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Items: 1 to 20 of 107

1.

Abnormal fibrillin-1 expression and chronic oxidative stress mediate endothelial mesenchymal transition in a murine model of systemic sclerosis.

Xu H, Zaidi M, Struve J, Jones DW, Krolikowski JG, Nandedkar S, Lohr NL, Gadicherla A, Pagel PS, Csuka ME, Pritchard KA, Weihrauch D.

Am J Physiol Cell Physiol. 2011 Mar;300(3):C550-6. doi: 10.1152/ajpcell.00123.2010. Epub 2010 Dec 15.

2.

Effects of D-4F on vasodilation, oxidative stress, angiostatin, myocardial inflammation, and angiogenic potential in tight-skin mice.

Weihrauch D, Xu H, Shi Y, Wang J, Brien J, Jones DW, Kaul S, Komorowski RA, Csuka ME, Oldham KT, Pritchard KA.

Am J Physiol Heart Circ Physiol. 2007 Sep;293(3):H1432-41. Epub 2007 May 11.

3.

Mutant fibrillin 1 from tight skin mice increases extracellular matrix incorporation of microfibril-associated glycoprotein 2 and type I collagen.

Lemaire R, Farina G, Kissin E, Shipley JM, Bona C, Korn JH, Lafyatis R.

Arthritis Rheum. 2004 Mar;50(3):915-26.

4.
5.

Antagonistic effect of the matricellular signaling protein CCN3 on TGF-beta- and Wnt-mediated fibrillinogenesis in systemic sclerosis and Marfan syndrome.

Lemaire R, Farina G, Bayle J, Dimarzio M, Pendergrass SA, Milano A, Perbal B, Whitfield ML, Lafyatis R.

J Invest Dermatol. 2010 Jun;130(6):1514-23. doi: 10.1038/jid.2010.15. Epub 2010 Feb 25. Erratum in: J Invest Dermatol. 2010 Oct;130(10):2517. Perbal, Bernard [added].

6.

Increased expression of Wnt2 and SFRP4 in Tsk mouse skin: role of Wnt signaling in altered dermal fibrillin deposition and systemic sclerosis.

Bayle J, Fitch J, Jacobsen K, Kumar R, Lafyatis R, Lemaire R.

J Invest Dermatol. 2008 Apr;128(4):871-81. Epub 2007 Oct 18.

7.
8.

The Tight skin mouse: demonstration of mutant fibrillin-1 production and assembly into abnormal microfibrils.

Kielty CM, Raghunath M, Siracusa LD, Sherratt MJ, Peters R, Shuttleworth CA, Jimenez SA.

J Cell Biol. 1998 Mar 9;140(5):1159-66.

9.

Fibulin-2 and fibulin-5 alterations in tsk mice associated with disorganized hypodermal elastic fibers and skin tethering.

Lemaire R, Korn JH, Schiemann WP, Lafyatis R.

J Invest Dermatol. 2004 Dec;123(6):1063-9.

10.

Spontaneous occurrence of anti-fibrillin-1 autoantibodies in tight-skin mice.

Murai C, Saito S, Kasturi KN, Bona CA.

Autoimmunity. 1998;28(3):151-5.

PMID:
9867127
11.

The tight skin mouse: an animal model of systemic sclerosis.

Pablos JL, Everett ET, Norris JS.

Clin Exp Rheumatol. 2004 Jan-Feb;22(3 Suppl 33):S81-5.

PMID:
15344604
12.

4F decreases IRF5 expression and activation in hearts of tight skin mice.

Xu H, Krolikowski JG, Jones DW, Ge ZD, Pagel PS, Pritchard KA Jr, Weihrauch D.

PLoS One. 2012;7(12):e52046. doi: 10.1371/journal.pone.0052046. Epub 2012 Dec 14.

13.

Systemic sclerosis sera affect fibrillin-1 deposition by dermal blood microvascular endothelial cells: therapeutic implications of cyclophosphamide.

Villano M, Borghini A, Manetti M, Gabbrielli E, Rossi A, Sestini P, Milia A, Nacci F, Guiducci S, Matucci-Cerinic M, Ibba-Manneschi L, Weber E.

Arthritis Res Ther. 2013 Aug 20;15(4):R90. doi: 10.1186/ar4270.

14.
15.

Abnormalities in fibrillin 1-containing microfibrils in dermal fibroblast cultures from patients with systemic sclerosis (scleroderma).

Wallis DD, Tan FK, Kielty CM, Kimball MD, Arnett FC, Milewicz DM.

Arthritis Rheum. 2001 Aug;44(8):1855-64.

16.

A tandem duplication within the fibrillin 1 gene is associated with the mouse tight skin mutation.

Siracusa LD, McGrath R, Ma Q, Moskow JJ, Manne J, Christner PJ, Buchberg AM, Jimenez SA.

Genome Res. 1996 Apr;6(4):300-13.

17.

Complex integration of matrix, oxidative stress, and apoptosis in genetic emphysema.

Podowski M, Calvi CL, Cheadle C, Tuder RM, Biswals S, Neptune ER.

Am J Pathol. 2009 Jul;175(1):84-96. doi: 10.2353/ajpath.2009.080870. Epub 2009 Jun 18.

18.

Transient repetitive exposure to low level light therapy enhances collateral blood vessel growth in the ischemic hindlimb of the tight skin mouse.

Zaidi M, Krolikowki JG, Jones DW, Pritchard KA Jr, Struve J, Nandedkar SD, Lohr NL, Pagel PS, Weihrauch D.

Photochem Photobiol. 2013 May-Jun;89(3):709-13. doi: 10.1111/php.12024. Epub 2013 Jan 7.

20.

Transforming growth factor beta induces fibroblast fibrillin-1 matrix formation.

Kissin EY, Lemaire R, Korn JH, Lafyatis R.

Arthritis Rheum. 2002 Nov;46(11):3000-9.

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