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Items: 1 to 20 of 180

1.

Redox cycling and increased oxygen utilization contribute to diquat-induced oxidative stress and cytotoxicity in Chinese hamster ovary cells overexpressing NADPH-cytochrome P450 reductase.

Fussell KC, Udasin RG, Gray JP, Mishin V, Smith PJ, Heck DE, Laskin JD.

Free Radic Biol Med. 2011 Apr 1;50(7):874-82. doi: 10.1016/j.freeradbiomed.2010.12.035. Epub 2011 Jan 4.

2.

Distinct roles of cytochrome P450 reductase in mitomycin C redox cycling and cytotoxicity.

Wang Y, Gray JP, Mishin V, Heck DE, Laskin DL, Laskin JD.

Mol Cancer Ther. 2010 Jun;9(6):1852-63. doi: 10.1158/1535-7163.MCT-09-1098. Epub 2010 May 25.

3.

Role of cytochrome P450 reductase in nitrofurantoin-induced redox cycling and cytotoxicity.

Wang Y, Gray JP, Mishin V, Heck DE, Laskin DL, Laskin JD.

Free Radic Biol Med. 2008 Mar 15;44(6):1169-79. doi: 10.1016/j.freeradbiomed.2007.12.013. Epub 2007 Dec 23.

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Paraquat increases cyanide-insensitive respiration in murine lung epithelial cells by activating an NAD(P)H:paraquat oxidoreductase: identification of the enzyme as thioredoxin reductase.

Gray JP, Heck DE, Mishin V, Smith PJ, Hong JY, Thiruchelvam M, Cory-Slechta DA, Laskin DL, Laskin JD.

J Biol Chem. 2007 Mar 16;282(11):7939-49. Epub 2007 Jan 17.

7.

Reduction of paraquat and related bipyridylium compounds to free radical metabolites by rat hepatocytes.

DeGray JA, Rao DN, Mason RP.

Arch Biochem Biophys. 1991 Aug 15;289(1):145-52.

PMID:
1654843
8.

Redox cycling of resorufin catalyzed by rat liver microsomal NADPH-cytochrome P450 reductase.

Dutton DR, Reed GA, Parkinson A.

Arch Biochem Biophys. 1989 Feb 1;268(2):605-16.

PMID:
2464338
9.

Paraquat- and diquat-induced oxygen radical generation and lipid peroxidation in rat brain microsomes.

Yumino K, Kawakami I, Tamura M, Hayashi T, Nakamura M.

J Biochem. 2002 Apr;131(4):565-70.

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Redox cycling and hepatotoxicity of diquat in aging male Fischer 344 rats.

Rikans LE, Cai Y, Kosanke SD, Venkataraman PS.

Drug Metab Dispos. 1993 Jul-Aug;21(4):605-10.

PMID:
8104118
12.
13.

Effect of genetic variation on human cytochrome p450 reductase-mediated paraquat cytotoxicity.

Han JF, Wang SL, He XY, Liu CY, Hong JY.

Toxicol Sci. 2006 May;91(1):42-8. Epub 2006 Feb 22.

PMID:
16495354
15.

Bipyridylium herbicide toxicity: effects of paraquat and diquat on isolated rat hepatocytes.

Suleiman SA, Stevens JB.

J Environ Pathol Toxicol Oncol. 1987 Jan-Feb;7(3):73-84.

PMID:
3559919
16.

In cellulo monitoring of quinone reductase activity and reactive oxygen species production during the redox cycling of 1,2 and 1,4 quinones.

Cassagnes LE, Perio P, Ferry G, Moulharat N, Antoine M, Gayon R, Boutin JA, Nepveu F, Reybier K.

Free Radic Biol Med. 2015 Dec;89:126-34. doi: 10.1016/j.freeradbiomed.2015.07.150. Epub 2015 Sep 18.

PMID:
26386287
17.

In vivo oxidation of reduced nicotinamide-adenine dinucleotide phosphate by paraquat and diquat in rat lung.

Witschi H, Kacew S, Hirai KI, Côté MG.

Chem Biol Interact. 1977 Nov;19(2):143-60.

PMID:
22404
18.

Different effects of paraquat on microsomal lipid peroxidation in mouse brain, lung and liver.

Hara S, Endo T, Kuriiwa F, Kano S.

Pharmacol Toxicol. 1991 Apr;68(4):260-5.

PMID:
1907736
19.

Ascorbic acid uptake by isolated rat hepatocytes. Stimulatory effect of diquat, a redox cycling compound.

Cornu MC, Moore GA, Nakagawa Y, Moldéus P.

Biochem Pharmacol. 1993 Oct 19;46(8):1333-8.

PMID:
8240381
20.

Human recombinant cytochrome P450 enzymes display distinct hydrogen peroxide generating activities during substrate independent NADPH oxidase reactions.

Mishin V, Heck DE, Laskin DL, Laskin JD.

Toxicol Sci. 2014 Oct;141(2):344-52. doi: 10.1093/toxsci/kfu133. Epub 2014 Jul 24.

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