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Items: 1 to 20 of 196

1.

Regulation of ocular angiogenesis by Notch signaling: implications in neovascular age-related macular degeneration.

Ahmad I, Balasubramanian S, Del Debbio CB, Parameswaran S, Katz AR, Toris C, Fariss RN.

Invest Ophthalmol Vis Sci. 2011 May 2;52(6):2868-78. doi: 10.1167/iovs.10-6608.

2.

VEGF receptor blockade markedly reduces retinal microglia/macrophage infiltration into laser-induced CNV.

Huang H, Parlier R, Shen JK, Lutty GA, Vinores SA.

PLoS One. 2013 Aug 20;8(8):e71808. doi: 10.1371/journal.pone.0071808. eCollection 2013.

3.

Pathogenic role of the Wnt signaling pathway activation in laser-induced choroidal neovascularization.

Hu Y, Chen Y, Lin M, Lee K, Mott RA, Ma JX.

Invest Ophthalmol Vis Sci. 2013 Jan 7;54(1):141-54. doi: 10.1167/iovs.12-10281.

4.

Novel CCR3 Antagonists Are Effective Mono- and Combination Inhibitors of Choroidal Neovascular Growth and Vascular Permeability.

Nagai N, Ju M, Izumi-Nagai K, Robbie SJ, Bainbridge JW, Gale DC, Pierre E, Krauss AH, Adamson P, Shima DT, Ng YS.

Am J Pathol. 2015 Sep;185(9):2534-49. doi: 10.1016/j.ajpath.2015.04.029. Epub 2015 Jul 16.

5.

AAV-mediated expression of vascular endothelial growth factor induces choroidal neovascularization in rat.

Wang F, Rendahl KG, Manning WC, Quiroz D, Coyne M, Miller SS.

Invest Ophthalmol Vis Sci. 2003 Feb;44(2):781-90.

PMID:
12556414
6.

Endothelial Jagged1 antagonizes Dll4 regulation of endothelial branching and promotes vascular maturation downstream of Dll4/Notch1.

Pedrosa AR, Trindade A, Fernandes AC, Carvalho C, Gigante J, Tavares AT, Diéguez-Hurtado R, Yagita H, Adams RH, Duarte A.

Arterioscler Thromb Vasc Biol. 2015 May;35(5):1134-46. doi: 10.1161/ATVBAHA.114.304741. Epub 2015 Mar 12.

7.

Influence of Dll4 via HIF-1α-VEGF signaling on the angiogenesis of choroidal neovascularization under hypoxic conditions.

Dong X, Wang YS, Dou GR, Hou HY, Shi YY, Zhang R, Ma K, Wu L, Yao LB, Cai Y, Zhang J.

PLoS One. 2011 Apr 19;6(4):e18481. doi: 10.1371/journal.pone.0018481.

8.

Semaphorin 3A blocks the formation of pathologic choroidal neovascularization induced by transforming growth factor beta.

Bai Y, Liang S, Yu W, Zhao M, Huang L, Zhao M, Li X.

Mol Vis. 2014 Sep 19;20:1258-70. eCollection 2014.

9.

Inhibition of retinal and choroidal neovascularization by a novel KDR kinase inhibitor.

Kinose F, Roscilli G, Lamartina S, Anderson KD, Bonelli F, Spence SG, Ciliberto G, Vogt TF, Holder DJ, Toniatti C, Thut CJ.

Mol Vis. 2005 May 27;11:366-73.

10.

Laser-induced choroidal neovascularization in mice attenuated by deficiency in the apelin-APJ system.

Hara C, Kasai A, Gomi F, Satooka T, Sakimoto S, Nakai K, Yoshioka Y, Yamamuro A, Maeda S, Nishida K.

Invest Ophthalmol Vis Sci. 2013 Jun 21;54(6):4321-9. doi: 10.1167/iovs.13-11611.

PMID:
23722395
11.

Topical application of a G-Quartet aptamer targeting nucleolin attenuates choroidal neovascularization in a model of age-related macular degeneration.

Leaderer D, Cashman SM, Kumar-Singh R.

Exp Eye Res. 2015 Nov;140:171-8. doi: 10.1016/j.exer.2015.09.005. Epub 2015 Sep 12.

12.

Suppression of choroidal neovascularization by vasohibin-1, a vascular endothelium-derived angiogenic inhibitor.

Wakusawa R, Abe T, Sato H, Sonoda H, Sato M, Mitsuda Y, Takakura T, Fukushima T, Onami H, Nagai N, Ishikawa Y, Nishida K, Sato Y.

Invest Ophthalmol Vis Sci. 2011 May 17;52(6):3272-80. doi: 10.1167/iovs.10-6295.

PMID:
21345982
13.

Antiangiogenic activity of aganirsen in nonhuman primate and rodent models of retinal neovascular disease after topical administration.

Cloutier F, Lawrence M, Goody R, Lamoureux S, Al-Mahmood S, Colin S, Ferry A, Conduzorgues JP, Hadri A, Cursiefen C, Udaondo P, Viaud E, Thorin E, Chemtob S.

Invest Ophthalmol Vis Sci. 2012 Mar 9;53(3):1195-203. doi: 10.1167/iovs.11-9064.

PMID:
22323484
14.

The complex interplay between ERK1/2, TGFβ/Smad, and Jagged/Notch signaling pathways in the regulation of epithelial-mesenchymal transition in retinal pigment epithelium cells.

Chen X, Xiao W, Wang W, Luo L, Ye S, Liu Y.

PLoS One. 2014 May 2;9(5):e96365. doi: 10.1371/journal.pone.0096365. eCollection 2014.

15.

Blockade of Jagged/Notch pathway abrogates transforming growth factor β2-induced epithelial-mesenchymal transition in human retinal pigment epithelium cells.

Chen X, Xiao W, Liu X, Zeng M, Luo L, Wu M, Ye S, Liu Y.

Curr Mol Med. 2014 May;14(4):523-34. Review.

PMID:
24694299
16.

Regulation of multiple angiogenic pathways by Dll4 and Notch in human umbilical vein endothelial cells.

Harrington LS, Sainson RC, Williams CK, Taylor JM, Shi W, Li JL, Harris AL.

Microvasc Res. 2008 Mar;75(2):144-54. Epub 2007 Jun 29.

PMID:
17692341
17.

Role of PI3K/Akt and MEK/ERK in mediating hypoxia-induced expression of HIF-1alpha and VEGF in laser-induced rat choroidal neovascularization.

Yang XM, Wang YS, Zhang J, Li Y, Xu JF, Zhu J, Zhao W, Chu DK, Wiedemann P.

Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1873-9. doi: 10.1167/iovs.08-2591. Epub 2008 Dec 20.

PMID:
19098317
18.

Lipopolysaccharide-induced Notch signaling activation through JNK-dependent pathway regulates inflammatory response.

Tsao PN, Wei SC, Huang MT, Lee MC, Chou HC, Chen CY, Hsieh WS.

J Biomed Sci. 2011 Aug 15;18:56. doi: 10.1186/1423-0127-18-56.

19.

The MAPK-dependent regulation of the Jagged/Notch gene expression by VEGF, bFGF or PPAR gamma mediated angiogenesis in HUVEC.

Kiec-Wilk B, Grzybowska-Galuszka J, Polus A, Pryjma J, Knapp A, Kristiansen K.

J Physiol Pharmacol. 2010 Apr;61(2):217-25.

20.

Inhibition of experimental choroidal neovascularization in mice by anti-VEGFA/VEGFR2 or non-specific siRNA.

Gu L, Chen H, Tuo J, Gao X, Chen L.

Exp Eye Res. 2010 Sep;91(3):433-9. doi: 10.1016/j.exer.2010.06.019. Epub 2010 Jul 1.

PMID:
20599960

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