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Items: 1 to 20 of 186

1.

The HIF-1-inducible lysyl oxidase activates HIF-1 via the Akt pathway in a positive regulation loop and synergizes with HIF-1 in promoting tumor cell growth.

Pez F, Dayan F, Durivault J, Kaniewski B, Aimond G, Le Provost GS, Deux B, Clézardin P, Sommer P, Pouysségur J, Reynaud C.

Cancer Res. 2011 Mar 1;71(5):1647-57. doi: 10.1158/0008-5472.CAN-10-1516. Epub 2011 Jan 14.

2.

Hypoxia/reoxygenation: a dynamic regulator of lysyl oxidase-facilitated breast cancer migration.

Postovit LM, Abbott DE, Payne SL, Wheaton WW, Margaryan NV, Sullivan R, Jansen MK, Csiszar K, Hendrix MJ, Kirschmann DA.

J Cell Biochem. 2008 Apr 1;103(5):1369-78.

PMID:
17685448
3.

YC-1 inhibits HIF-1 expression in prostate cancer cells: contribution of Akt/NF-kappaB signaling to HIF-1alpha accumulation during hypoxia.

Sun HL, Liu YN, Huang YT, Pan SL, Huang DY, Guh JH, Lee FY, Kuo SC, Teng CM.

Oncogene. 2007 Jun 7;26(27):3941-51. Epub 2007 Jan 8.

PMID:
17213816
4.

A hypoxia-independent up-regulation of hypoxia-inducible factor-1 by AKT contributes to angiogenesis in human gastric cancer.

Lee BL, Kim WH, Jung J, Cho SJ, Park JW, Kim J, Chung HY, Chang MS, Nam SY.

Carcinogenesis. 2008 Jan;29(1):44-51. Epub 2007 Nov 4.

PMID:
17984117
6.

Hypoxia accelerates cancer invasion of hepatoma cells by upregulating MMP expression in an HIF-1alpha-independent manner.

Miyoshi A, Kitajima Y, Ide T, Ohtaka K, Nagasawa H, Uto Y, Hori H, Miyazaki K.

Int J Oncol. 2006 Dec;29(6):1533-9.

PMID:
17088993
7.

Activation of hypoxia-inducible factor 1 in human T-cell leukaemia virus type 1-infected cell lines and primary adult T-cell leukaemia cells.

Tomita M, Semenza GL, Michiels C, Matsuda T, Uchihara JN, Okudaira T, Tanaka Y, Taira N, Ohshiro K, Mori N.

Biochem J. 2007 Sep 1;406(2):317-23. Retraction in: Biochem J. 2011 Mar 15;434(3):571.

8.
9.

Prolyl hydroxylases 2 and 3 act in gliomas as protective negative feedback regulators of hypoxia-inducible factors.

Henze AT, Riedel J, Diem T, Wenner J, Flamme I, Pouyseggur J, Plate KH, Acker T.

Cancer Res. 2010 Jan 1;70(1):357-66. doi: 10.1158/0008-5472.CAN-09-1876. Epub 2009 Dec 22.

11.

Semaphorin SEMA3F affects multiple signaling pathways in lung cancer cells.

Potiron VA, Sharma G, Nasarre P, Clarhaut JA, Augustin HG, Gemmill RM, Roche J, Drabkin HA.

Cancer Res. 2007 Sep 15;67(18):8708-15.

12.

Antisense hypoxia-inducible factor 1alpha gene therapy enhances the therapeutic efficacy of doxorubicin to combat hepatocellular carcinoma.

Liu F, Wang P, Jiang X, Tan G, Qiao H, Jiang H, Krissansen GW, Sun X.

Cancer Sci. 2008 Oct;99(10):2055-61. doi: 10.1111/j.1349-7006.2008.00905.x.

13.

Effect of connective tissue growth factor on hypoxia-inducible factor 1alpha degradation and tumor angiogenesis.

Chang CC, Lin MT, Lin BR, Jeng YM, Chen ST, Chu CY, Chen RJ, Chang KJ, Yang PC, Kuo ML.

J Natl Cancer Inst. 2006 Jul 19;98(14):984-95.

PMID:
16849681
14.

The involvement of phosphoinositid 3-kinase/Akt pathway in the activation of hypoxia-inducible factor-1alpha in the developing rat brain after hypoxia-ischemia.

Li L, Qu Y, Mao M, Xiong Y, Mu D.

Brain Res. 2008 Mar 4;1197:152-8. doi: 10.1016/j.brainres.2007.12.059. Epub 2008 Jan 3.

PMID:
18241842
15.

Hypoxic condition- and high cell density-induced expression of Redd1 is regulated by activation of hypoxia-inducible factor-1alpha and Sp1 through the phosphatidylinositol 3-kinase/Akt signaling pathway.

Jin HO, An S, Lee HC, Woo SH, Seo SK, Choe TB, Yoo DH, Lee SB, Um HD, Lee SJ, Park MJ, Kim JI, Hong SI, Rhee CH, Park IC.

Cell Signal. 2007 Jul;19(7):1393-403. Epub 2007 Jan 20.

PMID:
17307335
17.

Inhibition of heat shock protein 90 impairs epidermal growth factor-mediated signaling in gastric cancer cells and reduces tumor growth and vascularization in vivo.

Lang SA, Klein D, Moser C, Gaumann A, Glockzin G, Dahlke MH, Dietmaier W, Bolder U, Schlitt HJ, Geissler EK, Stoeltzing O.

Mol Cancer Ther. 2007 Mar;6(3):1123-32.

18.

Osteopontin promotes ovarian cancer progression and cell survival and increases HIF-1alpha expression through the PI3-K/Akt pathway.

Song G, Cai QF, Mao YB, Ming YL, Bao SD, Ouyang GL.

Cancer Sci. 2008 Oct;99(10):1901-7. doi: 10.1111/j.1349-7006.2008.00911.x.

19.

Hypoxia-induced epithelial VEGF-C/VEGFR-3 upregulation in carcinoma cell lines.

Simiantonaki N, Jayasinghe C, Michel-Schmidt R, Peters K, Hermanns MI, Kirkpatrick CJ.

Int J Oncol. 2008 Mar;32(3):585-92.

PMID:
18292935
20.

Chronic systemic hypoxia promotes LNCaP prostate cancer growth in vivo.

Terraneo L, Bianciardi P, Caretti A, Ronchi R, Samaja M.

Prostate. 2010 Aug;70(11):1243-54. doi: 10.1002/pros.21160.

PMID:
20333700

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