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Items: 1 to 20 of 175

1.

T cell LFA-1 engagement induces HuR-dependent cytokine mRNA stabilization through a Vav-1, Rac1/2, p38MAPK and MKK3 signaling cascade.

Ramgolam VS, DeGregorio SD, Rao GK, Collinge M, Subaran SS, Markovic-Plese S, Pardi R, Bender JR.

PLoS One. 2010 Dec 29;5(12):e14450. doi: 10.1371/journal.pone.0014450.

2.

LFA-1-dependent HuR nuclear export and cytokine mRNA stabilization in T cell activation.

Wang JG, Collinge M, Ramgolam V, Ayalon O, Fan XC, Pardi R, Bender JR.

J Immunol. 2006 Feb 15;176(4):2105-13.

3.

Activation of the small GTPase Rac2 via the B cell receptor regulates B cell adhesion and immunological-synapse formation.

Arana E, Vehlow A, Harwood NE, Vigorito E, Henderson R, Turner M, Tybulewicz VL, Batista FD.

Immunity. 2008 Jan;28(1):88-99. doi: 10.1016/j.immuni.2007.12.003.

4.

Signaling through the leukocyte integrin LFA-1 in T cells induces a transient activation of Rac-1 that is regulated by Vav and PI3K/Akt-1.

Sánchez-Martín L, Sánchez-Sánchez N, Gutiérrez-López MD, Rojo AI, Vicente-Manzanares M, Pérez-Alvarez MJ, Sánchez-Mateos P, Bustelo XR, Cuadrado A, Sánchez-Madrid F, Rodríguez-Fernández JL, Cabañas C.

J Biol Chem. 2004 Apr 16;279(16):16194-205. Epub 2004 Feb 11.

5.

Phosphorylation of the LFA-1 integrin beta2-chain on Thr-758 leads to adhesion, Rac-1/Cdc42 activation, and stimulation of CD69 expression in human T cells.

Nurmi SM, Autero M, Raunio AK, Gahmberg CG, Fagerholm SC.

J Biol Chem. 2007 Jan 12;282(2):968-75. Epub 2006 Nov 15.

6.

Vav transformation requires activation of multiple GTPases and regulation of gene expression.

Palmby TR, Abe K, Karnoub AE, Der CJ.

Mol Cancer Res. 2004 Dec;2(12):702-11.

7.

The role of Rac1 in glycoprotein Ib-IX-mediated signal transduction and integrin activation.

Delaney MK, Liu J, Zheng Y, Berndt MC, Du X.

Arterioscler Thromb Vasc Biol. 2012 Nov;32(11):2761-8. doi: 10.1161/ATVBAHA.112.254920. Epub 2012 Sep 20.

8.
9.

Tyrosine phosphorylation of Vav stimulates IL-6 production in mast cells by a Rac/c-Jun N-terminal kinase-dependent pathway.

Song JS, Haleem-Smith H, Arudchandran R, Gomez J, Scott PM, Mill JF, Tan TH, Rivera J.

J Immunol. 1999 Jul 15;163(2):802-10.

10.

Rac1-MKK3-p38-MAPKAPK2 pathway promotes urokinase plasminogen activator mRNA stability in invasive breast cancer cells.

Han Q, Leng J, Bian D, Mahanivong C, Carpenter KA, Pan ZK, Han J, Huang S.

J Biol Chem. 2002 Dec 13;277(50):48379-85. Epub 2002 Oct 10.

11.

A novel Rac-dependent checkpoint in B cell development controls entry into the splenic white pulp and cell survival.

Henderson RB, Grys K, Vehlow A, de Bettignies C, Zachacz A, Henley T, Turner M, Batista F, Tybulewicz VL.

J Exp Med. 2010 Apr 12;207(4):837-53. doi: 10.1084/jem.20091489. Epub 2010 Mar 22.

12.

CD147 inhibits the nuclear factor of activated T-cells by impairing Vav1 and Rac1 downstream signaling.

Ruiz S, Castro-Castro A, Bustelo XR.

J Biol Chem. 2008 Feb 29;283(9):5554-66. Epub 2007 Dec 26.

13.

Stimulus-dependent regulation of the phagocyte NADPH oxidase by a VAV1, Rac1, and PAK1 signaling axis.

Roepstorff K, Rasmussen I, Sawada M, Cudre-Maroux C, Salmon P, Bokoch G, van Deurs B, Vilhardt F.

J Biol Chem. 2008 Mar 21;283(12):7983-93. Epub 2007 Dec 26.

14.

Activation of mitogen-activated protein kinase kinase (MKK) 3 and MKK6 by type I interferons.

Li Y, Batra S, Sassano A, Majchrzak B, Levy DE, Gaestel M, Fish EN, Davis RJ, Platanias LC.

J Biol Chem. 2005 Mar 18;280(11):10001-10. Epub 2005 Jan 11. Erratum in: J Biol Chem. 2006 Apr 14;281(15):10651.

15.

Vav and Rac activation in B cell antigen receptor endocytosis involves Vav recruitment to the adapter protein LAB.

Malhotra S, Kovats S, Zhang W, Coggeshall KM.

J Biol Chem. 2009 Dec 25;284(52):36202-12. doi: 10.1074/jbc.M109.040089. Epub 2009 Oct 26.

16.

Vav1 and Rac control chemokine-promoted T lymphocyte adhesion mediated by the integrin alpha4beta1.

García-Bernal D, Wright N, Sotillo-Mallo E, Nombela-Arrieta C, Stein JV, Bustelo XR, Teixidó J.

Mol Biol Cell. 2005 Jul;16(7):3223-35. Epub 2005 May 4.

18.

Mitogen-activated protein kinase phosphatase-1 inhibits myocardial TNF-α expression and improves cardiac function during endotoxemia.

Zhang T, Lu X, Arnold P, Liu Y, Baliga R, Huang H, Bauer JA, Liu Y, Feng Q.

Cardiovasc Res. 2012 Mar 1;93(3):471-9. doi: 10.1093/cvr/cvr346. Epub 2011 Dec 23.

19.

Gnb isoforms control a signaling pathway comprising Rac1, Plcβ2, and Plcβ3 leading to LFA-1 activation and neutrophil arrest in vivo.

Block H, Stadtmann A, Riad D, Rossaint J, Sohlbach C, Germena G, Wu D, Simon SI, Ley K, Zarbock A.

Blood. 2016 Jan 21;127(3):314-24. doi: 10.1182/blood-2015-06-651034. Epub 2015 Oct 14.

20.

The role of human antigen R, an RNA-binding protein, in mediating the stabilization of toll-like receptor 4 mRNA induced by endotoxin: a novel mechanism involved in vascular inflammation.

Lin FY, Chen YH, Lin YW, Tsai JS, Chen JW, Wang HJ, Chen YL, Li CY, Lin SJ.

Arterioscler Thromb Vasc Biol. 2006 Dec;26(12):2622-9. Epub 2006 Sep 21.

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