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Coexpression of VEGF and angiopoietin-1 promotes angiogenesis and cardiomyocyte proliferation reduces apoptosis in porcine myocardial infarction (MI) heart.

Tao Z, Chen B, Tan X, Zhao Y, Wang L, Zhu T, Cao K, Yang Z, Kan YW, Su H.

Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):2064-9. doi: 10.1073/pnas.1018925108. Epub 2011 Jan 18.


Combined cord blood stem cells and gene therapy enhances angiogenesis and improves cardiac performance in mouse after acute myocardial infarction.

Chen HK, Hung HF, Shyu KG, Wang BW, Sheu JR, Liang YJ, Chang CC, Kuan P.

Eur J Clin Invest. 2005 Nov;35(11):677-86.


Coexpression of angiopoietin-1 with VEGF increases the structural integrity of the blood-brain barrier and reduces atrophy volume.

Shen F, Walker EJ, Jiang L, Degos V, Li J, Sun B, Heriyanto F, Young WL, Su H.

J Cereb Blood Flow Metab. 2011 Dec;31(12):2343-51. doi: 10.1038/jcbfm.2011.97. Epub 2011 Jul 20.


Post-infarct treatment with [Pyr(1)]apelin-13 improves myocardial function by increasing neovascularization and overexpression of angiogenic growth factors in rats.

Azizi Y, Faghihi M, Imani A, Roghani M, Zekri A, Mobasheri MB, Rastgar T, Moghimian M.

Eur J Pharmacol. 2015 Aug 15;761:101-8. doi: 10.1016/j.ejphar.2015.04.034. Epub 2015 May 1.


VEGF165 and angiopoietin-1 decreased myocardium infarct size through phosphatidylinositol-3 kinase and Bcl-2 pathways.

Zhou L, Ma W, Yang Z, Zhang F, Lu L, Ding Z, Ding B, Ha T, Gao X, Li C.

Gene Ther. 2005 Feb;12(3):196-202. Erratum in: Gene Ther. 2005 Mar;12(6):552.


Adenoviral-delivered angiopoietin-1 reduces the infarction and attenuates the progression of cardiac dysfunction in the rat model of acute myocardial infarction.

Takahashi K, Ito Y, Morikawa M, Kobune M, Huang J, Tsukamoto M, Sasaki K, Nakamura K, Dehari H, Ikeda K, Uchida H, Hirai S, Abe T, Hamada H.

Mol Ther. 2003 Oct;8(4):584-92.


Myocardial angiogenesis after chronic ghrelin treatment in a rat myocardial infarction model.

Yuan MJ, He-Huang, Hu HY, Li-Quan, Hong-Jiang, Huang CX.

Regul Pept. 2012 Nov 10;179(1-3):39-42. doi: 10.1016/j.regpep.2012.08.013. Epub 2012 Sep 7.


E2F1 suppresses cardiac neovascularization by down-regulating VEGF and PlGF expression.

Wu M, Zhou J, Cheng M, Boriboun C, Biyashev D, Wang H, Mackie A, Thorne T, Chou J, Wu Y, Chen Z, Liu Q, Yan H, Yang Y, Jie C, Tang YL, Zhao TC, Taylor RN, Kishore R, Losordo DW, Qin G.

Cardiovasc Res. 2014 Dec 1;104(3):412-22. doi: 10.1093/cvr/cvu222. Epub 2014 Oct 23.


Adeno-associated viral vector delivers cardiac-specific and hypoxia-inducible VEGF expression in ischemic mouse hearts.

Su H, Joho S, Huang Y, Barcena A, Arakawa-Hoyt J, Grossman W, Kan YW.

Proc Natl Acad Sci U S A. 2004 Nov 16;101(46):16280-5. Epub 2004 Nov 8.


Mesenchymal stem cells modified with angiopoietin-1 improve remodeling in a rat model of acute myocardial infarction.

Sun L, Cui M, Wang Z, Feng X, Mao J, Chen P, Kangtao M, Chen F, Zhou C.

Biochem Biophys Res Commun. 2007 Jun 8;357(3):779-84. Epub 2007 Apr 11.


Coadministration of angiopoietin-1 and vascular endothelial growth factor enhances collateral vascularization.

Chae JK, Kim I, Lim ST, Chung MJ, Kim WH, Kim HG, Ko JK, Koh GY.

Arterioscler Thromb Vasc Biol. 2000 Dec;20(12):2573-8.


Critical role of angiopoietins/Tie-2 in hyperglycemic exacerbation of myocardial infarction and impaired angiogenesis.

Tuo QH, Zeng H, Stinnett A, Yu H, Aschner JL, Liao DF, Chen JX.

Am J Physiol Heart Circ Physiol. 2008 Jun;294(6):H2547-57. doi: 10.1152/ajpheart.01250.2007. Epub 2008 Apr 11.


Effect of transplanted mesenchymal stem cells from rats of different ages on the improvement of heart function after acute myocardial infarction.

Wang YQ, Wang M, Zhang P, Song JJ, Li YP, Hou SH, Huang CX.

Chin Med J (Engl). 2008 Nov 20;121(22):2290-8.


Combination of VEGF(165)/Angiopoietin-1 gene and endothelial progenitor cells for therapeutic neovascularization.

Chen F, Tan Z, Dong CY, Li X, Xie Y, Wu Y, Chen X, Guo S.

Eur J Pharmacol. 2007 Jul 30;568(1-3):222-30. Epub 2007 May 10.


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