Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 106

1.

Genome-wide association scan allowing for epistasis in type 2 diabetes.

Bell JT, Timpson NJ, Rayner NW, Zeggini E, Frayling TM, Hattersley AT, Morris AP, McCarthy MI.

Ann Hum Genet. 2011 Jan;75(1):10-9. doi: 10.1111/j.1469-1809.2010.00629.x. Epub 2010 Dec 6.

2.

Detecting purely epistatic multi-locus interactions by an omnibus permutation test on ensembles of two-locus analyses.

Wongseree W, Assawamakin A, Piroonratana T, Sinsomros S, Limwongse C, Chaiyaratana N.

BMC Bioinformatics. 2009 Sep 17;10:294. doi: 10.1186/1471-2105-10-294.

3.

Development of GMDR-GPU for gene-gene interaction analysis and its application to WTCCC GWAS data for type 2 diabetes.

Zhu Z, Tong X, Zhu Z, Liang M, Cui W, Su K, Li MD, Zhu J.

PLoS One. 2013 Apr 23;8(4):e61943. doi: 10.1371/journal.pone.0061943. Print 2013.

4.

Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data.

Timpson NJ, Lindgren CM, Weedon MN, Randall J, Ouwehand WH, Strachan DP, Rayner NW, Walker M, Hitman GA, Doney AS, Palmer CN, Morris AD, Hattersley AT, Zeggini E, Frayling TM, McCarthy MI.

Diabetes. 2009 Feb;58(2):505-10. doi: 10.2337/db08-0906. Epub 2008 Dec 3.

5.

Replication and Relevance of Multiple Susceptibility Loci Discovered from Genome Wide Association Studies for Type 2 Diabetes in an Indian Population.

Phani NM, Adhikari P, Nagri SK, D'Souza SC, Satyamoorthy K, Rai PS.

PLoS One. 2016 Jun 16;11(6):e0157364. doi: 10.1371/journal.pone.0157364. eCollection 2016.

6.

Validation of type 2 diabetes risk variants identified by genome-wide association studies in Han Chinese population: a replication study and meta-analysis.

Chang YC, Liu PH, Yu YH, Kuo SS, Chang TJ, Jiang YD, Nong JY, Hwang JJ, Chuang LM.

PLoS One. 2014 Apr 15;9(4):e95045. doi: 10.1371/journal.pone.0095045. eCollection 2014.

7.

Association of the type 2 diabetes mellitus susceptibility gene, TCF7L2, with schizophrenia in an Arab-Israeli family sample.

Alkelai A, Greenbaum L, Lupoli S, Kohn Y, Sarner-Kanyas K, Ben-Asher E, Lancet D, Macciardi F, Lerer B.

PLoS One. 2012;7(1):e29228. doi: 10.1371/journal.pone.0029228. Epub 2012 Jan 11.

8.

In vitro scan for enhancers at the TCF7L2 locus.

Savic D, Park SY, Bailey KA, Bell GI, Nobrega MA.

Diabetologia. 2013 Jan;56(1):121-5. doi: 10.1007/s00125-012-2730-y. Epub 2012 Sep 26.

9.

Variants of the PPARG, IGF2BP2, CDKAL1, HHEX, and TCF7L2 genes confer risk of type 2 diabetes independently of BMI in the German KORA studies.

Herder C, Rathmann W, Strassburger K, Finner H, Grallert H, Huth C, Meisinger C, Gieger C, Martin S, Giani G, Scherbaum WA, Wichmann HE, Illig T.

Horm Metab Res. 2008 Oct;40(10):722-6. doi: 10.1055/s-2008-1078730. Epub 2008 Jul 2.

PMID:
18597214
10.

Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis.

Uimari O, Rahmioglu N, Nyholt DR, Vincent K, Missmer SA, Becker C, Morris AP, Montgomery GW, Zondervan KT.

Hum Reprod. 2017 Apr 1;32(4):780-793. doi: 10.1093/humrep/dex024.

11.

[Correlation between TCF7L2 gene polymorphism and genetic susceptibility in women with gestational diabetes mellitus].

Shi X, Cai Q, Zou M, Shen Y.

Zhonghua Fu Chan Ke Za Zhi. 2014 Aug;49(8):588-93. Chinese.

PMID:
25354859
12.

Transferability and fine mapping of type 2 diabetes loci in African Americans: the Candidate Gene Association Resource Plus Study.

Ng MC, Saxena R, Li J, Palmer ND, Dimitrov L, Xu J, Rasmussen-Torvik LJ, Zmuda JM, Siscovick DS, Patel SR, Crook ED, Sims M, Chen YD, Bertoni AG, Li M, Grant SF, Dupuis J, Meigs JB, Psaty BM, Pankow JS, Langefeld CD, Freedman BI, Rotter JI, Wilson JG, Bowden DW.

Diabetes. 2013 Mar;62(3):965-76. doi: 10.2337/db12-0266. Epub 2012 Nov 27.

13.

European genetic variants associated with type 2 diabetes in North African Arabs.

Cauchi S, Ezzidi I, El Achhab Y, Mtiraoui N, Chaieb L, Salah D, Nejjari C, Labrune Y, Yengo L, Beury D, Vaxillaire M, Mahjoub T, Chikri M, Froguel P.

Diabetes Metab. 2012 Oct;38(4):316-23. doi: 10.1016/j.diabet.2012.02.003. Epub 2012 Mar 29.

PMID:
22463974
14.

Contribution of common genetic variation to the risk of type 2 diabetes in the Mexican Mestizo population.

Gamboa-Meléndez MA, Huerta-Chagoya A, Moreno-Macías H, Vázquez-Cárdenas P, Ordóñez-Sánchez ML, Rodríguez-Guillén R, Riba L, Rodríguez-Torres M, Guerra-García MT, Guillén-Pineda LE, Choudhry S, Del Bosque-Plata L, Canizales-Quinteros S, Pérez-Ortiz G, Escobedo-Aguirre F, Parra A, Lerman-Garber I, Aguilar-Salinas CA, Tusié-Luna MT.

Diabetes. 2012 Dec;61(12):3314-21. doi: 10.2337/db11-0550. Epub 2012 Aug 24.

15.

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.

Saxena R, Elbers CC, Guo Y, Peter I, Gaunt TR, Mega JL, Lanktree MB, Tare A, Castillo BA, Li YR, Johnson T, Bruinenberg M, Gilbert-Diamond D, Rajagopalan R, Voight BF, Balasubramanyam A, Barnard J, Bauer F, Baumert J, Bhangale T, Böhm BO, Braund PS, Burton PR, Chandrupatla HR, Clarke R, Cooper-DeHoff RM, Crook ED, Davey-Smith G, Day IN, de Boer A, de Groot MC, Drenos F, Ferguson J, Fox CS, Furlong CE, Gibson Q, Gieger C, Gilhuijs-Pederson LA, Glessner JT, Goel A, Gong Y, Grant SF, Grobbee DE, Hastie C, Humphries SE, Kim CE, Kivimaki M, Kleber M, Meisinger C, Kumari M, Langaee TY, Lawlor DA, Li M, Lobmeyer MT, Maitland-van der Zee AH, Meijs MF, Molony CM, Morrow DA, Murugesan G, Musani SK, Nelson CP, Newhouse SJ, O'Connell JR, Padmanabhan S, Palmen J, Patel SR, Pepine CJ, Pettinger M, Price TS, Rafelt S, Ranchalis J, Rasheed A, Rosenthal E, Ruczinski I, Shah S, Shen H, Silbernagel G, Smith EN, Spijkerman AW, Stanton A, Steffes MW, Thorand B, Trip M, van der Harst P, van der A DL, van Iperen EP, van Setten J, van Vliet-Ostaptchouk JV, Verweij N, Wolffenbuttel BH, Young T, Zafarmand MH, Zmuda JM; Look AHEAD Research Group; DIAGRAM consortium, Boehnke M, Altshuler D, McCarthy M, Kao WH, Pankow JS, Cappola TP, Sever P, Poulter N, Caulfield M, Dominiczak A, Shields DC, Bhatt DL, Zhang L, Curtis SP, Danesh J, Casas JP, van der Schouw YT, Onland-Moret NC, Doevendans PA, Dorn GW 2nd, Farrall M, FitzGerald GA, Hamsten A, Hegele R, Hingorani AD, Hofker MH, Huggins GS, Illig T, Jarvik GP, Johnson JA, Klungel OH, Knowler WC, Koenig W, März W, Meigs JB, Melander O, Munroe PB, Mitchell BD, Bielinski SJ, Rader DJ, Reilly MP, Rich SS, Rotter JI, Saleheen D, Samani NJ, Schadt EE, Shuldiner AR, Silverstein R, Kottke-Marchant K, Talmud PJ, Watkins H, Asselbergs FW, de Bakker PI, McCaffery J, Wijmenga C, Sabatine MS, Wilson JG, Reiner A, Bowden DW, Hakonarson H, Siscovick DS, Keating BJ.

Am J Hum Genet. 2012 Mar 9;90(3):410-25. doi: 10.1016/j.ajhg.2011.12.022. Epub 2012 Feb 9. Erratum in: Am J Hum Genet. 2012 Apr 6;90(4):753. Sever, Peter [added]; Poulter, Neil [added] Bhatt, Deepak [corrected to Bhatt, Deepak L]; Asselbergs, Folkert [corrected to Asselbergs, Folkert W].

16.

Investigation of type 2 diabetes risk alleles support CDKN2A/B, CDKAL1, and TCF7L2 as susceptibility genes in a Han Chinese cohort.

Wen J, Rönn T, Olsson A, Yang Z, Lu B, Du Y, Groop L, Ling C, Hu R.

PLoS One. 2010 Feb 10;5(2):e9153. doi: 10.1371/journal.pone.0009153.

17.

Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk.

Sanghera DK, Ortega L, Han S, Singh J, Ralhan SK, Wander GS, Mehra NK, Mulvihill JJ, Ferrell RE, Nath SK, Kamboh MI.

BMC Med Genet. 2008 Jul 3;9:59. doi: 10.1186/1471-2350-9-59.

18.

Transcription factor-7-like 2 gene variants are strongly associated with type 2 diabetes in Lebanese subjects.

Nemr R, Turki A, Echtay A, Al-Zaben GS, Daher HS, Irani-Hakime NA, Keleshian SH, Almawi WY.

Diabetes Res Clin Pract. 2012 Dec;98(3):e23-7. doi: 10.1016/j.diabres.2012.09.044. Epub 2012 Oct 27.

PMID:
23107111
19.

Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively.

Wood AR, Tyrrell J, Beaumont R, Jones SE, Tuke MA, Ruth KS; GIANT consortium, Yaghootkar H, Freathy RM, Murray A, Frayling TM, Weedon MN.

Diabetologia. 2016 Jun;59(6):1214-21. doi: 10.1007/s00125-016-3908-5. Epub 2016 Mar 10.

20.

High-throughput analysis of epistasis in genome-wide association studies with BiForce.

Gyenesei A, Moody J, Semple CA, Haley CS, Wei WH.

Bioinformatics. 2012 Aug 1;28(15):1957-64. doi: 10.1093/bioinformatics/bts304. Epub 2012 May 21. Erratum in: Bioinformatics. 2013 Oct 15;29(20):2667-8.

Supplemental Content

Support Center