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Items: 1 to 20 of 193


Epigenetic switch involved in activation of pioneer factor FOXA1-dependent enhancers.

Sérandour AA, Avner S, Percevault F, Demay F, Bizot M, Lucchetti-Miganeh C, Barloy-Hubler F, Brown M, Lupien M, Métivier R, Salbert G, Eeckhoute J.

Genome Res. 2011 Apr;21(4):555-65. doi: 10.1101/gr.111534.110. Epub 2011 Jan 13.


FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription.

Lupien M, Eeckhoute J, Meyer CA, Wang Q, Zhang Y, Li W, Carroll JS, Liu XS, Brown M.

Cell. 2008 Mar 21;132(6):958-70. doi: 10.1016/j.cell.2008.01.018.


Foxa1 functions as a pioneer transcription factor at transposable elements to activate Afp during differentiation of embryonic stem cells.

Taube JH, Allton K, Duncan SA, Shen L, Barton MC.

J Biol Chem. 2010 May 21;285(21):16135-44. doi: 10.1074/jbc.M109.088096. Epub 2010 Mar 26.


Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers.

Eeckhoute J, Lupien M, Meyer CA, Verzi MP, Shivdasani RA, Liu XS, Brown M.

Genome Res. 2009 Mar;19(3):372-80. doi: 10.1101/gr.084582.108. Epub 2009 Jan 7.


Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells.

Metzakopian E, Bouhali K, Alvarez-Saavedra M, Whitsett JA, Picketts DJ, Ang SL.

Development. 2015 Apr 1;142(7):1315-24. doi: 10.1242/dev.115808.


FoxA1 and glucocorticoid receptor crosstalk via histone H4K16 acetylation at a hormone regulated enhancer.

Belikov S, Holmqvist PH, Astrand C, Wrange Ö.

Exp Cell Res. 2012 Jan 1;318(1):61-74. doi: 10.1016/j.yexcr.2011.09.016. Epub 2011 Oct 6.


The chromatin Remodeler CHD8 is required for activation of progesterone receptor-dependent enhancers.

Ceballos-Chávez M, Subtil-Rodríguez A, Giannopoulou EG, Soronellas D, Vázquez-Chávez E, Vicent GP, Elemento O, Beato M, Reyes JC.

PLoS Genet. 2015 Apr 20;11(4):e1005174. doi: 10.1371/journal.pgen.1005174. eCollection 2015 Apr.


Establishment of active chromatin structure at enhancer elements by mixed-lineage leukemia 1 to initiate estrogen-dependent gene expression.

Jeong KW, Andreu-Vieyra C, You JS, Jones PA, Stallcup MR.

Nucleic Acids Res. 2014 Feb;42(4):2245-56. doi: 10.1093/nar/gkt1236. Epub 2013 Nov 27.


Conserved and non-conserved enhancers direct tissue specific transcription in ancient germ layer specific developmental control genes.

Chatterjee S, Bourque G, Lufkin T.

BMC Dev Biol. 2011 Oct 20;11:63. doi: 10.1186/1471-213X-11-63.


FoxA1 binding to the MMTV LTR modulates chromatin structure and transcription.

Holmqvist PH, Belikov S, Zaret KS, Wrange O.

Exp Cell Res. 2005 Apr 1;304(2):593-603. Epub 2004 Dec 30.


Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA.

Wang D, Garcia-Bassets I, Benner C, Li W, Su X, Zhou Y, Qiu J, Liu W, Kaikkonen MU, Ohgi KA, Glass CK, Rosenfeld MG, Fu XD.

Nature. 2011 May 15;474(7351):390-4. doi: 10.1038/nature10006.


Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.

Gao N, LeLay J, Vatamaniuk MZ, Rieck S, Friedman JR, Kaestner KH.

Genes Dev. 2008 Dec 15;22(24):3435-48. doi: 10.1101/gad.1752608.


Formation of an active tissue-specific chromatin domain initiated by epigenetic marking at the embryonic stem cell stage.

Szutorisz H, Canzonetta C, Georgiou A, Chow CM, Tora L, Dillon N.

Mol Cell Biol. 2005 Mar;25(5):1804-20.


Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity.

Schmidl C, Klug M, Boeld TJ, Andreesen R, Hoffmann P, Edinger M, Rehli M.

Genome Res. 2009 Jul;19(7):1165-74. doi: 10.1101/gr.091470.109. Epub 2009 Jun 3.


Transcription of the histone H5 gene is regulated by three differentiation-specific enhancers.

Rousseau S, Asselin M, Renaud J, Ruiz-Carrillo A.

Mol Cell Biol. 1993 Aug;13(8):4904-17.


A cell-type-specific transcriptional network required for estrogen regulation of cyclin D1 and cell cycle progression in breast cancer.

Eeckhoute J, Carroll JS, Geistlinger TR, Torres-Arzayus MI, Brown M.

Genes Dev. 2006 Sep 15;20(18):2513-26.


Hematopoietic-specific activators establish an overlapping pattern of histone acetylation and methylation within a mammalian chromatin domain.

Kiekhaefer CM, Grass JA, Johnson KD, Boyer ME, Bresnick EH.

Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14309-14. Epub 2002 Oct 11.


Differential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ChIP-seq.

Motallebipour M, Ameur A, Reddy Bysani MS, Patra K, Wallerman O, Mangion J, Barker MA, McKernan KJ, Komorowski J, Wadelius C.

Genome Biol. 2009;10(11):R129. doi: 10.1186/gb-2009-10-11-r129. Epub 2009 Nov 17.


Lysine-specific demethylase 1 has dual functions as a major regulator of androgen receptor transcriptional activity.

Cai C, He HH, Gao S, Chen S, Yu Z, Gao Y, Chen S, Chen MW, Zhang J, Ahmed M, Wang Y, Metzger E, Schüle R, Liu XS, Brown M, Balk SP.

Cell Rep. 2014 Dec 11;9(5):1618-27. doi: 10.1016/j.celrep.2014.11.008. Epub 2014 Dec 4.

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