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Computational and experimental identification of mirtrons in Drosophila melanogaster and Caenorhabditis elegans.

Chung WJ, Agius P, Westholm JO, Chen M, Okamura K, Robine N, Leslie CS, Lai EC.

Genome Res. 2011 Feb;21(2):286-300. doi: 10.1101/gr.113050.110.


Mammalian mirtron genes.

Berezikov E, Chung WJ, Willis J, Cuppen E, Lai EC.

Mol Cell. 2007 Oct 26;28(2):328-36.


Intronic microRNA precursors that bypass Drosha processing.

Ruby JG, Jan CH, Bartel DP.

Nature. 2007 Jul 5;448(7149):83-6.


Analysis of Nearly One Thousand Mammalian Mirtrons Reveals Novel Features of Dicer Substrates.

Wen J, Ladewig E, Shenker S, Mohammed J, Lai EC.

PLoS Comput Biol. 2015 Sep 1;11(9):e1004441. doi: 10.1371/journal.pcbi.1004441.


Common and distinct patterns of terminal modifications to mirtrons and canonical microRNAs.

Westholm JO, Ladewig E, Okamura K, Robine N, Lai EC.

RNA. 2012 Feb;18(2):177-92. doi: 10.1261/rna.030627.111.


MicroRNA biogenesis via splicing and exosome-mediated trimming in Drosophila.

Flynt AS, Greimann JC, Chung WJ, Lima CD, Lai EC.

Mol Cell. 2010 Jun 25;38(6):900-7. doi: 10.1016/j.molcel.2010.06.014.


Identification of mirtrons in rice using MirtronPred: a tool for predicting plant mirtrons.

Joshi PK, Gupta D, Nandal UK, Khan Y, Mukherjee SK, Sanan-Mishra N.

Genomics. 2012 Jun;99(6):370-5. doi: 10.1016/j.ygeno.2012.04.002.


The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila.

Okamura K, Hagen JW, Duan H, Tyler DM, Lai EC.

Cell. 2007 Jul 13;130(1):89-100.


Discovery of hundreds of mirtrons in mouse and human small RNA data.

Ladewig E, Okamura K, Flynt AS, Westholm JO, Lai EC.

Genome Res. 2012 Sep;22(9):1634-45. doi: 10.1101/gr.133553.111.


Computational discovery of internal micro-exons.

Volfovsky N, Haas BJ, Salzberg SL.

Genome Res. 2003 Jun;13(6A):1216-21.


Selective Suppression of the Splicing-Mediated MicroRNA Pathway by the Terminal Uridyltransferase Tailor.

Bortolamiol-Becet D, Hu F, Jee D, Wen J, Okamura K, Lin CJ, Ameres SL, Lai EC.

Mol Cell. 2015 Jul 16;59(2):217-28. doi: 10.1016/j.molcel.2015.05.034.


Mirtrons: microRNA biogenesis via splicing.

Westholm JO, Lai EC.

Biochimie. 2011 Nov;93(11):1897-904. doi: 10.1016/j.biochi.2011.06.017. Review.


Uridylation of RNA Hairpins by Tailor Confines the Emergence of MicroRNAs in Drosophila.

Reimão-Pinto MM, Ignatova V, Burkard TR, Hung JH, Manzenreither RA, Sowemimo I, Herzog VA, Reichholf B, Fariña-Lopez S, Ameres SL.

Mol Cell. 2015 Jul 16;59(2):203-16. doi: 10.1016/j.molcel.2015.05.033.


The long and short of inverted repeat genes in animals: microRNAs, mirtrons and hairpin RNAs.

Okamura K, Chung WJ, Lai EC.

Cell Cycle. 2008 Sep 15;7(18):2840-5. Review.


Functional VEGFA knockdown with artificial 3'-tailed mirtrons defined by 5' splice site and branch point.

Kock KH, Kong KW, Hoon S, Seow Y.

Nucleic Acids Res. 2015 Jul 27;43(13):6568-78. doi: 10.1093/nar/gkv617.


Computational identification of Drosophila microRNA genes.

Lai EC, Tomancak P, Williams RW, Rubin GM.

Genome Biol. 2003;4(7):R42.


Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence.

Berezikov E, Robine N, Samsonova A, Westholm JO, Naqvi A, Hung JH, Okamura K, Dai Q, Bortolamiol-Becet D, Martin R, Zhao Y, Zamore PD, Hannon GJ, Marra MA, Weng Z, Perrimon N, Lai EC.

Genome Res. 2011 Feb;21(2):203-15. doi: 10.1101/gr.116657.110.


Comparison of complete nuclear receptor sets from the human, Caenorhabditis elegans and Drosophila genomes.

Maglich JM, Sluder A, Guan X, Shi Y, McKee DD, Carrick K, Kamdar K, Willson TM, Moore JT.

Genome Biol. 2001;2(8):RESEARCH0029.


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