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Comparative proteomics and pulmonary toxicity of instilled single-walled carbon nanotubes, crocidolite asbestos, and ultrafine carbon black in mice.

Teeguarden JG, Webb-Robertson BJ, Waters KM, Murray AR, Kisin ER, Varnum SM, Jacobs JM, Pounds JG, Zanger RC, Shvedova AA.

Toxicol Sci. 2011 Mar;120(1):123-35. doi: 10.1093/toxsci/kfq363. Epub 2010 Dec 6.


Factoring-in agglomeration of carbon nanotubes and nanofibers for better prediction of their toxicity versus asbestos.

Murray AR, Kisin ER, Tkach AV, Yanamala N, Mercer R, Young SH, Fadeel B, Kagan VE, Shvedova AA.

Part Fibre Toxicol. 2012 Apr 10;9:10. doi: 10.1186/1743-8977-9-10.


Influence of acid functionalization on the cardiopulmonary toxicity of carbon nanotubes and carbon black particles in mice.

Tong H, McGee JK, Saxena RK, Kodavanti UP, Devlin RB, Gilmour MI.

Toxicol Appl Pharmacol. 2009 Sep 15;239(3):224-32. doi: 10.1016/j.taap.2009.05.019. Epub 2009 May 27.


Long-term effects of carbon containing engineered nanomaterials and asbestos in the lung: one year postexposure comparisons.

Shvedova AA, Yanamala N, Kisin ER, Tkach AV, Murray AR, Hubbs A, Chirila MM, Keohavong P, Sycheva LP, Kagan VE, Castranova V.

Am J Physiol Lung Cell Mol Physiol. 2014 Jan;306(2):L170-82. doi: 10.1152/ajplung.00167.2013. Epub 2013 Nov 8.


Multi-walled carbon nanotube instillation impairs pulmonary function in C57BL/6 mice.

Wang X, Katwa P, Podila R, Chen P, Ke PC, Rao AM, Walters DM, Wingard CJ, Brown JM.

Part Fibre Toxicol. 2011 Aug 18;8:24. doi: 10.1186/1743-8977-8-24.


Multiwalled carbon nanotube-induced pulmonary inflammatory and fibrotic responses and genomic changes following aspiration exposure in mice: A 1-year postexposure study.

Snyder-Talkington BN, Dong C, Porter DW, Ducatman B, Wolfarth MG, Andrew M, Battelli L, Raese R, Castranova V, Guo NL, Qian Y.

J Toxicol Environ Health A. 2016;79(8):352-66. doi: 10.1080/15287394.2016.1159635. Epub 2016 Apr 19.


MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs.

Poulsen SS, Saber AT, Williams A, Andersen O, Købler C, Atluri R, Pozzebon ME, Mucelli SP, Simion M, Rickerby D, Mortensen A, Jackson P, Kyjovska ZO, Mølhave K, Jacobsen NR, Jensen KA, Yauk CL, Wallin H, Halappanavar S, Vogel U.

Toxicol Appl Pharmacol. 2015 Apr 1;284(1):16-32. doi: 10.1016/j.taap.2014.12.011. Epub 2014 Dec 29.


A single intratracheal instillation of single-walled carbon nanotubes induced early lung fibrosis and subchronic tissue damage in mice.

Park EJ, Roh J, Kim SN, Kang MS, Han YA, Kim Y, Hong JT, Choi K.

Arch Toxicol. 2011 Sep;85(9):1121-31. doi: 10.1007/s00204-011-0655-8. Epub 2011 Apr 7.


Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice.

Shvedova AA, Kisin ER, Mercer R, Murray AR, Johnson VJ, Potapovich AI, Tyurina YY, Gorelik O, Arepalli S, Schwegler-Berry D, Hubbs AF, Antonini J, Evans DE, Ku BK, Ramsey D, Maynard A, Kagan VE, Castranova V, Baron P.

Am J Physiol Lung Cell Mol Physiol. 2005 Nov;289(5):L698-708. Epub 2005 Jun 10.


Pulmonary exposure to single-walled carbon nanotubes does not affect the early immune response against Toxoplasma gondii.

Swedin L, Arrighi R, Andersson-Willman B, Murray A, Chen Y, Karlsson MC, Georén SK, Tkach AV, Shvedova AA, Fadeel B, Barragan A, Scheynius A.

Part Fibre Toxicol. 2012 May 23;9:16. doi: 10.1186/1743-8977-9-16.


A review of carbon nanotube toxicity and assessment of potential occupational and environmental health risks.

Lam CW, James JT, McCluskey R, Arepalli S, Hunter RL.

Crit Rev Toxicol. 2006 Mar;36(3):189-217. Review.


Sequential exposure to carbon nanotubes and bacteria enhances pulmonary inflammation and infectivity.

Shvedova AA, Fabisiak JP, Kisin ER, Murray AR, Roberts JR, Tyurina YY, Antonini JM, Feng WH, Kommineni C, Reynolds J, Barchowsky A, Castranova V, Kagan VE.

Am J Respir Cell Mol Biol. 2008 May;38(5):579-90. Epub 2007 Dec 20.


Pulmonary and pleural inflammation after intratracheal instillation of short single-walled and multi-walled carbon nanotubes.

Fujita K, Fukuda M, Endoh S, Maru J, Kato H, Nakamura A, Shinohara N, Uchino K, Honda K.

Toxicol Lett. 2016 Aug 22;257:23-37. doi: 10.1016/j.toxlet.2016.05.025. Epub 2016 May 31.


Carbon Nanotube and Asbestos Exposures Induce Overlapping but Distinct Profiles of Lung Pathology in Non-Swiss Albino CF-1 Mice.

Frank EA, Carreira VS, Birch ME, Yadav JS.

Toxicol Pathol. 2016 Feb;44(2):211-25. doi: 10.1177/0192623315620587. Epub 2016 Feb 2.


Acute pulmonary effects of combined exposure to carbon nanotubes and ozone in mice.

Han SG, Andrews R, Gairola CG, Bhalla DK.

Inhal Toxicol. 2008 Feb;20(4):391-8. doi: 10.1080/08958370801904014 .


ESR evidence for in vivo formation of free radicals in tissue of mice exposed to single-walled carbon nanotubes.

Shvedova AA, Kisin ER, Murray AR, Mouithys-Mickalad A, Stadler K, Mason RP, Kadiiska M.

Free Radic Biol Med. 2014 Aug;73:154-65. doi: 10.1016/j.freeradbiomed.2014.05.010. Epub 2014 May 23.


Functionalized single-walled carbon nanotubes cause reversible acute lung injury and induce fibrosis in mice.

Zhang Y, Deng J, Zhang Y, Guo F, Li C, Zou Z, Xi W, Tang J, Sun Y, Yang P, Han Z, Li D, Jiang C.

J Mol Med (Berl). 2013 Jan;91(1):117-28. doi: 10.1007/s00109-012-0940-x. Epub 2012 Aug 10.


Dual acute proinflammatory and antifibrotic pulmonary effects of short palate, lung, and nasal epithelium clone-1 after exposure to carbon nanotubes.

Di YP, Tkach AV, Yanamala N, Stanley S, Gao S, Shurin MR, Kisin ER, Kagan VE, Shvedova A.

Am J Respir Cell Mol Biol. 2013 Nov;49(5):759-67. doi: 10.1165/rcmb.2012-0435OC.


A Single Aspiration of Rod-like Carbon Nanotubes Induces Asbestos-like Pulmonary Inflammation Mediated in Part by the IL-1 Receptor.

Rydman EM, Ilves M, Vanhala E, Vippola M, Lehto M, Kinaret PA, Pylkkänen L, Happo M, Hirvonen MR, Greco D, Savolainen K, Wolff H, Alenius H.

Toxicol Sci. 2015 Sep;147(1):140-55. doi: 10.1093/toxsci/kfv112. Epub 2015 Jun 5.


Investigation of the pulmonary bioactivity of double-walled carbon nanotubes.

Sager TM, Wolfarth MW, Battelli LA, Leonard SS, Andrew M, Steinbach T, Endo M, Tsuruoka S, Porter DW, Castranova V.

J Toxicol Environ Health A. 2013;76(15):922-36. doi: 10.1080/15287394.2013.825571.


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