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Items: 1 to 20 of 98

1.

Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors.

Aye IL, Waddell BJ, Mark PJ, Keelan JA.

Placenta. 2011 Feb;32(2):183-91. doi: 10.1016/j.placenta.2010.12.007. Epub 2011 Jan 3.

PMID:
21208656
2.

Oxysterols exert proinflammatory effects in placental trophoblasts via TLR4-dependent, cholesterol-sensitive activation of NF-κB.

Aye IL, Waddell BJ, Mark PJ, Keelan JA.

Mol Hum Reprod. 2012 Jul;18(7):341-53. doi: 10.1093/molehr/gas001. Epub 2012 Jan 10.

PMID:
22238372
3.

Liver X receptors mediate inhibition of hCG secretion in a human placental trophoblast cell line.

Weedon-Fekjaer MS, Duttaroy AK, Nebb HI.

Placenta. 2005 Nov;26(10):721-8. Epub 2004 Dec 9.

PMID:
16226121
4.

The influence of ligand-activated LXR on primary human trophoblasts.

Larkin JC, Sears SB, Sadovsky Y.

Placenta. 2014 Nov;35(11):919-24. doi: 10.1016/j.placenta.2014.09.002. Epub 2014 Sep 10.

5.

LXR-activating oxysterols induce the expression of inflammatory markers in endothelial cells through LXR-independent mechanisms.

Morello F, Saglio E, Noghero A, Schiavone D, Williams TA, Verhovez A, Bussolino F, Veglio F, Mulatero P.

Atherosclerosis. 2009 Nov;207(1):38-44. doi: 10.1016/j.atherosclerosis.2009.04.001. Epub 2009 Apr 11.

PMID:
19426978
6.

Endoglin (CD105) expression is regulated by the liver X receptor alpha (NR1H3) in human trophoblast cell line JAR.

Henry-Berger J, Mouzat K, Baron S, Bernabeu C, Marceau G, Saru JP, Sapin V, Lobaccaro JM, Caira F.

Biol Reprod. 2008 Jun;78(6):968-75. doi: 10.1095/biolreprod.107.066498. Epub 2008 Feb 14.

PMID:
18276933
7.

Liver X receptors alpha and beta promote myelination and remyelination in the cerebellum.

Meffre D, Shackleford G, Hichor M, Gorgievski V, Tzavara ET, Trousson A, Ghoumari AM, Deboux C, Nait Oumesmar B, Liere P, Schumacher M, Baulieu EE, Charbonnier F, Grenier J, Massaad C.

Proc Natl Acad Sci U S A. 2015 Jun 16;112(24):7587-92. doi: 10.1073/pnas.1424951112. Epub 2015 May 28.

8.

Cholesterol metabolite, 5-cholesten-3β-25-diol-3-sulfate, promotes hepatic proliferation in mice.

Zhang X, Bai Q, Kakiyama G, Xu L, Kim JK, Pandak WM Jr, Ren S.

J Steroid Biochem Mol Biol. 2012 Nov;132(3-5):262-70. doi: 10.1016/j.jsbmb.2012.06.001. Epub 2012 Jun 23.

9.

The liver X receptor (LXR) and its target gene ABCA1 are regulated upon low oxygen in human trophoblast cells: a reason for alterations in preeclampsia?

Plösch T, Gellhaus A, van Straten EM, Wolf N, Huijkman NC, Schmidt M, Dunk CE, Kuipers F, Winterhager E.

Placenta. 2010 Oct;31(10):910-8. doi: 10.1016/j.placenta.2010.07.009. Epub 2010 Aug 14.

PMID:
20709391
10.

22-Hydroxycholesterols regulate lipid metabolism differently than T0901317 in human myotubes.

Kase ET, Andersen B, Nebb HI, Rustan AC, Thoresen GH.

Biochim Biophys Acta. 2006 Dec;1761(12):1515-22. Epub 2006 Sep 20.

PMID:
17055780
11.

Liver X receptor activation inhibits osteoclastogenesis by suppressing NF-κB activity and c-Fos induction and prevents inflammatory bone loss in mice.

Kim HJ, Yoon KA, Yoon HJ, Hong JM, Lee MJ, Lee IK, Kim SY.

J Leukoc Biol. 2013 Jul;94(1):99-107. doi: 10.1189/jlb.1112601. Epub 2013 May 8.

PMID:
23657115
12.

Differential effects of the estrogen receptor agonist estradiol on toxicity induced by enzymatically-derived or autoxidation-derived oxysterols in human ARPE-19 cells.

Dasari B, Prasanthi JR, Meiers C, Singh BB, Ghribi O.

Curr Eye Res. 2013 Nov;38(11):1159-71. doi: 10.3109/02713683.2013.811257. Epub 2013 Jul 10.

13.

Oxysterol-induced soluble endoglin release and its involvement in hypertension.

Valbuena-Diez AC, Blanco FJ, Oujo B, Langa C, Gonzalez-Nuñez M, Llano E, Pendas AM, Díaz M, Castrillo A, Lopez-Novoa JM, Bernabeu C.

Circulation. 2012 Nov 27;126(22):2612-24. doi: 10.1161/CIRCULATIONAHA.112.101261. Epub 2012 Oct 30.

PMID:
23110859
15.

Fetal liver X receptor activation acutely induces lipogenesis but does not affect plasma lipid response to a high-fat diet in adult mice.

van Straten EM, van Meer H, Huijkman NC, van Dijk TH, Baller JF, Verkade HJ, Kuipers F, Plösch T.

Am J Physiol Endocrinol Metab. 2009 Nov;297(5):E1171-8. doi: 10.1152/ajpendo.00021.2009. Epub 2009 Sep 1.

16.

Regulation of bile acid, cholesterol, and fatty acid synthesis in chicken primary hepatocytes by different concentrations of T0901317, an agonist of liver X receptors.

Sato K, Kamada T.

Comp Biochem Physiol A Mol Integr Physiol. 2011 Feb;158(2):201-6. doi: 10.1016/j.cbpa.2010.10.028. Epub 2010 Nov 3.

PMID:
21056113
17.

25-hydroxycholesterol provokes oligodendrocyte cell line apoptosis and stimulates the secreted phospholipase A2 type IIA via LXR beta and PXR.

Trousson A, Bernard S, Petit PX, Liere P, Pianos A, El Hadri K, Lobaccaro JM, Ghandour MS, Raymondjean M, Schumacher M, Massaad C.

J Neurochem. 2009 May;109(4):945-58. doi: 10.1111/j.1471-4159.2009.06009.x. Epub 2009 Feb 24.

18.

Oxysterols suppress constitutive fibrinogen expression.

Xia H, Redman CM.

Thromb Haemost. 2003 Jul;90(1):43-51.

PMID:
12876624
19.

Impairment of trophoblast survival and differentiation by LXR ligands is prevented by cholesterol but not ABCA1 silencing.

Harmon CM, McGonigal S, Larkin JC.

Placenta. 2018 Sep;69:50-56. doi: 10.1016/j.placenta.2018.07.003. Epub 2018 Jul 10.

PMID:
30213484
20.

Lipids from oxidized low-density lipoprotein modulate human trophoblast invasion: involvement of nuclear liver X receptors.

Pavan L, Hermouet A, Tsatsaris V, Thérond P, Sawamura T, Evain-Brion D, Fournier T.

Endocrinology. 2004 Oct;145(10):4583-91. Epub 2004 Jul 8.

PMID:
15242983

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