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Items: 1 to 20 of 97

1.

The reverse transcription inhibitor abacavir shows anticancer activity in prostate cancer cell lines.

Carlini F, Ridolfi B, Molinari A, Parisi C, Bozzuto G, Toccacieli L, Formisano G, De Orsi D, Paradisi S, Grober OM, Ravo M, Weisz A, Arcieri R, Vella S, Gaudi S.

PLoS One. 2010 Dec 3;5(12):e14221. doi: 10.1371/journal.pone.0014221.

2.

A tumor-promoting mechanism mediated by retrotransposon-encoded reverse transcriptase is active in human transformed cell lines.

Sciamanna I, Gualtieri A, Cossetti C, Osimo EF, Ferracin M, Macchia G, Aricò E, Prosseda G, Vitullo P, Misteli T, Spadafora C.

Oncotarget. 2013 Dec;4(12):2271-87.

3.
4.

Inhibition of LINE-1 retrotransposon-encoded reverse transcriptase modulates the expression of cell differentiation genes in breast cancer cells.

Patnala R, Lee SH, Dahlstrom JE, Ohms S, Chen L, Dheen ST, Rangasamy D.

Breast Cancer Res Treat. 2014 Jan;143(2):239-53. doi: 10.1007/s10549-013-2812-7. Epub 2013 Dec 12.

5.

Effectiveness of the histone deacetylase inhibitor (S)-2 against LNCaP and PC3 human prostate cancer cells.

Laurenzana A, Balliu M, Cellai C, Romanelli MN, Paoletti F.

PLoS One. 2013;8(3):e58267. doi: 10.1371/journal.pone.0058267. Epub 2013 Mar 4.

6.

The antiretroviral nucleoside analogue Abacavir reduces cell growth and promotes differentiation of human medulloblastoma cells.

Rossi A, Russo G, Puca A, La Montagna R, Caputo M, Mattioli E, Lopez M, Giordano A, Pentimalli F.

Int J Cancer. 2009 Jul 1;125(1):235-43. doi: 10.1002/ijc.24331.

7.

A LINE-1-encoded reverse transcriptase-dependent regulatory mechanism is active in embryogenesis and tumorigenesis.

Spadafora C.

Ann N Y Acad Sci. 2015 Apr;1341:164-71. doi: 10.1111/nyas.12637. Epub 2015 Jan 13.

PMID:
25586649
8.
9.

Resistance and cross-resistance to abacavir.

Moyle G.

HIV Med. 2001 Jul;2(3):154-62. Review.

11.

Anticancer efficacy of simvastatin on prostate cancer cells and tumor xenografts is associated with inhibition of Akt and reduced prostate-specific antigen expression.

Kochuparambil ST, Al-Husein B, Goc A, Soliman S, Somanath PR.

J Pharmacol Exp Ther. 2011 Feb;336(2):496-505. doi: 10.1124/jpet.110.174870. Epub 2010 Nov 8.

12.

Emodin inhibits the proliferation of PC3 prostate cancer cells in vitro via the Notch signaling pathway.

Deng G, Ju X, Meng Q, Yu ZJ, Ma LB.

Mol Med Rep. 2015 Sep;12(3):4427-33. doi: 10.3892/mmr.2015.3923. Epub 2015 Jun 12.

PMID:
26081222
13.

In vitro modulation of tumor progression-associated properties of hormone refractory prostate carcinoma cell lines by cytokines.

Sokoloff MH, Tso CL, Kaboo R, Taneja S, Pang S, deKernion JB, Belldegrun AS.

Cancer. 1996 May 1;77(9):1862-72.

14.

Elevated AKR1C3 expression promotes prostate cancer cell survival and prostate cell-mediated endothelial cell tube formation: implications for prostate cancer progression.

Dozmorov MG, Azzarello JT, Wren JD, Fung KM, Yang Q, Davis JS, Hurst RE, Culkin DJ, Penning TM, Lin HK.

BMC Cancer. 2010 Dec 6;10:672. doi: 10.1186/1471-2407-10-672.

15.

Anti-tumor activity of non-nucleosidic reverse transcriptase inhibitors.

Landriscina M, Spadafora C, Cignarelli M, Barone C.

Curr Pharm Des. 2007;13(7):737-47. Review.

PMID:
17346188
16.

A reverse transcriptase-dependent mechanism plays central roles in fundamental biological processes.

Spadafora C.

Syst Biol Reprod Med. 2008 Jan-Feb;54(1):11-21. doi: 10.1080/19396360701876815. Review.

PMID:
18543862
17.

Anti-tumoral effect of the non-nucleoside DNMT inhibitor RG108 in human prostate cancer cells.

Graça I, Sousa EJ, Baptista T, Almeida M, Ramalho-Carvalho J, Palmeira C, Henrique R, Jerónimo C.

Curr Pharm Des. 2014;20(11):1803-11.

PMID:
23888969
18.

Genistein induces cell growth inhibition in prostate cancer through the suppression of telomerase activity.

Ouchi H, Ishiguro H, Ikeda N, Hori M, Kubota Y, Uemura H.

Int J Urol. 2005 Jan;12(1):73-80.

19.
20.

Reverse transcriptase inhibitors down-regulate cell proliferation in vitro and in vivo and restore thyrotropin signaling and iodine uptake in human thyroid anaplastic carcinoma.

Landriscina M, Fabiano A, Altamura S, Bagalà C, Piscazzi A, Cassano A, Spadafora C, Giorgino F, Barone C, Cignarelli M.

J Clin Endocrinol Metab. 2005 Oct;90(10):5663-71. Epub 2005 Jul 19.

PMID:
16030158

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