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Items: 1 to 20 of 206

1.

Homozygous loss of ADAM3A revealed by genome-wide analysis of pediatric high-grade glioma and diffuse intrinsic pontine gliomas.

Barrow J, Adamowicz-Brice M, Cartmill M, MacArthur D, Lowe J, Robson K, Brundler MA, Walker DA, Coyle B, Grundy R.

Neuro Oncol. 2011 Feb;13(2):212-22. doi: 10.1093/neuonc/noq158. Epub 2010 Dec 7.

2.

Whole-genome profiling of pediatric diffuse intrinsic pontine gliomas highlights platelet-derived growth factor receptor alpha and poly (ADP-ribose) polymerase as potential therapeutic targets.

Zarghooni M, Bartels U, Lee E, Buczkowicz P, Morrison A, Huang A, Bouffet E, Hawkins C.

J Clin Oncol. 2010 Mar 10;28(8):1337-44. doi: 10.1200/JCO.2009.25.5463. Epub 2010 Feb 8.

PMID:
20142589
3.

High-resolution array copy number analyses for detection of deletion, gain, amplification and copy-neutral LOH in primary neuroblastoma tumors: four cases of homozygous deletions of the CDKN2A gene.

Carén H, Erichsen J, Olsson L, Enerbäck C, Sjöberg RM, Abrahamsson J, Kogner P, Martinsson T.

BMC Genomics. 2008 Jul 29;9:353. doi: 10.1186/1471-2164-9-353.

4.

Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease.

Paugh BS, Qu C, Jones C, Liu Z, Adamowicz-Brice M, Zhang J, Bax DA, Coyle B, Barrow J, Hargrave D, Lowe J, Gajjar A, Zhao W, Broniscer A, Ellison DW, Grundy RG, Baker SJ.

J Clin Oncol. 2010 Jun 20;28(18):3061-8. doi: 10.1200/JCO.2009.26.7252. Epub 2010 May 17.

5.

Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification.

Korshunov A, Remke M, Werft W, Benner A, Ryzhova M, Witt H, Sturm D, Wittmann A, Schöttler A, Felsberg J, Reifenberger G, Rutkowski S, Scheurlen W, Kulozik AE, von Deimling A, Lichter P, Pfister SM.

J Clin Oncol. 2010 Jun 20;28(18):3054-60. doi: 10.1200/JCO.2009.25.7121. Epub 2010 May 17.

PMID:
20479417
6.

Frequent deletion of CDKN2A and recurrent coamplification of KIT, PDGFRA, and KDR in fibrosarcoma of bone--an array comparative genomic hybridization study.

Niini T, López-Guerrero JA, Ninomiya S, Guled M, Hattinger CM, Michelacci F, Böhling T, Llombart-Bosch A, Picci P, Serra M, Knuutila S.

Genes Chromosomes Cancer. 2010 Feb;49(2):132-43. doi: 10.1002/gcc.20727.

PMID:
19862822
7.

MYCN amplification predicts poor outcome for patients with supratentorial primitive neuroectodermal tumors of the central nervous system .

Gessi M, von Bueren A, Treszl A, zur Mühlen A, Hartmann W, Warmuth-Metz M, Rutkowski S, Pietsch T.

Neuro Oncol. 2014 Jul;16(7):924-32.

8.

Genomic aberrations in pediatric diffuse intrinsic pontine gliomas.

Warren KE, Killian K, Suuriniemi M, Wang Y, Quezado M, Meltzer PS.

Neuro Oncol. 2012 Mar;14(3):326-32. doi: 10.1093/neuonc/nor190. Epub 2011 Nov 7.

9.

Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma.

Paugh BS, Broniscer A, Qu C, Miller CP, Zhang J, Tatevossian RG, Olson JM, Geyer JR, Chi SN, da Silva NS, Onar-Thomas A, Baker JN, Gajjar A, Ellison DW, Baker SJ.

J Clin Oncol. 2011 Oct 20;29(30):3999-4006. doi: 10.1200/JCO.2011.35.5677. Epub 2011 Sep 19.

10.

Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci.

Pfister S, Remke M, Benner A, Mendrzyk F, Toedt G, Felsberg J, Wittmann A, Devens F, Gerber NU, Joos S, Kulozik A, Reifenberger G, Rutkowski S, Wiestler OD, Radlwimmer B, Scheurlen W, Lichter P, Korshunov A.

J Clin Oncol. 2009 Apr 1;27(10):1627-36. doi: 10.1200/JCO.2008.17.9432. Epub 2009 Mar 2.

PMID:
19255330
11.

Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas.

Puget S, Philippe C, Bax DA, Job B, Varlet P, Junier MP, Andreiuolo F, Carvalho D, Reis R, Guerrini-Rousseau L, Roujeau T, Dessen P, Richon C, Lazar V, Le Teuff G, Sainte-Rose C, Geoerger B, Vassal G, Jones C, Grill J.

PLoS One. 2012;7(2):e30313. doi: 10.1371/journal.pone.0030313. Epub 2012 Feb 28.

12.

Comparative genomic and proteomic analysis of high grade glioma primary cultures and matched tumor in situ.

Howley R, Kinsella P, Buckley PG, Alcock L, Jansen M, Heffernan J, Stallings RL, Brett FM, Amberger-Murphy V, Farrell MA.

Exp Cell Res. 2012 Oct 15;318(17):2245-56. doi: 10.1016/j.yexcr.2012.06.007. Epub 2012 Jun 15.

PMID:
22705586
13.

Genetic risk variants in the CDKN2A/B, RTEL1 and EGFR genes are associated with somatic biomarkers in glioma.

Ghasimi S, Wibom C, Dahlin AM, Brännström T, Golovleva I, Andersson U, Melin B.

J Neurooncol. 2016 May;127(3):483-92. doi: 10.1007/s11060-016-2066-4. Epub 2016 Feb 2.

14.

Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas.

Paugh BS, Zhu X, Qu C, Endersby R, Diaz AK, Zhang J, Bax DA, Carvalho D, Reis RM, Onar-Thomas A, Broniscer A, Wetmore C, Zhang J, Jones C, Ellison DW, Baker SJ.

Cancer Res. 2013 Oct 15;73(20):6219-29. doi: 10.1158/0008-5472.CAN-13-1491. Epub 2013 Aug 22.

15.

Histopathological spectrum of paediatric diffuse intrinsic pontine glioma: diagnostic and therapeutic implications.

Buczkowicz P, Bartels U, Bouffet E, Becher O, Hawkins C.

Acta Neuropathol. 2014 Oct;128(4):573-81. doi: 10.1007/s00401-014-1319-6. Epub 2014 Jul 22.

16.

Comparative multidimensional molecular analyses of pediatric diffuse intrinsic pontine glioma reveals distinct molecular subtypes.

Saratsis AM, Kambhampati M, Snyder K, Yadavilli S, Devaney JM, Harmon B, Hall J, Raabe EH, An P, Weingart M, Rood BR, Magge SN, MacDonald TJ, Packer RJ, Nazarian J.

Acta Neuropathol. 2014;127(6):881-95. doi: 10.1007/s00401-013-1218-2. Epub 2013 Dec 3.

17.

Morphologic characteristics and immunohistochemical profile of diffuse intrinsic pontine gliomas.

Ballester LY, Wang Z, Shandilya S, Miettinen M, Burger PC, Eberhart CG, Rodriguez FJ, Raabe E, Nazarian J, Warren K, Quezado MM.

Am J Surg Pathol. 2013 Sep;37(9):1357-64. doi: 10.1097/PAS.0b013e318294e817.

18.

Genetic Analysis of Diffuse High-Grade Astrocytomas in Infancy Defines a Novel Molecular Entity.

Gielen GH, Gessi M, Buttarelli FR, Baldi C, Hammes J, zur Muehlen A, Doerner E, Denkhaus D, Warmuth-Metz M, Giangaspero F, Lauriola L, von Bueren AO, Kramm CM, Waha A, Pietsch T.

Brain Pathol. 2015 Jul;25(4):409-17. doi: 10.1111/bpa.12210. Epub 2014 Dec 19.

PMID:
25231549
19.

Fast detection of MYCN copy number alterations in brain neuronal tumors by real-time PCR.

Malakho SG, Korshunov A, Stroganova AM, Poltaraus AB.

J Clin Lab Anal. 2008;22(2):123-30. doi: 10.1002/jcla.20232.

PMID:
18348317
20.

Frequent loss of chromosome 9, homozygous CDKN2A/p14(ARF)/CDKN2B deletion and low TSC1 mRNA expression in pleomorphic xanthoastrocytomas.

Weber RG, Hoischen A, Ehrler M, Zipper P, Kaulich K, Blaschke B, Becker AJ, Weber-Mangal S, Jauch A, Radlwimmer B, Schramm J, Wiestler OD, Lichter P, Reifenberger G.

Oncogene. 2007 Feb 15;26(7):1088-97. Epub 2006 Aug 7.

PMID:
16909113

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