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Items: 1 to 20 of 96

1.

Chronic stress promotes lymphocyte reduction through TLR2 mediated PI3K signaling in a β-arrestin 2 dependent manner.

Li H, Chen L, Zhang Y, Lesage G, Zhang Y, Wu Y, Hanley G, Sun S, Yin D.

J Neuroimmunol. 2011 Apr;233(1-2):73-9. doi: 10.1016/j.jneuroim.2010.11.015. Epub 2010 Dec 22.

2.

β-arrestin 2-mediated immune suppression induced by chronic stress.

Li H, Smalligan DA, Xie N, Javer A, Zhang Y, Hanley G, Yin D.

Neuroimmunomodulation. 2011;18(3):142-9. doi: 10.1159/000322868. Epub 2011 Jan 11.

3.

TLR2 ligands attenuate cardiac dysfunction in polymicrobial sepsis via a phosphoinositide 3-kinase-dependent mechanism.

Ha T, Lu C, Liu L, Hua F, Hu Y, Kelley J, Singh K, Kao RL, Kalbfleisch J, Williams DL, Gao X, Li C.

Am J Physiol Heart Circ Physiol. 2010 Mar;298(3):H984-91. doi: 10.1152/ajpheart.01109.2009. Epub 2010 Jan 8.

4.

TLR2 ligands induce cardioprotection against ischaemia/reperfusion injury through a PI3K/Akt-dependent mechanism.

Ha T, Hu Y, Liu L, Lu C, McMullen JR, Kelley J, Kao RL, Williams DL, Gao X, Li C.

Cardiovasc Res. 2010 Sep 1;87(4):694-703. doi: 10.1093/cvr/cvq116. Epub 2010 Apr 26.

5.

Chronic restraint stress promotes immune suppression through toll-like receptor 4-mediated phosphoinositide 3-kinase signaling.

Zhang Y, Zhang Y, Miao J, Hanley G, Stuart C, Sun X, Chen T, Yin D.

J Neuroimmunol. 2008 Nov 15;204(1-2):13-9. doi: 10.1016/j.jneuroim.2008.08.011.

6.

Stimulatory Toll-like receptor 2 suppresses restraint stress-induced immune suppression.

Hu D, Denney J, Liang M, Javer A, Yang X, Zhu R, Yin D.

Cell Immunol. 2013 May-Jun;283(1-2):18-24. doi: 10.1016/j.cellimm.2013.05.007. Epub 2013 May 31.

7.

Morphine promotes apoptosis via TLR2, and this is negatively regulated by beta-arrestin 2.

Li Y, Sun X, Zhang Y, Huang J, Hanley G, Ferslew KE, Peng Y, Yin D.

Biochem Biophys Res Commun. 2009 Jan 23;378(4):857-61. doi: 10.1016/j.bbrc.2008.12.001. Epub 2008 Dec 9.

PMID:
19071087
8.

Peptidoglycan enhances proinflammatory cytokine expression through the TLR2 receptor, MyD88, phosphatidylinositol 3-kinase/AKT and NF-kappaB pathways in BV-2 microglia.

Lin HY, Tang CH, Chen YH, Wei IH, Chen JH, Lai CH, Lu DY.

Int Immunopharmacol. 2010 Aug;10(8):883-91. doi: 10.1016/j.intimp.2010.04.026. Epub 2010 May 5.

PMID:
20451669
9.
10.

β-Arrestin-2 deficiency attenuates abdominal aortic aneurysm formation in mice.

Trivedi DB, Loftin CD, Clark J, Myers P, DeGraff LM, Cheng J, Zeldin DC, Langenbach R.

Circ Res. 2013 Apr 26;112(9):1219-29. doi: 10.1161/CIRCRESAHA.112.280399. Epub 2013 Mar 22.

11.

Peptidoglycan enhances IL-6 production in human synovial fibroblasts via TLR2 receptor, focal adhesion kinase, Akt, and AP-1- dependent pathway.

Chiu YC, Lin CY, Chen CP, Huang KC, Tong KM, Tzeng CY, Lee TS, Hsu HC, Tang CH.

J Immunol. 2009 Aug 15;183(4):2785-92. doi: 10.4049/jimmunol.0802826. Epub 2009 Jul 27.

12.

TLR4, but not TLR2, signals autoregulatory apoptosis of cultured microglia: a critical role of IFN-beta as a decision maker.

Jung DY, Lee H, Jung BY, Ock J, Lee MS, Lee WH, Suk K.

J Immunol. 2005 May 15;174(10):6467-76.

13.

Phosphatidylinositol 3-kinase activation attenuates the TLR2-mediated macrophage proinflammatory cytokine response to Francisella tularensis live vaccine strain.

Medina EA, Morris IR, Berton MT.

J Immunol. 2010 Dec 15;185(12):7562-72. doi: 10.4049/jimmunol.0903790. Epub 2010 Nov 22.

14.

TLR2 ligand induces protection against cerebral ischemia/reperfusion injury via activation of phosphoinositide 3-kinase/Akt signaling.

Lu C, Liu L, Chen Y, Ha T, Kelley J, Schweitzer J, Kalbfleisch JH, Kao RL, Williams DL, Li C.

J Immunol. 2011 Aug 1;187(3):1458-66. doi: 10.4049/jimmunol.1003428. Epub 2011 Jun 27.

16.

An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior.

Beaulieu JM, Sotnikova TD, Marion S, Lefkowitz RJ, Gainetdinov RR, Caron MG.

Cell. 2005 Jul 29;122(2):261-73.

17.

Activation of Toll-like receptors by Burkholderia pseudomallei.

West TE, Ernst RK, Jansson-Hutson MJ, Skerrett SJ.

BMC Immunol. 2008 Aug 8;9:46. doi: 10.1186/1471-2172-9-46.

18.

A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1.

Hara MR, Kovacs JJ, Whalen EJ, Rajagopal S, Strachan RT, Grant W, Towers AJ, Williams B, Lam CM, Xiao K, Shenoy SK, Gregory SG, Ahn S, Duckett DR, Lefkowitz RJ.

Nature. 2011 Aug 21;477(7364):349-53. doi: 10.1038/nature10368.

19.

KISS1R signals independently of Gαq/11 and triggers LH secretion via the β-arrestin pathway in the male mouse.

Ahow M, Min L, Pampillo M, Nash C, Wen J, Soltis K, Carroll RS, Glidewell-Kenney CA, Mellon PL, Bhattacharya M, Tobet SA, Kaiser UB, Babwah AV.

Endocrinology. 2014 Nov;155(11):4433-46. doi: 10.1210/en.2014-1304. Epub 2014 Aug 22.

20.

Rac1 regulates peptidoglycan-induced nuclear factor-kappaB activation and cyclooxygenase-2 expression in RAW 264.7 macrophages by activating the phosphatidylinositol 3-kinase/Akt pathway.

Chen BC, Kang JC, Lu YT, Hsu MJ, Liao CC, Chiu WT, Yeh FL, Lin CH.

Mol Immunol. 2009 Mar;46(6):1179-88. doi: 10.1016/j.molimm.2008.11.006. Epub 2008 Dec 31.

PMID:
19118901

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