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Does high weight loss in older adults with knee osteoarthritis affect bone-on-bone joint loads and muscle forces during walking?

Messier SP, Legault C, Loeser RF, Van Arsdale SJ, Davis C, Ettinger WH, DeVita P.

Osteoarthritis Cartilage. 2011 Mar;19(3):272-80. doi: 10.1016/j.joca.2010.11.010. Epub 2010 Dec 4.


Weight loss reduces knee-joint loads in overweight and obese older adults with knee osteoarthritis.

Messier SP, Gutekunst DJ, Davis C, DeVita P.

Arthritis Rheum. 2005 Jul;52(7):2026-32.


Do older adults with knee osteoarthritis place greater loads on the knee during gait? A preliminary study.

Messier SP, DeVita P, Cowan RE, Seay J, Young HC, Marsh AP.

Arch Phys Med Rehabil. 2005 Apr;86(4):703-9.


Effects of an intensive weight loss program on knee joint loading in obese adults with knee osteoarthritis.

Aaboe J, Bliddal H, Messier SP, Alkjær T, Henriksen M.

Osteoarthritis Cartilage. 2011 Jul;19(7):822-8. doi: 10.1016/j.joca.2011.03.006. Epub 2011 Apr 8.


Effects of intensive diet and exercise on knee joint loads, inflammation, and clinical outcomes among overweight and obese adults with knee osteoarthritis: the IDEA randomized clinical trial.

Messier SP, Mihalko SL, Legault C, Miller GD, Nicklas BJ, DeVita P, Beavers DP, Hunter DJ, Lyles MF, Eckstein F, Williamson JD, Carr JJ, Guermazi A, Loeser RF.

JAMA. 2013 Sep 25;310(12):1263-73. doi: 10.1001/jama.2013.277669.


Obesity is associated with higher absolute tibiofemoral contact and muscle forces during gait with and without knee osteoarthritis.

Harding GT, Dunbar MJ, Hubley-Kozey CL, Stanish WD, Astephen Wilson JL.

Clin Biomech (Bristol, Avon). 2016 Jan;31:79-86. doi: 10.1016/j.clinbiomech.2015.09.017. Epub 2015 Sep 30.


Knee joint loading in knee osteoarthritis: influence of abdominal and thigh fat.

Messier SP, Beavers DP, Loeser RF, Carr JJ, Khajanchi S, Legault C, Nicklas BJ, Hunter DJ, Devita P.

Med Sci Sports Exerc. 2014 Sep;46(9):1677-83. doi: 10.1249/MSS.0000000000000293.


Is increased joint loading detrimental to obese patients with knee osteoarthritis? A secondary data analysis from a randomized trial.

Henriksen M, Hunter DJ, Dam EB, Messier SP, Andriacchi TP, Lohmander LS, Aaboe J, Boesen M, Gudbergsen H, Bliddal H, Christensen R.

Osteoarthritis Cartilage. 2013 Dec;21(12):1865-75. doi: 10.1016/j.joca.2013.10.003. Epub 2013 Oct 14.


The relationship between ankle plantar flexor muscle moments and knee compressive forces in subjects with and without pain.

Robon MJ, Perell KL, Fang M, Guererro E.

Clin Biomech (Bristol, Avon). 2000 Aug;15(7):522-7.


Are There Sex Differences in Knee Cartilage Composition and Walking Mechanics in Healthy and Osteoarthritis Populations?

Kumar D, Souza RB, Subburaj K, MacLeod TD, Singh J, Calixto NE, Nardo L, Link TM, Li X, Lane NE, Majumdar S.

Clin Orthop Relat Res. 2015 Aug;473(8):2548-58. doi: 10.1007/s11999-015-4212-2.


Influences of alignment and obesity on knee joint loading in osteoarthritic gait.

Messier SP, Pater M, Beavers DP, Legault C, Loeser RF, Hunter DJ, DeVita P.

Osteoarthritis Cartilage. 2014 Jul;22(7):912-7. doi: 10.1016/j.joca.2014.05.013. Epub 2014 May 21.


Reductions in knee joint forces with weight loss are attenuated by gait adaptations in class III obesity.

DeVita P, Rider P, Hortobágyi T.

Gait Posture. 2016 Mar;45:25-30. doi: 10.1016/j.gaitpost.2015.12.040. Epub 2016 Jan 6.


Exercise and weight loss in obese older adults with knee osteoarthritis: a preliminary study.

Messier SP, Loeser RF, Mitchell MN, Valle G, Morgan TP, Rejeski WJ, Ettinger WH.

J Am Geriatr Soc. 2000 Sep;48(9):1062-72.


Managing Knee Osteoarthritis: The Effects of Body Weight Supported Physical Activity on Joint Pain, Function, and Thigh Muscle Strength.

Peeler J, Christian M, Cooper J, Leiter J, MacDonald P.

Clin J Sport Med. 2015 Nov;25(6):518-23. doi: 10.1097/JSM.0000000000000173.


Train High Eat Low for Osteoarthritis study (THE LO study): protocol for a randomized controlled trial.

Guerrero Y, Soomro N, Wilson G, Dam Y, Meiklejohn J, Simpson K, Smith R, Brand-Miller J, Simic M, O'Connor H, Mavros Y, Foroughi N, Poon T, Bradshaw K, March L, Vanwanseele B, Eckstein F, Fransen M, Bergamasco J, Anandacoomarasamy A, Singh MF.

J Physiother. 2015 Oct;61(4):217. doi: 10.1016/j.jphys.2015.05.020. Epub 2015 Aug 29.


The Intensive Diet and Exercise for Arthritis (IDEA) trial: design and rationale.

Messier SP, Legault C, Mihalko S, Miller GD, Loeser RF, DeVita P, Lyles M, Eckstein F, Hunter DJ, Williamson JD, Nicklas BJ.

BMC Musculoskelet Disord. 2009 Jul 28;10:93. doi: 10.1186/1471-2474-10-93.


The independent and combined effects of intensive weight loss and exercise training on bone mineral density in overweight and obese older adults with osteoarthritis.

Beavers DP, Beavers KM, Loeser RF, Walton NR, Lyles MF, Nicklas BJ, Shapses SA, Newman JJ, Messier SP.

Osteoarthritis Cartilage. 2014 Jun;22(6):726-33. doi: 10.1016/j.joca.2014.04.002. Epub 2014 Apr 15.


Increased joint loads during walking--a consequence of pain relief in knee osteoarthritis.

Henriksen M, Simonsen EB, Alkjaer T, Lund H, Graven-Nielsen T, Danneskiold-Samsøe B, Bliddal H.

Knee. 2006 Dec;13(6):445-50. Epub 2006 Sep 29.


Effects of a modified shoe on knee load in people with and those without knee osteoarthritis.

Bennell KL, Kean CO, Wrigley TV, Hinman RS.

Arthritis Rheum. 2013 Mar;65(3):701-9. doi: 10.1002/art.37788.


Exercise and dietary weight loss in overweight and obese older adults with knee osteoarthritis: the Arthritis, Diet, and Activity Promotion Trial.

Messier SP, Loeser RF, Miller GD, Morgan TM, Rejeski WJ, Sevick MA, Ettinger WH Jr, Pahor M, Williamson JD.

Arthritis Rheum. 2004 May;50(5):1501-10.

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