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Items: 1 to 20 of 42

1.

The antagonism between MCT-1 and p53 affects the tumorigenic outcomes.

Kasiappan R, Shih HJ, Wu MH, Choy C, Lin TD, Chen L, Hsu HL.

Mol Cancer. 2010 Dec 7;9:311. doi: 10.1186/1476-4598-9-311.

2.

Loss of p53 and MCT-1 overexpression synergistically promote chromosome instability and tumorigenicity.

Kasiappan R, Shih HJ, Chu KL, Chen WT, Liu HP, Huang SF, Choy CO, Shu CL, Din R, Chu JS, Hsu HL.

Mol Cancer Res. 2009 Apr;7(4):536-48. doi: 10.1158/1541-7786.MCR-08-0422.

3.

MCT-1 oncogene downregulates p53 and destabilizes genome structure in the response to DNA double-strand damage.

Hsu HL, Choy CO, Kasiappan R, Shih HJ, Sawyer JR, Shu CL, Chu KL, Chen YR, Hsu HF, Gartenhaus RB.

DNA Repair (Amst). 2007 Sep 1;6(9):1319-32. Epub 2007 Apr 6.

PMID:
17416211
4.

Targeting MCT-1 oncogene inhibits Shc pathway and xenograft tumorigenicity.

Shih HJ, Chen HH, Chen YA, Wu MH, Liou GG, Chang WW, Chen L, Wang LH, Hsu HL.

Oncotarget. 2012 Nov;3(11):1401-15.

5.

MCT-1 oncogene contributes to increased in vivo tumorigenicity of MCF7 cells by promotion of angiogenesis and inhibition of apoptosis.

Levenson AS, Thurn KE, Simons LA, Veliceasa D, Jarrett J, Osipo C, Jordan VC, Volpert OV, Satcher RL Jr, Gartenhaus RB.

Cancer Res. 2005 Dec 1;65(23):10651-6.

6.

Identification and characterization of a novel enhancer for the human MCT-1 oncogene promoter.

Shi B, Levenson V, Gartenhaus RB.

J Cell Biochem. 2003 Sep 1;90(1):68-79.

PMID:
12938157
7.

miR-605 joins p53 network to form a p53:miR-605:Mdm2 positive feedback loop in response to stress.

Xiao J, Lin H, Luo X, Luo X, Wang Z.

EMBO J. 2011 Feb 2;30(3):524-32. doi: 10.1038/emboj.2010.347. Epub 2011 Jan 7.

8.

Transcriptional repression of the anti-apoptotic survivin gene by wild type p53.

Hoffman WH, Biade S, Zilfou JT, Chen J, Murphy M.

J Biol Chem. 2002 Feb 1;277(5):3247-57. Epub 2001 Nov 19.

9.

p53-dependent down-regulation of telomerase is mediated by p21waf1.

Shats I, Milyavsky M, Tang X, Stambolsky P, Erez N, Brosh R, Kogan I, Braunstein I, Tzukerman M, Ginsberg D, Rotter V.

J Biol Chem. 2004 Dec 3;279(49):50976-85. Epub 2004 Sep 15.

10.

Reciprocal activation between PLK1 and Stat3 contributes to survival and proliferation of esophageal cancer cells.

Zhang Y, Du XL, Wang CJ, Lin DC, Ruan X, Feng YB, Huo YQ, Peng H, Cui JL, Zhang TT, Wang YQ, Zhang H, Zhan QM, Wang MR.

Gastroenterology. 2012 Mar;142(3):521-530.e3. doi: 10.1053/j.gastro.2011.11.023. Epub 2011 Nov 19.

PMID:
22108192
11.

HDAC2 overexpression confers oncogenic potential to human lung cancer cells by deregulating expression of apoptosis and cell cycle proteins.

Jung KH, Noh JH, Kim JK, Eun JW, Bae HJ, Xie HJ, Chang YG, Kim MG, Park H, Lee JY, Nam SW.

J Cell Biochem. 2012 Jun;113(6):2167-77. doi: 10.1002/jcb.24090.

PMID:
22492270
12.

A positive feedback mechanism in the transcriptional activation of Apaf-1 by p53 and the coactivator Zac-1.

Rozenfeld-Granot G, Krishnamurthy J, Kannan K, Toren A, Amariglio N, Givol D, Rechavi G.

Oncogene. 2002 Feb 28;21(10):1469-76.

13.

Rad is a p53 direct transcriptional target that inhibits cell migration and is frequently silenced in lung carcinoma cells.

Hsiao BY, Chen CC, Hsieh PC, Chang TK, Yeh YC, Wu YC, Hsu HS, Wang FF, Chou TY.

J Mol Med (Berl). 2011 May;89(5):481-92. doi: 10.1007/s00109-010-0717-z. Epub 2011 Jan 11.

PMID:
21221513
14.

The proapoptotic gene SIVA is a direct transcriptional target for the tumor suppressors p53 and E2F1.

Fortin A, MacLaurin JG, Arbour N, Cregan SP, Kushwaha N, Callaghan SM, Park DS, Albert PR, Slack RS.

J Biol Chem. 2004 Jul 2;279(27):28706-14. Epub 2004 Apr 22.

15.

The Meq oncoprotein of Marek's disease virus interacts with p53 and inhibits its transcriptional and apoptotic activities.

Deng X, Li X, Shen Y, Qiu Y, Shi Z, Shao D, Jin Y, Chen H, Ding C, Li L, Chen P, Ma Z.

Virol J. 2010 Nov 26;7:348. doi: 10.1186/1743-422X-7-348.

16.

Regulation of MCP-1 chemokine transcription by p53.

Hacke K, Rincon-Orozco B, Buchwalter G, Siehler SY, Wasylyk B, Wiesmüller L, Rösl F.

Mol Cancer. 2010 Apr 20;9:82. doi: 10.1186/1476-4598-9-82.

17.

The prognostic and therapeutic relevance of p27kip1 in Ewing's family tumors.

Matsunobu T, Tanaka K, Matsumoto Y, Nakatani F, Sakimura R, Hanada M, Li X, Oda Y, Naruse I, Hoshino H, Tsuneyoshi M, Miura H, Iwamoto Y.

Clin Cancer Res. 2004 Feb 1;10(3):1003-12.

18.

DNA damage signalling recruits RREB-1 to the p53 tumour suppressor promoter.

Liu H, Hew HC, Lu ZG, Yamaguchi T, Miki Y, Yoshida K.

Biochem J. 2009 Aug 27;422(3):543-51. doi: 10.1042/BJ20090342.

PMID:
19558368
19.

pRb, Myc and p53 are critically involved in SV40 large T antigen repression of PDGF beta-receptor transcription.

Uramoto H, Hackzell A, Wetterskog D, Ballági A, Izumi H, Funa K.

J Cell Sci. 2004 Aug 1;117(Pt 17):3855-65. Epub 2004 Jul 20.

20.

The involvement of MCT-1 oncoprotein in inducing mitotic catastrophe and nuclear abnormalities.

Shih HJ, Chu KL, Wu MH, Wu PH, Chang WW, Chu JS, Wang LH, Takeuchi H, Ouchi T, Hsu HL.

Cell Cycle. 2012 Mar 1;11(5):934-52. doi: 10.4161/cc.11.5.19452. Epub 2012 Mar 1.

PMID:
22336915

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