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Items: 1 to 20 of 123

1.

The canonical NF-kappaB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion.

Liu M, Sakamaki T, Casimiro MC, Willmarth NE, Quong AA, Ju X, Ojeifo J, Jiao X, Yeow WS, Katiyar S, Shirley LA, Joyce D, Lisanti MP, Albanese C, Pestell RG.

Cancer Res. 2010 Dec 15;70(24):10464-73. doi: 10.1158/0008-5472.CAN-10-0732.

3.

Nuclear factor-kappaB enhances ErbB2-induced mammary tumorigenesis and neoangiogenesis in vivo.

Liu M, Ju X, Willmarth NE, Casimiro MC, Ojeifo J, Sakamaki T, Katiyar S, Jiao X, Popov VM, Yu Z, Wu K, Joyce D, Wang C, Pestell RG.

Am J Pathol. 2009 May;174(5):1910-20. doi: 10.2353/ajpath.2009.080706. Epub 2009 Apr 6.

4.

The canonical NF-kappaB pathway is required for formation of luminal mammary neoplasias and is activated in the mammary progenitor population.

Pratt MA, Tibbo E, Robertson SJ, Jansson D, Hurst K, Perez-Iratxeta C, Lau R, Niu MY.

Oncogene. 2009 Jul 30;28(30):2710-22. doi: 10.1038/onc.2009.131. Epub 2009 Jun 1.

PMID:
19483731
5.

NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression.

Huber MA, Azoitei N, Baumann B, Grünert S, Sommer A, Pehamberger H, Kraut N, Beug H, Wirth T.

J Clin Invest. 2004 Aug;114(4):569-81.

6.

The nuclear factor kappa B (NF-kappa B): a potential therapeutic target for estrogen receptor negative breast cancers.

Biswas DK, Dai SC, Cruz A, Weiser B, Graner E, Pardee AB.

Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10386-91. Epub 2001 Aug 21.

7.

Sustained trophism of the mammary gland is sufficient to accelerate and synchronize development of ErbB2/Neu-induced tumors.

Landis MD, Seachrist DD, Abdul-Karim FW, Keri RA.

Oncogene. 2006 Jun 1;25(23):3325-34. Epub 2006 Jan 23.

8.

Targeting FACT complex suppresses mammary tumorigenesis in Her2/neu transgenic mice.

Koman IE, Commane M, Paszkiewicz G, Hoonjan B, Pal S, Safina A, Toshkov I, Purmal AA, Wang D, Liu S, Morrison C, Gudkov AV, Gurova KV.

Cancer Prev Res (Phila). 2012 Aug;5(8):1025-35. doi: 10.1158/1940-6207.CAPR-11-0529. Epub 2012 Jun 11.

9.

p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis.

Cabodi S, Tinnirello A, Di Stefano P, Bisarò B, Ambrosino E, Castellano I, Sapino A, Arisio R, Cavallo F, Forni G, Glukhova M, Silengo L, Altruda F, Turco E, Tarone G, Defilippi P.

Cancer Res. 2006 May 1;66(9):4672-80.

10.

RelB/p52 NF-kappaB complexes rescue an early delay in mammary gland development in transgenic mice with targeted superrepressor IkappaB-alpha expression and promote carcinogenesis of the mammary gland.

Demicco EG, Kavanagh KT, Romieu-Mourez R, Wang X, Shin SR, Landesman-Bollag E, Seldin DC, Sonenshein GE.

Mol Cell Biol. 2005 Nov;25(22):10136-47.

11.

NF-κB, stem cells and breast cancer: the links get stronger.

Shostak K, Chariot A.

Breast Cancer Res. 2011 Jul 26;13(4):214. doi: 10.1186/bcr2886. Review.

12.

The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling.

Brantley-Sieders DM, Zhuang G, Hicks D, Fang WB, Hwang Y, Cates JM, Coffman K, Jackson D, Bruckheimer E, Muraoka-Cook RS, Chen J.

J Clin Invest. 2008 Jan;118(1):64-78.

13.

Nuclear factor-kappaB (NF-kappaB) regulates proliferation and branching in mouse mammary epithelium.

Brantley DM, Chen CL, Muraoka RS, Bushdid PB, Bradberry JL, Kittrell F, Medina D, Matrisian LM, Kerr LD, Yull FE.

Mol Biol Cell. 2001 May;12(5):1445-55.

14.

Mammary gland specific expression of Brk/PTK6 promotes delayed involution and tumor formation associated with activation of p38 MAPK.

Lofgren KA, Ostrander JH, Housa D, Hubbard GK, Locatelli A, Bliss RL, Schwertfeger KL, Lange CA.

Breast Cancer Res. 2011 Sep 17;13(5):R89. doi: 10.1186/bcr2946.

15.

Protein kinase CK2 promotes aberrant activation of nuclear factor-kappaB, transformed phenotype, and survival of breast cancer cells.

Romieu-Mourez R, Landesman-Bollag E, Seldin DC, Sonenshein GE.

Cancer Res. 2002 Nov 15;62(22):6770-8.

16.

The role of Ink4a/Arf in ErbB2 mammary gland tumorigenesis.

D'Amico M, Wu K, Di Vizio D, Reutens AT, Stahl M, Fu M, Albanese C, Russell RG, Muller WJ, White M, Negassa A, Lee HW, DePinho RA, Pestell RG.

Cancer Res. 2003 Jun 15;63(12):3395-402.

17.

Metastasis is an early event in mouse mammary carcinomas and is associated with cells bearing stem cell markers.

Weng D, Penzner JH, Song B, Koido S, Calderwood SK, Gong J.

Breast Cancer Res. 2012 Jan 25;14(1):R18.

18.

Function of focal adhesion kinase scaffolding to mediate endophilin A2 phosphorylation promotes epithelial-mesenchymal transition and mammary cancer stem cell activities in vivo.

Fan H, Zhao X, Sun S, Luo M, Guan JL.

J Biol Chem. 2013 Feb 1;288(5):3322-33. doi: 10.1074/jbc.M112.420497. Epub 2012 Dec 19.

19.

Noncanonical TGF-β signaling during mammary tumorigenesis.

Parvani JG, Taylor MA, Schiemann WP.

J Mammary Gland Biol Neoplasia. 2011 Jun;16(2):127-46. doi: 10.1007/s10911-011-9207-3. Epub 2011 Mar 31. Review.

20.

Mammary epithelial-specific ablation of the focal adhesion kinase suppresses mammary tumorigenesis by affecting mammary cancer stem/progenitor cells.

Luo M, Fan H, Nagy T, Wei H, Wang C, Liu S, Wicha MS, Guan JL.

Cancer Res. 2009 Jan 15;69(2):466-74. doi: 10.1158/0008-5472.CAN-08-3078.

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