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Items: 1 to 20 of 94

1.

AEOL10150: a novel therapeutic for rescue treatment after toxic gas lung injury.

McGovern T, Day BJ, White CW, Powell WS, Martin JG.

Free Radic Biol Med. 2011 Mar 1;50(5):602-8. doi: 10.1016/j.freeradbiomed.2010.12.001. Epub 2010 Dec 13.

2.

Dimethylthiourea protects against chlorine induced changes in airway function in a murine model of irritant induced asthma.

McGovern TK, Powell WS, Day BJ, White CW, Govindaraju K, Karmouty-Quintana H, Lavoie N, Tan JJ, Martin JG.

Respir Res. 2010 Oct 6;11:138. doi: 10.1186/1465-9921-11-138.

3.

Administration of nitrite after chlorine gas exposure prevents lung injury: effect of administration modality.

Samal AA, Honavar J, Brandon A, Bradley KM, Doran S, Liu Y, Dunaway C, Steele C, Postlethwait EM, Squadrito GL, Fanucchi MV, Matalon S, Patel RP.

Free Radic Biol Med. 2012 Oct 1;53(7):1431-9. doi: 10.1016/j.freeradbiomed.2012.08.007. Epub 2012 Aug 11.

4.

Targeted aerosolized delivery of ascorbate in the lungs of chlorine-exposed rats.

Bracher A, Doran SF, Squadrito GL, Postlethwait EM, Bowen L, Matalon S.

J Aerosol Med Pulm Drug Deliv. 2012 Dec;25(6):333-41. doi: 10.1089/jamp.2011.0963. Epub 2012 Mar 6.

5.

Corticosteroid treatment inhibits airway hyperresponsiveness and lung injury in a murine model of chemical-induced airway inflammation.

Wigenstam E, Jonasson S, Koch B, Bucht A.

Toxicology. 2012 Nov 15;301(1-3):66-71. doi: 10.1016/j.tox.2012.06.020. Epub 2012 Jul 6.

PMID:
22776411
6.

Neutrophils mediate airway hyperresponsiveness after chlorine-induced airway injury in the mouse.

McGovern TK, Goldberger M, Allard B, Farahnak S, Hamamoto Y, O'Sullivan M, Hirota N, Martel G, Rousseau S, Martin JG.

Am J Respir Cell Mol Biol. 2015 Apr;52(4):513-22. doi: 10.1165/rcmb.2013-0430OC.

PMID:
25192041
7.

Temporal expression of hypoxia-regulated genes is associated with early changes in redox status in irradiated lung.

Jackson IL, Zhang X, Hadley C, Rabbani ZN, Zhang Y, Marks S, Vujaskovic Z.

Free Radic Biol Med. 2012 Jul 15;53(2):337-46. doi: 10.1016/j.freeradbiomed.2012.04.014. Epub 2012 Apr 25.

8.

Inhalation of chlorine causes long-standing lung inflammation and airway hyperresponsiveness in a murine model of chemical-induced lung injury.

Jonasson S, Koch B, Bucht A.

Toxicology. 2013 Jan 7;303:34-42. doi: 10.1016/j.tox.2012.10.022. Epub 2012 Nov 9.

PMID:
23146759
9.
10.

Mitigation of chlorine gas lung injury in rats by postexposure administration of sodium nitrite.

Yadav AK, Doran SF, Samal AA, Sharma R, Vedagiri K, Postlethwait EM, Squadrito GL, Fanucchi MV, Roberts LJ 2nd, Patel RP, Matalon S.

Am J Physiol Lung Cell Mol Physiol. 2011 Mar;300(3):L362-9. doi: 10.1152/ajplung.00278.2010. Epub 2010 Dec 10.

11.

Chlorine gas exposure increases susceptibility to invasive lung fungal infection.

Gessner MA, Doran SF, Yu Z, Dunaway CW, Matalon S, Steele C.

Am J Physiol Lung Cell Mol Physiol. 2013 Jun 1;304(11):L765-73. doi: 10.1152/ajplung.00030.2013. Epub 2013 Apr 5.

12.

Nitrite therapy improves survival postexposure to chlorine gas.

Honavar J, Doran S, Oh JY, Steele C, Matalon S, Patel RP.

Am J Physiol Lung Cell Mol Physiol. 2014 Dec 1;307(11):L888-94. doi: 10.1152/ajplung.00079.2014. Epub 2014 Oct 17.

13.

Endogenous osteopontin promotes ozone-induced neutrophil recruitment to the lungs and airway hyperresponsiveness to methacholine.

Barreno RX, Richards JB, Schneider DJ, Cromar KR, Nadas AJ, Hernandez CB, Hallberg LM, Price RE, Hashmi SS, Blackburn MR, Haque IU, Johnston RA.

Am J Physiol Lung Cell Mol Physiol. 2013 Jul 15;305(2):L118-29. doi: 10.1152/ajplung.00080.2013. Epub 2013 May 10.

14.

Acute lung injury induced by chlorine inhalation in C57BL/6 and FVB/N mice.

Tian X, Tao H, Brisolara J, Chen J, Rando RJ, Hoyle GW.

Inhal Toxicol. 2008 Jul;20(9):783-93. doi: 10.1080/08958370802007841 .

PMID:
18645717
15.

A metalloporphyrin superoxide dismutase mimetic protects against paraquat-induced lung injury in vivo.

Day BJ, Crapo JD.

Toxicol Appl Pharmacol. 1996 Sep;140(1):94-100.

PMID:
8806874
16.

Low molecular weight catalytic metalloporphyrin antioxidant AEOL 10150 protects lungs from fractionated radiation.

Rabbani ZN, Salahuddin FK, Yarmolenko P, Batinic-Haberle I, Thrasher BA, Gauter-Fleckenstein B, Dewhirst MW, Anscher MS, Vujaskovic Z.

Free Radic Res. 2007 Nov;41(11):1273-82.

PMID:
17957541
17.

Time course of airway remodelling after an acute chlorine gas exposure in mice.

Tuck SA, Ramos-Barbón D, Campbell H, McGovern T, Karmouty-Quintana H, Martin JG.

Respir Res. 2008 Aug 14;9:61. doi: 10.1186/1465-9921-9-61.

18.

Postexposure administration of a {beta}2-agonist decreases chlorine-induced airway hyperreactivity in mice.

Song W, Wei S, Liu G, Yu Z, Estell K, Yadav AK, Schwiebert LM, Matalon S.

Am J Respir Cell Mol Biol. 2011 Jul;45(1):88-94. doi: 10.1165/rcmb.2010-0226OC. Epub 2010 Sep 20.

19.

Abnormal epithelial structure and chronic lung inflammation after repair of chlorine-induced airway injury.

Mo Y, Chen J, Humphrey DM Jr, Fodah RA, Warawa JM, Hoyle GW.

Am J Physiol Lung Cell Mol Physiol. 2015 Jan 15;308(2):L168-78. doi: 10.1152/ajplung.00226.2014. Epub 2014 Nov 14.

20.

Ascorbate and deferoxamine administration after chlorine exposure decrease mortality and lung injury in mice.

Zarogiannis SG, Jurkuvenaite A, Fernandez S, Doran SF, Yadav AK, Squadrito GL, Postlethwait EM, Bowen L, Matalon S.

Am J Respir Cell Mol Biol. 2011 Aug;45(2):386-92. doi: 10.1165/rcmb.2010-0432OC. Epub 2010 Dec 3.

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