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Items: 1 to 20 of 102

1.

Investigation and functional characterization of rare genetic variants in the adipose triglyceride lipase in a large healthy working population.

Coassin S, Schweiger M, Kloss-Brandstätter A, Lamina C, Haun M, Erhart G, Paulweber B, Rahman Y, Olpin S, Wolinski H, Cornaciu I, Zechner R, Zimmermann R, Kronenberg F.

PLoS Genet. 2010 Dec 9;6(12):e1001239. doi: 10.1371/journal.pgen.1001239.

2.

Dual regulation of adipose triglyceride lipase by pigment epithelium-derived factor: a novel mechanistic insight into progressive obesity.

Dai Z, Qi W, Li C, Lu J, Mao Y, Yao Y, Li L, Zhang T, Hong H, Li S, Zhou T, Yang Z, Yang X, Gao G, Cai W.

Mol Cell Endocrinol. 2013 Sep 5;377(1-2):123-34. doi: 10.1016/j.mce.2013.07.001. Epub 2013 Jul 10.

PMID:
23850519
3.

Metabolic consequences of adipose triglyceride lipase deficiency in humans: an in vivo study in patients with neutral lipid storage disease with myopathy.

Natali A, Gastaldelli A, Camastra S, Baldi S, Quagliarini F, Minicocci I, Bruno C, Pennisi E, Arca M.

J Clin Endocrinol Metab. 2013 Sep;98(9):E1540-8. doi: 10.1210/jc.2013-1444. Epub 2013 Jul 3.

PMID:
23824421
4.

Adipose triglyceride lipase regulates lipid metabolism in dairy goat mammary epithelial cells.

Li J, Luo J, Wang H, Shi H, Zhu J, Sun Y, Yu K, Yao D.

Gene. 2015 Jan 1;554(1):125-30. doi: 10.1016/j.gene.2014.10.020. Epub 2014 Oct 11.

PMID:
25307872
5.

Neutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5.

Schweiger M, Lass A, Zimmermann R, Eichmann TO, Zechner R.

Am J Physiol Endocrinol Metab. 2009 Aug;297(2):E289-96. doi: 10.1152/ajpendo.00099.2009. Epub 2009 Apr 28. Review.

6.

Genetic mutations in adipose triglyceride lipase and myocardial up-regulation of peroxisome proliferated activated receptor-γ in patients with triglyceride deposit cardiomyovasculopathy.

Hirano K, Tanaka T, Ikeda Y, Yamaguchi S, Zaima N, Kobayashi K, Suzuki A, Sakata Y, Sakata Y, Kobayashi K, Toda T, Fukushima N, Ishibashi-Ueda H, Tavian D, Nagasaka H, Hui SP, Chiba H, Sawa Y, Hori M.

Biochem Biophys Res Commun. 2014 Jan 10;443(2):574-9. doi: 10.1016/j.bbrc.2013.12.003. Epub 2013 Dec 8.

PMID:
24332944
7.

Genetic variants in adipose triglyceride lipase influence lipid levels in familial combined hyperlipidemia.

Nanni L, Quagliarini F, Megiorni F, Montali A, Minicocci I, Campagna F, Pizzuti A, Arca M.

Atherosclerosis. 2010 Nov;213(1):206-11. doi: 10.1016/j.atherosclerosis.2010.08.055. Epub 2010 Aug 19.

PMID:
20832801
8.

The lack of the C-terminal domain of adipose triglyceride lipase causes neutral lipid storage disease through impaired interactions with lipid droplets.

Kobayashi K, Inoguchi T, Maeda Y, Nakashima N, Kuwano A, Eto E, Ueno N, Sasaki S, Sawada F, Fujii M, Matoba Y, Sumiyoshi S, Kawate H, Takayanagi R.

J Clin Endocrinol Metab. 2008 Jul;93(7):2877-84. doi: 10.1210/jc.2007-2247. Epub 2008 Apr 29.

PMID:
18445677
9.

The ATGL gene is associated with free fatty acids, triglycerides, and type 2 diabetes.

Schoenborn V, Heid IM, Vollmert C, Lingenhel A, Adams TD, Hopkins PN, Illig T, Zimmermann R, Zechner R, Hunt SC, Kronenberg F.

Diabetes. 2006 May;55(5):1270-5.

10.

The C-terminal region of human adipose triglyceride lipase affects enzyme activity and lipid droplet binding.

Schweiger M, Schoiswohl G, Lass A, Radner FP, Haemmerle G, Malli R, Graier W, Cornaciu I, Oberer M, Salvayre R, Fischer J, Zechner R, Zimmermann R.

J Biol Chem. 2008 Jun 20;283(25):17211-20. doi: 10.1074/jbc.M710566200. Epub 2008 Apr 29.

11.

Fat-reducing effects of dehydroepiandrosterone involve upregulation of ATGL and HSL expression, and stimulation of lipolysis in adipose tissue.

Karbowska J, Kochan Z.

Steroids. 2012 Nov;77(13):1359-65. doi: 10.1016/j.steroids.2012.08.002. Epub 2012 Aug 23.

PMID:
22951290
12.

Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A.

Nagy HM, Paar M, Heier C, Moustafa T, Hofer P, Haemmerle G, Lass A, Zechner R, Oberer M, Zimmermann R.

Biochim Biophys Acta. 2014 Apr 4;1841(4):588-94. doi: 10.1016/j.bbalip.2014.01.005. Epub 2014 Jan 16.

13.

Reduced expression of adipose triglyceride lipase enhances tumor necrosis factor alpha-induced intercellular adhesion molecule-1 expression in human aortic endothelial cells via protein kinase C-dependent activation of nuclear factor-kappaB.

Inoue T, Kobayashi K, Inoguchi T, Sonoda N, Fujii M, Maeda Y, Fujimura Y, Miura D, Hirano K, Takayanagi R.

J Biol Chem. 2011 Sep 16;286(37):32045-53. doi: 10.1074/jbc.M111.285650. Epub 2011 Aug 2.

14.

Cardiac oxidative stress in a mouse model of neutral lipid storage disease.

Schrammel A, Mussbacher M, Winkler S, Haemmerle G, Stessel H, Wölkart G, Zechner R, Mayer B.

Biochim Biophys Acta. 2013 Nov;1831(11):1600-8. doi: 10.1016/j.bbalip.2013.07.004. Epub 2013 Jul 15.

15.

Contribution of novel ATGL missense mutations to the clinical phenotype of NLSD-M: a strikingly low amount of lipase activity may preserve cardiac function.

Tavian D, Missaglia S, Redaelli C, Pennisi EM, Invernici G, Wessalowski R, Maiwald R, Arca M, Coleman RA.

Hum Mol Genet. 2012 Dec 15;21(24):5318-28. doi: 10.1093/hmg/dds388. Epub 2012 Sep 17.

16.

Adipose triglyceride lipase is implicated in fuel- and non-fuel-stimulated insulin secretion.

Peyot ML, Guay C, Latour MG, Lamontagne J, Lussier R, Pineda M, Ruderman NB, Haemmerle G, Zechner R, Joly E, Madiraju SR, Poitout V, Prentki M.

J Biol Chem. 2009 Jun 19;284(25):16848-59. doi: 10.1074/jbc.M109.006650. Epub 2009 Apr 22.

17.

Human adipose triglyceride lipase (PNPLA2) is not regulated by obesity and exhibits low in vitro triglyceride hydrolase activity.

Mairal A, Langin D, Arner P, Hoffstedt J.

Diabetologia. 2006 Jul;49(7):1629-36. Epub 2006 May 10.

PMID:
16752181
18.

[Adipose triglyceride lipase regulates adipocyte lipolysis].

Xu C, Xu GH.

Sheng Li Ke Xue Jin Zhan. 2008 Jan;39(1):10-4. Review. Chinese.

PMID:
18357681
19.

Molecular characterization and association analysis of porcine adipose triglyceride lipase (PNPLA2) gene.

Dai LH, Xiong YZ, Jiang SW, Chen JF.

Mol Biol Rep. 2011 Feb;38(2):921-7. doi: 10.1007/s11033-010-0185-0. Epub 2010 May 18.

PMID:
20480242
20.

Identification of a novel phosphorylation site in adipose triglyceride lipase as a regulator of lipid droplet localization.

Xie X, Langlais P, Zhang X, Heckmann BL, Saarinen AM, Mandarino LJ, Liu J.

Am J Physiol Endocrinol Metab. 2014 Jun 15;306(12):E1449-59. doi: 10.1152/ajpendo.00663.2013. Epub 2014 May 6.

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