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Items: 1 to 20 of 92

1.

Structural basis for apoptosis inhibition by Epstein-Barr virus BHRF1.

Kvansakul M, Wei AH, Fletcher JI, Willis SN, Chen L, Roberts AW, Huang DC, Colman PM.

PLoS Pathog. 2010 Dec 23;6(12):e1001236. doi: 10.1371/journal.ppat.1001236.

2.

The Epstein-Barr virus Bcl-2 homolog, BHRF1, blocks apoptosis by binding to a limited amount of Bim.

Desbien AL, Kappler JW, Marrack P.

Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5663-8. doi: 10.1073/pnas.0901036106. Epub 2009 Mar 17.

3.

An Epstein-Barr virus anti-apoptotic protein constitutively expressed in transformed cells and implicated in burkitt lymphomagenesis: the Wp/BHRF1 link.

Kelly GL, Long HM, Stylianou J, Thomas WA, Leese A, Bell AI, Bornkamm GW, Mautner J, Rickinson AB, Rowe M.

PLoS Pathog. 2009 Mar;5(3):e1000341. doi: 10.1371/journal.ppat.1000341. Epub 2009 Mar 13.

4.

Crystallization and preliminary X-ray characterization of Epstein-Barr virus BHRF1 in complex with a benzoylurea peptidomimetic.

Caria S, Chugh S, Nhu D, Lessene G, Kvansakul M.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Dec 1;68(Pt 12):1521-4. doi: 10.1107/S1744309112043333. Epub 2012 Nov 14.

5.

Epstein-Barr virus-encoded Bcl-2 homologue functions as a survival factor in Wp-restricted Burkitt lymphoma cell line P3HR-1.

Watanabe A, Maruo S, Ito T, Ito M, Katsumura KR, Takada K.

J Virol. 2010 Mar;84(6):2893-901. doi: 10.1128/JVI.01616-09. Epub 2009 Dec 30.

6.

Combination of SAHA and bortezomib up-regulates CDKN2A and CDKN1A and induces apoptosis of Epstein-Barr virus-positive Wp-restricted Burkitt lymphoma and lymphoblastoid cell lines.

Hui KF, Leung YY, Yeung PL, Middeldorp JM, Chiang AK.

Br J Haematol. 2014 Dec;167(5):639-50. doi: 10.1111/bjh.13089. Epub 2014 Aug 25.

PMID:
25155625
7.

EBV-miR-BHRF1-2 targets PRDM1/Blimp1: potential role in EBV lymphomagenesis.

Ma J, Nie K, Redmond D, Liu Y, Elemento O, Knowles DM, Tam W.

Leukemia. 2016 Mar;30(3):594-604. doi: 10.1038/leu.2015.285. Epub 2015 Nov 4.

8.

Solution structure of the BHRF1 protein from Epstein-Barr virus, a homolog of human Bcl-2.

Huang Q, Petros AM, Virgin HW, Fesik SW, Olejniczak ET.

J Mol Biol. 2003 Oct 3;332(5):1123-30.

PMID:
14499614
9.

Comparative analysis of the expression of the Epstein-Barr virus (EBV) anti-apoptotic gene BHRF1 in nasopharyngeal carcinoma and EBV-related lymphoid diseases.

Nicholls J, Kremmer E, Meseda CA, Mackett M, Hahn P, Gulley ML, Brink A, Swinnen LJ, Greenspan J, De Souza Y, Grässer F, Sham J, Ng MH, Arrand JR.

J Med Virol. 2001 Sep;65(1):105-13.

PMID:
11505451
11.

Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death.

Henderson S, Huen D, Rowe M, Dawson C, Johnson G, Rickinson A.

Proc Natl Acad Sci U S A. 1993 Sep 15;90(18):8479-83.

12.

Herpesvirus pan encodes a functional homologue of BHRF1, the Epstein-Barr virus v-Bcl-2.

Howell M, Williams T, Hazlewood SA.

BMC Microbiol. 2005 Feb 3;5:6.

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17.

BCL-2 but not its Epstein-Barr virus-encoded homologue, BHRF1, is commonly expressed in posttransplantation lymphoproliferative disorders.

Murray PG, Swinnen LJ, Constandinou CM, Pyle JM, Carr TJ, Hardwick JM, Ambinder RF.

Blood. 1996 Jan 15;87(2):706-11.

18.

Selective efficacy of depsipeptide in a xenograft model of Epstein-Barr virus-positive lymphoproliferative disorder.

Roychowdhury S, Baiocchi RA, Vourganti S, Bhatt D, Blaser BW, Freud AG, Chou J, Chen CS, Xiao JJ, Parthun M, Chan KK, Eisenbeis CF, Ferketich AK, Grever MR, Chen CS, Caligiuri MA.

J Natl Cancer Inst. 2004 Oct 6;96(19):1447-57.

PMID:
15467034
19.

Epstein-barr virus-induced resistance to drugs that activate the mitotic spindle assembly checkpoint in Burkitt's lymphoma cells.

Leao M, Anderton E, Wade M, Meekings K, Allday MJ.

J Virol. 2007 Jan;81(1):248-60. Epub 2006 Oct 11.

20.

The ability of BHRF1 to inhibit apoptosis is dependent on stimulus and cell type.

Foghsgaard L, Jäättelä M.

J Virol. 1997 Oct;71(10):7509-17.

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