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Items: 1 to 20 of 144

1.

Hepatic transcriptomic responses to TCDD in dioxin-sensitive and dioxin-resistant rats during the onset of toxicity.

Boutros PC, Yao CQ, Watson JD, Wu AH, Moffat ID, Prokopec SD, Smith AB, Okey AB, Pohjanvirta R.

Toxicol Appl Pharmacol. 2011 Mar 1;251(2):119-29. doi: 10.1016/j.taap.2010.12.010. Epub 2011 Jan 5.

PMID:
21215274
2.

TCDD dysregulation of 13 AHR-target genes in rat liver.

Watson JD, Prokopec SD, Smith AB, Okey AB, Pohjanvirta R, Boutros PC.

Toxicol Appl Pharmacol. 2014 Feb 1;274(3):445-54. doi: 10.1016/j.taap.2013.12.004. Epub 2013 Dec 16.

3.

Transcriptional profiling of rat white adipose tissue response to 2,3,7,8-tetrachlorodibenzo-ρ-dioxin.

Houlahan KE, Prokopec SD, Sun RX, Moffat ID, Lindén J, Lensu S, Okey AB, Pohjanvirta R, Boutros PC.

Toxicol Appl Pharmacol. 2015 Oct 15;288(2):223-31. doi: 10.1016/j.taap.2015.07.018. Epub 2015 Jul 29.

4.

Inter-strain heterogeneity in rat hepatic transcriptomic responses to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).

Yao CQ, Prokopec SD, Watson JD, Pang R, P'ng C, Chong LC, Harding NJ, Pohjanvirta R, Okey AB, Boutros PC.

Toxicol Appl Pharmacol. 2012 Apr 15;260(2):135-45. doi: 10.1016/j.taap.2012.02.001. Epub 2012 Feb 9.

5.

Patterns of dioxin-altered mRNA expression in livers of dioxin-sensitive versus dioxin-resistant rats.

Franc MA, Moffat ID, Boutros PC, Tuomisto JT, Tuomisto J, Pohjanvirta R, Okey AB.

Arch Toxicol. 2008 Nov;82(11):809-30. doi: 10.1007/s00204-008-0303-0. Epub 2008 May 9. Erratum in: Arch Toxicol. 2008 Nov;82(11):831.

PMID:
18465118
6.

Differences in acute toxicity syndromes of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 1,2,3,4,7,8-hexachlorodibenzo-p-dioxin in rats.

Niittynen M, Simanainen U, Syrjälä P, Pohjanvirta R, Viluksela M, Tuomisto J, Tuomisto JT.

Toxicology. 2007 Jun 3;235(1-2):39-51. Epub 2007 Mar 15.

PMID:
17448584
7.
8.

Physicochemical differences in the AH receptors of the most TCDD-susceptible and the most TCDD-resistant rat strains.

Pohjanvirta R, Viluksela M, Tuomisto JT, Unkila M, Karasinska J, Franc MA, Holowenko M, Giannone JV, Harper PA, Tuomisto J, Okey AB.

Toxicol Appl Pharmacol. 1999 Feb 15;155(1):82-95.

PMID:
10036221
9.

2,3,7,8 Tetrachlorodibenzo-p-dioxin-induced RNA abundance changes identify Ackr3, Col18a1, Cyb5a and Glud1 as candidate mediators of toxicity.

Watson JD, Prokopec SD, Smith AB, Okey AB, Pohjanvirta R, Boutros PC.

Arch Toxicol. 2017 Jan;91(1):325-338. doi: 10.1007/s00204-016-1720-0. Epub 2016 Apr 30.

10.

Aryl hydrocarbon receptor (AHR)-regulated transcriptomic changes in rats sensitive or resistant to major dioxin toxicities.

Moffat ID, Boutros PC, Chen H, Okey AB, Pohjanvirta R.

BMC Genomics. 2010 Apr 26;11:263. doi: 10.1186/1471-2164-11-263.

11.

Persistent, low-dose 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: effect on aryl hydrocarbon receptor expression in a dioxin-resistance model.

Franc MA, Pohjanvirta R, Tuomisto J, Okey AB.

Toxicol Appl Pharmacol. 2001 Aug 15;175(1):43-53.

PMID:
11509025
12.

Transcriptional profiling of rat hypothalamus response to 2,3,7,8-tetrachlorodibenzo-ρ-dioxin.

Houlahan KE, Prokopec SD, Moffat ID, Lindén J, Lensu S, Okey AB, Pohjanvirta R, Boutros PC.

Toxicology. 2015 Feb 3;328:93-101. doi: 10.1016/j.tox.2014.12.016. Epub 2014 Dec 18.

13.

Effect of TCDD on mRNA expression of genes encoding bHLH/PAS proteins in rat hypothalamus.

Korkalainen M, Lindén J, Tuomisto J, Pohjanvirta R.

Toxicology. 2005 Mar 1;208(1):1-11.

PMID:
15664428
14.

Liver tumor-promoting activity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in TCDD-sensitive and TCDD-resistant rat strains.

Viluksela M, Bager Y, Tuomisto JT, Scheu G, Unkila M, Pohjanvirta R, Flodström S, Kosma VM, Mäki-Paakkanen J, Vartiainen T, Klimm C, Schramm KW, Wärngård L, Tuomisto J.

Cancer Res. 2000 Dec 15;60(24):6911-20.

15.

Quantitative characterization of changes in bone geometry, mineral density and biomechanical properties in two rat strains with different Ah-receptor structures after long-term exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Herlin M, Kalantari F, Stern N, Sand S, Larsson S, Viluksela M, Tuomisto JT, Tuomisto J, Tuukkanen J, Jämsä T, Lind PM, Håkansson H.

Toxicology. 2010 Jun 29;273(1-3):1-11. doi: 10.1016/j.tox.2010.04.006. Epub 2010 Apr 18.

PMID:
20403408
16.

In vivo up-regulation of aryl hydrocarbon receptor expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in a dioxin-resistant rat model.

Franc MA, Pohjanvirta R, Tuomisto J, Okey AB.

Biochem Pharmacol. 2001 Dec 15;62(12):1565-78.

PMID:
11755109
17.

Response of the incisor tooth to 2,3,7,8-tetrachlorodibenzo-p-dioxin in a dioxin-resistant and a dioxin-sensitive rat strain.

Kiukkonen A, Viluksela M, Sahlberg C, Alaluusua S, Tuomisto JT, Tuomisto J, Lukinmaa PL.

Toxicol Sci. 2002 Oct;69(2):482-9.

PMID:
12377997
18.

microRNAs in adult rodent liver are refractory to dioxin treatment.

Moffat ID, Boutros PC, Celius T, Lindén J, Pohjanvirta R, Okey AB.

Toxicol Sci. 2007 Oct;99(2):470-87. Epub 2007 Aug 13.

PMID:
17698510
19.

The AH receptor and a novel gene determine acute toxic responses to TCDD: segregation of the resistant alleles to different rat lines.

Tuomisto JT, Viluksela M, Pohjanvirta R, Tuomisto J.

Toxicol Appl Pharmacol. 1999 Feb 15;155(1):71-81.

PMID:
10036220
20.

Pattern of male reproductive system effects after in utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure in three differentially TCDD-sensitive rat lines.

Simanainen U, Haavisto T, Tuomisto JT, Paranko J, Toppari J, Tuomisto J, Peterson RE, Viluksela M.

Toxicol Sci. 2004 Jul;80(1):101-8. Epub 2004 Apr 14.

PMID:
15084753

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