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Items: 1 to 20 of 94

1.

Epigenetic alterations in liver of C57BL/6J mice after short-term inhalational exposure to 1,3-butadiene.

Koturbash I, Scherhag A, Sorrentino J, Sexton K, Bodnar W, Tryndyak V, Latendresse JR, Swenberg JA, Beland FA, Pogribny IP, Rusyn I.

Environ Health Perspect. 2011 May;119(5):635-40. doi: 10.1289/ehp.1002910. Epub 2010 Dec 13.

2.

Epigenetic events determine tissue-specific toxicity of inhalational exposure to the genotoxic chemical 1,3-butadiene in male C57BL/6J mice.

Chappell G, Kobets T, O'Brien B, Tretyakova N, Sangaraju D, Kosyk O, Sexton KG, Bodnar W, Pogribny IP, Rusyn I.

Toxicol Sci. 2014 Dec;142(2):375-84. doi: 10.1093/toxsci/kfu191. Epub 2014 Sep 18.

3.

Epigenetic mechanisms of mouse interstrain variability in genotoxicity of the environmental toxicant 1,3-butadiene.

Koturbash I, Scherhag A, Sorrentino J, Sexton K, Bodnar W, Swenberg JA, Beland FA, Pardo-Manuel Devillena F, Rusyn I, Pogribny IP.

Toxicol Sci. 2011 Aug;122(2):448-56. doi: 10.1093/toxsci/kfr133. Epub 2011 May 20.

4.

Genotoxicity of 1,3-butadiene and its epoxy intermediates.

Walker VE, Walker DM, Meng Q, McDonald JD, Scott BR, Seilkop SK, Claffey DJ, Upton PB, Powley MW, Swenberg JA, Henderson RF; Health Review Committee.

Res Rep Health Eff Inst. 2009 Aug;(144):3-79.

PMID:
20017413
5.

Molecular dosimetry of N-7 guanine adduct formation in mice and rats exposed to 1,3-butadiene.

Koc H, Tretyakova NY, Walker VE, Henderson RF, Swenberg JA.

Chem Res Toxicol. 1999 Jul;12(7):566-74.

PMID:
10409395
6.
7.

Dose- and time-dependent epigenetic changes in the livers of Fisher 344 rats exposed to furan.

Conti Ad, Kobets T, Escudero-Lourdes C, Montgomery B, Tryndyak V, Beland FA, Doerge DR, Pogribny IP.

Toxicol Sci. 2014 Jun;139(2):371-80. doi: 10.1093/toxsci/kfu044. Epub 2014 Mar 10.

9.

1,3-butadiene: cancer, mutations, and adducts. Part II: Roles of two metabolites of 1,3-butadiene in mediating its in vivo genotoxicity.

Recio L, Saranko CJ, Steen AM.

Res Rep Health Eff Inst. 2000 Mar;(92):49-87; discussion 141-9.

PMID:
10925839
10.

NanoHPLC-nanoESI(+)-MS/MS quantitation of bis-N7-guanine DNA-DNA cross-links in tissues of B6C3F1 mice exposed to subppm levels of 1,3-butadiene.

Sangaraju D, Goggin M, Walker V, Swenberg J, Tretyakova N.

Anal Chem. 2012 Feb 7;84(3):1732-9. doi: 10.1021/ac203079c. Epub 2012 Jan 26.

11.

1,3-butadiene: cancer, mutations, and adducts. Part IV: Molecular dosimetry of 1,3-butadiene.

Blair IA, Oe T, Kambouris S, Chaudhary AK.

Res Rep Health Eff Inst. 2000 Mar;(92):151-90; discussion 211-9.

PMID:
10925841
12.

Dose responses for DNA adduct formation in tissues of rats and mice exposed by inhalation to low concentrations of 1,3-[2,3-[(14)C]-butadiene.

Booth ED, Kilgour JD, Robinson SA, Watson WP.

Chem Biol Interact. 2004 Mar 15;147(2):195-211.

PMID:
15013821
13.

HPLC-ESI+-MS/MS analysis of N7-guanine-N7-guanine DNA cross-links in tissues of mice exposed to 1,3-butadiene.

Goggin M, Loeber R, Park S, Walker V, Wickliffe J, Tretyakova N.

Chem Res Toxicol. 2007 May;20(5):839-47. Epub 2007 Apr 25.

PMID:
17455958
14.

DNA adducts in rats and mice following exposure to [4-14C]-1,2-epoxy-3-butene and to [2,3-14C]-1,3-butadiene.

Boogaard PJ, de Kloe KP, Booth ED, Watson WP.

Chem Biol Interact. 2004 Jun 30;148(1-2):69-92.

PMID:
15223358
16.

Histone H3 lysine 9 and H4 lysine 20 trimethylation and the expression of Suv4-20h2 and Suv-39h1 histone methyltransferases in hepatocarcinogenesis induced by methyl deficiency in rats.

Pogribny IP, Ross SA, Tryndyak VP, Pogribna M, Poirier LA, Karpinets TV.

Carcinogenesis. 2006 Jun;27(6):1180-6. Epub 2006 Feb 23.

PMID:
16497704
18.

In vivo doses of butadiene epoxides as estimated from in vitro enzyme kinetics by using cob(I)alamin and measured hemoglobin adducts: an inter-species extrapolation approach.

Motwani HV, Törnqvist M.

Toxicol Appl Pharmacol. 2014 Dec 15;281(3):276-84. doi: 10.1016/j.taap.2014.10.011. Epub 2014 Nov 5.

PMID:
25448046
19.

Inhalation toxicology and carcinogenicity of 1,3-butadiene in B6C3F1 mice following 65 weeks of exposure.

Melnick RL, Huff JE, Roycroft JH, Chou BJ, Miller RA.

Environ Health Perspect. 1990 Jun;86:27-36.

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