epub 2014 Apr 11.


A novel genetic switch controls phase variable expression of CwpV, a Clostridium difficile cell wall protein.

Emerson JE, Reynolds CB, Fagan RP, Shaw HA, Goulding D, Fairweather NF.

Mol Microbiol. 2009 Nov;74(3):541-56. doi: 10.1111/j.1365-2958.2009.06812.x. Epub 2009 Jul 28.


Recombinational switching of the Clostridium difficile S-layer and a novel glycosylation gene cluster revealed by large-scale whole-genome sequencing.

Dingle KE, Didelot X, Ansari MA, Eyre DW, Vaughan A, Griffiths D, Ip CL, Batty EM, Golubchik T, Bowden R, Jolley KA, Hood DW, Fawley WN, Walker AS, Peto TE, Wilcox MH, Crook DW.

J Infect Dis. 2013 Feb 15;207(4):675-86. doi: 10.1093/infdis/jis734. Epub 2012 Nov 29.


Genomic and expression analysis of the vanG-like gene cluster of Clostridium difficile.

Peltier J, Courtin P, El Meouche I, Catel-Ferreira M, Chapot-Chartier MP, Lemée L, Pons JL.

Microbiology. 2013 Jul;159(Pt 7):1510-20. doi: 10.1099/mic.0.065060-0. Epub 2013 May 15.


Clostridium difficile surface proteins are anchored to the cell wall using CWB2 motifs that recognise the anionic polymer PSII.

Willing SE, Candela T, Shaw HA, Seager Z, Mesnage S, Fagan RP, Fairweather NF.

Mol Microbiol. 2015 May;96(3):596-608. doi: 10.1111/mmi.12958. Epub 2015 Mar 6.


Global transcriptional control by glucose and carbon regulator CcpA in Clostridium difficile.

Antunes A, Camiade E, Monot M, Courtois E, Barbut F, Sernova NV, Rodionov DA, Martin-Verstraete I, Dupuy B.

Nucleic Acids Res. 2012 Nov;40(21):10701-18. doi: 10.1093/nar/gks864. Epub 2012 Sep 18.

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