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Items: 1 to 20 of 78


[The effect of aldosterone A on renal potassium excretion].

Winther SA, Egfjord M.

Ugeskr Laeger. 2011 Jan 10;173(2):126-9. Danish.


An SGK1 site in WNK4 regulates Na+ channel and K+ channel activity and has implications for aldosterone signaling and K+ homeostasis.

Ring AM, Leng Q, Rinehart J, Wilson FH, Kahle KT, Hebert SC, Lifton RP.

Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4025-9.


Regulation of ROMK channel and K+ homeostasis by kidney-specific WNK1 kinase.

Liu Z, Wang HR, Huang CL.

J Biol Chem. 2009 May 1;284(18):12198-206. doi: 10.1074/jbc.M806551200.


WNK1 kinase isoform switch regulates renal potassium excretion.

Wade JB, Fang L, Liu J, Li D, Yang CL, Subramanya AR, Maouyo D, Mason A, Ellison DH, Welling PA.

Proc Natl Acad Sci U S A. 2006 May 30;103(22):8558-63.


Activation of PI3-kinase stimulates endocytosis of ROMK via Akt1/SGK1-dependent phosphorylation of WNK1.

Cheng CJ, Huang CL.

J Am Soc Nephrol. 2011 Mar;22(3):460-71. doi: 10.1681/ASN.2010060681.


Mineralocorticoid effects in the kidney: correlation between alphaENaC, GILZ, and Sgk-1 mRNA expression and urinary excretion of Na+ and K+.

Muller OG, Parnova RG, Centeno G, Rossier BC, Firsov D, Horisberger JD.

J Am Soc Nephrol. 2003 May;14(5):1107-15.


Regulation and function of potassium channels in aldosterone-sensitive distal nephron.

Wang WH, Yue P, Sun P, Lin DH.

Curr Opin Nephrol Hypertens. 2010 Sep;19(5):463-70. doi: 10.1097/MNH.0b013e32833c34ec. Review.


Protein phosphatase 1 modulates the inhibitory effect of With-no-Lysine kinase 4 on ROMK channels.

Lin DH, Yue P, Rinehart J, Sun P, Wang Z, Lifton R, Wang WH.

Am J Physiol Renal Physiol. 2012 Jul 1;303(1):F110-9. doi: 10.1152/ajprenal.00676.2011.


Cell surface expression of the ROMK (Kir 1.1) channel is regulated by the aldosterone-induced kinase, SGK-1, and protein kinase A.

Yoo D, Kim BY, Campo C, Nance L, King A, Maouyo D, Welling PA.

J Biol Chem. 2003 Jun 20;278(25):23066-75.


Dietary electrolyte-driven responses in the renal WNK kinase pathway in vivo.

O'Reilly M, Marshall E, Macgillivray T, Mittal M, Xue W, Kenyon CJ, Brown RW.

J Am Soc Nephrol. 2006 Sep;17(9):2402-13.


WNK1 affects surface expression of the ROMK potassium channel independent of WNK4.

Cope G, Murthy M, Golbang AP, Hamad A, Liu CH, Cuthbert AW, O'Shaughnessy KM.

J Am Soc Nephrol. 2006 Jul;17(7):1867-74.


Epithelial Na+ channel activation and processing in mice lacking SGK1.

Fejes-Tóth G, Frindt G, Náray-Fejes-Tóth A, Palmer LG.

Am J Physiol Renal Physiol. 2008 Jun;294(6):F1298-305. doi: 10.1152/ajprenal.00579.2007.


The kidney-specific WNK1 isoform is induced by aldosterone and stimulates epithelial sodium channel-mediated Na+ transport.

Náray-Fejes-Tóth A, Snyder PM, Fejes-Tóth G.

Proc Natl Acad Sci U S A. 2004 Dec 14;101(50):17434-9.


Molecular pathogenesis of pseudohypoaldosteronism type II: generation and analysis of a Wnk4(D561A/+) knockin mouse model.

Yang SS, Morimoto T, Rai T, Chiga M, Sohara E, Ohno M, Uchida K, Lin SH, Moriguchi T, Shibuya H, Kondo Y, Sasaki S, Uchida S.

Cell Metab. 2007 May;5(5):331-44.


Regulation of renal potassium secretion: molecular mechanisms.

Welling PA.

Semin Nephrol. 2013 May;33(3):215-28. doi: 10.1016/j.semnephrol.2013.04.002. Review.


Antagonistic regulation of ROMK by long and kidney-specific WNK1 isoforms.

Lazrak A, Liu Z, Huang CL.

Proc Natl Acad Sci U S A. 2006 Jan 31;103(5):1615-20.


Src family protein tyrosine kinase (PTK) modulates the effect of SGK1 and WNK4 on ROMK channels.

Yue P, Lin DH, Pan CY, Leng Q, Giebisch G, Lifton RP, Wang WH.

Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):15061-6. doi: 10.1073/pnas.0907855106.


The acidic motif of WNK4 is crucial for its interaction with the K channel ROMK.

Murthy M, Cope G, O'Shaughnessy KM.

Biochem Biophys Res Commun. 2008 Oct 31;375(4):651-4. doi: 10.1016/j.bbrc.2008.08.076.


Aldosterone induces rapid apical translocation of ENaC in early portion of renal collecting system: possible role of SGK.

Loffing J, Zecevic M, Féraille E, Kaissling B, Asher C, Rossier BC, Firestone GL, Pearce D, Verrey F.

Am J Physiol Renal Physiol. 2001 Apr;280(4):F675-82.


Regulation of potassium (K) handling in the renal collecting duct.

Wang WH, Giebisch G.

Pflugers Arch. 2009 May;458(1):157-68. doi: 10.1007/s00424-008-0593-3. Review.

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