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Items: 1 to 20 of 105

1.

ETV6/RUNX1-positive relapses evolve from an ancestral clone and frequently acquire deletions of genes implicated in glucocorticoid signaling.

Kuster L, Grausenburger R, Fuka G, Kaindl U, Krapf G, Inthal A, Mann G, Kauer M, Rainer J, Kofler R, Hall A, Metzler M, Meyer LH, Meyer C, Harbott J, Marschalek R, Strehl S, Haas OA, Panzer-Grümayer R.

Blood. 2011 Mar 3;117(9):2658-67. doi: 10.1182/blood-2010-03-275347. Epub 2011 Jan 11.

PMID:
21224468
2.

Genetic alterations in glucocorticoid signaling pathway components are associated with adverse prognosis in children with relapsed ETV6/RUNX1-positive acute lymphoblastic leukemia.

Grausenburger R, Bastelberger S, Eckert C, Kauer M, Stanulla M, Frech C, Bauer E, Stoiber D, von Stackelberg A, Attarbaschi A, Haas OA, Panzer-Grümayer R.

Leuk Lymphoma. 2016 May;57(5):1163-73. doi: 10.3109/10428194.2015.1088650. Epub 2015 Oct 9.

PMID:
26327566
3.

Copy number genome alterations are associated with treatment response and outcome in relapsed childhood ETV6/RUNX1-positive acute lymphoblastic leukemia.

Bokemeyer A, Eckert C, Meyr F, Koerner G, von Stackelberg A, Ullmann R, Türkmen S, Henze G, Seeger K.

Haematologica. 2014 Apr;99(4):706-14. doi: 10.3324/haematol.2012.072470. Epub 2013 Nov 15.

PMID:
24241490
4.

Excellent prognosis of late relapses of ETV6/RUNX1-positive childhood acute lymphoblastic leukemia: lessons from the FRALLE 93 protocol.

Gandemer V, Chevret S, Petit A, Vermylen C, Leblanc T, Michel G, Schmitt C, Lejars O, Schneider P, Demeocq F, Bader-Meunier B, Bernaudin F, Perel Y, Auclerc MF, Cayuela JM, Leverger G, Baruchel A; FRALLE Group.

Haematologica. 2012 Nov;97(11):1743-50. doi: 10.3324/haematol.2011.059584. Epub 2012 May 11.

PMID:
22580999
5.

Clonal origins of relapse in ETV6-RUNX1 acute lymphoblastic leukemia.

van Delft FW, Horsley S, Colman S, Anderson K, Bateman C, Kempski H, Zuna J, Eckert C, Saha V, Kearney L, Ford A, Greaves M.

Blood. 2011 Jun 9;117(23):6247-54. doi: 10.1182/blood-2010-10-314674. Epub 2011 Apr 11.

PMID:
21482711
6.

ETV6/RUNX1 fusion at diagnosis and relapse: some prognostic indications.

Martineau M, Jalali GR, Barber KE, Broadfield ZJ, Cheung KL, Lilleyman J, Moorman AV, Richards S, Robinson HM, Ross F, Harrison CJ.

Genes Chromosomes Cancer. 2005 May;43(1):54-71.

PMID:
15704129
7.

Clonal variation of the immunogenotype in relapsed ETV6/RUNX1-positive acute lymphoblastic leukemia indicates subclone formation during early stages of leukemia development.

Peham M, Konrad M, Harbott J, König M, Haas OA, Panzer-Grümayer ER.

Genes Chromosomes Cancer. 2004 Feb;39(2):156-60.

PMID:
14695996
8.

Late relapses evolve from slow-responding subclones in t(12;21)-positive acute lymphoblastic leukemia: evidence for the persistence of a preleukemic clone.

Konrad M, Metzler M, Panzer S, Ostreicher I, Peham M, Repp R, Haas OA, Gadner H, Panzer-Grumayer ER.

Blood. 2003 May 1;101(9):3635-40. Epub 2002 Dec 27.

PMID:
12506024
9.

Origins of "late" relapse in childhood acute lymphoblastic leukemia with TEL-AML1 fusion genes.

Ford AM, Fasching K, Panzer-Grümayer ER, Koenig M, Haas OA, Greaves MF.

Blood. 2001 Aug 1;98(3):558-64.

PMID:
11468150
10.

Genome-wide analysis of cytogenetic aberrations in ETV6/RUNX1-positive childhood acute lymphoblastic leukaemia.

Borst L, Wesolowska A, Joshi T, Borup R, Nielsen FC, Andersen MK, Jonsson OG, Wehner PS, Wesenberg F, Frost BM, Gupta R, Schmiegelow K.

Br J Haematol. 2012 May;157(4):476-82. doi: 10.1111/j.1365-2141.2012.09083.x. Epub 2012 Mar 7.

PMID:
22404039
11.

Acquisition of genome-wide copy number alterations in monozygotic twins with acute lymphoblastic leukemia.

Bateman CM, Colman SM, Chaplin T, Young BD, Eden TO, Bhakta M, Gratias EJ, van Wering ER, Cazzaniga G, Harrison CJ, Hain R, Ancliff P, Ford AM, Kearney L, Greaves M.

Blood. 2010 Apr 29;115(17):3553-8. doi: 10.1182/blood-2009-10-251413. Epub 2010 Jan 8.

PMID:
20061556
12.

The correlation pattern of acquired copy number changes in 164 ETV6/RUNX1-positive childhood acute lymphoblastic leukemias.

Lilljebjörn H, Soneson C, Andersson A, Heldrup J, Behrendtz M, Kawamata N, Ogawa S, Koeffler HP, Mitelman F, Johansson B, Fontes M, Fioretos T.

Hum Mol Genet. 2010 Aug 15;19(16):3150-8. doi: 10.1093/hmg/ddq224. Epub 2010 May 31.

PMID:
20513752
13.

Interphase FISH on TEL/AML1 positive acute lymphoblastic leukemia relapses--analysis of clinical relevance of additional TEL and AML1 copy number changes.

Peter A, Heiden T, Taube T, Körner G, Seeger K.

Eur J Haematol. 2009 Nov;83(5):420-32. doi: 10.1111/j.1600-0609.2009.01315.x. Epub 2009 Jul 6.

PMID:
19594616
14.

ETV6-RUNX1 fusion gene and additional genetic changes in infant leukemia: a genome-wide analysis.

Emerenciano M, Bungaro S, Cazzaniga G, Dorea MD, Coser VM, Magalhães IQ, Biondi A, Pombo-de-Oliveira MS.

Cancer Genet Cytogenet. 2009 Sep;193(2):86-92. doi: 10.1016/j.cancergencyto.2009.04.021.

PMID:
19665068
15.

TEL deletion analysis supports a novel view of relapse in childhood acute lymphoblastic leukemia.

Zuna J, Ford AM, Peham M, Patel N, Saha V, Eckert C, Köchling J, Panzer-Grümayer R, Trka J, Greaves M.

Clin Cancer Res. 2004 Aug 15;10(16):5355-60.

PMID:
15328172
16.
17.

Cytogenetic and FISH studies of a single center consecutive series of 152 childhood acute lymphoblastic leukemias.

Andreasson P, Höglund M, Békássy AN, Garwicz S, Heldrup J, Mitelman F, Johansson B.

Eur J Haematol. 2000 Jul;65(1):40-51.

PMID:
10914938
18.

A set of miRNAs that involve in the pathways of drug resistance and leukemic stem-cell differentiation is associated with the risk of relapse and glucocorticoid response in childhood ALL.

Han BW, Feng DD, Li ZG, Luo XQ, Zhang H, Li XJ, Zhang XJ, Zheng LL, Zeng CW, Lin KY, Zhang P, Xu L, Chen YQ.

Hum Mol Genet. 2011 Dec 15;20(24):4903-15. doi: 10.1093/hmg/ddr428. Epub 2011 Sep 17.

PMID:
21926415
19.

ETV6/RUNX1 rearrangement in childhood B-precursor acute lymphoblastic leukemia with normal karyotypes or without cytogenetic results.

Alvarez Y, Gaitán S, Perez A, Bastida P, Ortega JJ, Dastugue N, Robert A, Aventín A, Badell I, Guitart M, Melo M, Caballín MR, Coll MD.

Cancer Genet Cytogenet. 2004 Jul 1;152(1):77-80.

PMID:
15193447
20.

Determination of ETV6-RUNX1 genomic breakpoint by next-generation sequencing.

Jin Y, Wang X, Hu S, Tang J, Li B, Chai Y.

Cancer Med. 2016 Feb;5(2):337-51. doi: 10.1002/cam4.579. Epub 2015 Dec 29.

PMID:
26711002

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