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Reprogramming of human primary somatic cells by OCT4 and chemical compounds.

Zhu S, Li W, Zhou H, Wei W, Ambasudhan R, Lin T, Kim J, Zhang K, Ding S.

Cell Stem Cell. 2010 Dec 3;7(6):651-5. doi: 10.1016/j.stem.2010.11.015. No abstract available.


Sphere formation permits Oct4 reprogramming of ciliary body epithelial cells into induced pluripotent stem cells.

Ni A, Wu MJ, Chavala SH.

Stem Cells Dev. 2014 Dec 15;23(24):3065-71. doi: 10.1089/scd.2014.0064.


The nuclear receptor Nr5a2 can replace Oct4 in the reprogramming of murine somatic cells to pluripotent cells.

Heng JC, Feng B, Han J, Jiang J, Kraus P, Ng JH, Orlov YL, Huss M, Yang L, Lufkin T, Lim B, Ng HH.

Cell Stem Cell. 2010 Feb 5;6(2):167-74. doi: 10.1016/j.stem.2009.12.009. Epub 2010 Jan 21.


Nuclear reprogramming with a non-integrating human RNA virus.

Driscoll CB, Tonne JM, El Khatib M, Cattaneo R, Ikeda Y, Devaux P.

Stem Cell Res Ther. 2015 Mar 26;6:48. doi: 10.1186/s13287-015-0035-z.


Sox transcription factors require selective interactions with Oct4 and specific transactivation functions to mediate reprogramming.

Aksoy I, Jauch R, Eras V, Chng WB, Chen J, Divakar U, Ng CK, Kolatkar PR, Stanton LW.

Stem Cells. 2013 Dec;31(12):2632-46. doi: 10.1002/stem.1522.


Reprogramming of somatic cells after fusion with induced pluripotent stem cells and nuclear transfer embryonic stem cells.

Sumer H, Jones KL, Liu J, Heffernan C, Tat PA, Upton KR, Verma PJ.

Stem Cells Dev. 2010 Feb;19(2):239-46. doi: 10.1089/scd.2009.0142.


Two-step generation of induced pluripotent stem cells from mouse fibroblasts using Id3 and Oct4.

Moon JH, Heo JS, Kwon S, Kim J, Hwang J, Kang PJ, Kim A, Kim HO, Whang KY, Yoon BS, You S.

J Mol Cell Biol. 2012 Feb;4(1):59-62. doi: 10.1093/jmcb/mjr038. Epub 2011 Nov 30. No abstract available.


Non-genetic direct reprogramming and biomimetic platforms in a preliminary study for adipose-derived stem cells into corneal endothelia-like cells.

Dai Y, Guo Y, Wang C, Liu Q, Yang Y, Li S, Guo X, Lian R, Yu R, Liu H, Chen J.

PLoS One. 2014 Oct 15;9(10):e109856. doi: 10.1371/journal.pone.0109856. eCollection 2014.


Increase developmental plasticity of human keratinocytes with gene suppression.

Li SC, Jin Y, Loudon WG, Song Y, Ma Z, Weiner LP, Zhong JF.

Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12793-8. doi: 10.1073/pnas.1100509108. Epub 2011 Jul 18.


Reprogramming factor stoichiometry influences the epigenetic state and biological properties of induced pluripotent stem cells.

Carey BW, Markoulaki S, Hanna JH, Faddah DA, Buganim Y, Kim J, Ganz K, Steine EJ, Cassady JP, Creyghton MP, Welstead GG, Gao Q, Jaenisch R.

Cell Stem Cell. 2011 Dec 2;9(6):588-98. doi: 10.1016/j.stem.2011.11.003.


Generation of induced pluripotent stem cells from human renal proximal tubular cells with only two transcription factors, OCT4 and SOX2.

Montserrat N, Ramírez-Bajo MJ, Xia Y, Sancho-Martinez I, Moya-Rull D, Miquel-Serra L, Yang S, Nivet E, Cortina C, González F, Izpisua Belmonte JC, Campistol JM.

J Biol Chem. 2012 Jul 13;287(29):24131-8. doi: 10.1074/jbc.M112.350413. Epub 2012 May 21.


Efficient induction of pluripotent stem cells from granulosa cells by Oct4 and Sox2.

Mao J, Zhang Q, Ye X, Liu K, Liu L.

Stem Cells Dev. 2014 Apr 1;23(7):779-89. doi: 10.1089/scd.2013.0325. Epub 2013 Nov 12.


Reptin regulates pluripotency of embryonic stem cells and somatic cell reprogramming through Oct4-dependent mechanism.

Do EK, Cheon HC, Jang IH, Choi EJ, Heo SC, Kang KT, Bae KH, Cho YS, Seo JK, Yoon JH, Lee TG, Kim JH.

Stem Cells. 2014 Dec;32(12):3126-36. doi: 10.1002/stem.1827.


Human fibroblast reprogramming to pluripotent stem cells regulated by the miR19a/b-PTEN axis.

He X, Cao Y, Wang L, Han Y, Zhong X, Zhou G, Cai Y, Zhang H, Gao P.

PLoS One. 2014 Apr 16;9(4):e95213. doi: 10.1371/journal.pone.0095213. eCollection 2014.


Fine-tuning of iPSC derivation by an inducible reprogramming system at the protein level.

Sui D, Sun Z, Xu C, Wu Y, Capecchi MR, Wu S, Li N.

Stem Cell Reports. 2014 May 8;2(5):721-33. doi: 10.1016/j.stemcr.2014.03.013. eCollection 2014 May 6.


And then there were none: no need for pluripotency factors to induce reprogramming.

Chou BK, Cheng L.

Cell Stem Cell. 2013 Sep 5;13(3):261-2. doi: 10.1016/j.stem.2013.08.004.


Chemically induced pluripotent stem cells (CiPSCs): a transgene-free approach.

Masuda S, Wu J, Hishida T, Pandian GN, Sugiyama H, Izpisua Belmonte JC.

J Mol Cell Biol. 2013 Oct;5(5):354-5. doi: 10.1093/jmcb/mjt034. Epub 2013 Sep 6.


Activation of AMP-activated protein kinase (AMPK) provides a metabolic barrier to reprogramming somatic cells into stem cells.

Vazquez-Martin A, Vellon L, Quirós PM, Cufí S, Ruiz de Galarreta E, Oliveras-Ferraros C, Martin AG, Martin-Castillo B, López-Otín C, Menendez JA.

Cell Cycle. 2012 Mar 1;11(5):974-89. doi: 10.4161/cc.11.5.19450. Epub 2012 Mar 1.


Inhibition of transforming growth factor β (TGF-β) signaling can substitute for Oct4 protein in reprogramming and maintain pluripotency.

Tan F, Qian C, Tang K, Abd-Allah SM, Jing N.

J Biol Chem. 2015 Feb 13;290(7):4500-11. doi: 10.1074/jbc.M114.609016. Epub 2014 Dec 29.


Conversion of partially reprogrammed cells to fully pluripotent stem cells is associated with further activation of stem cell maintenance- and gamete generation-related genes.

Kim JS, Choi HW, Choi S, Seo HG, Moon SH, Chung HM, Do JT.

Stem Cells Dev. 2014 Nov 1;23(21):2637-48. doi: 10.1089/scd.2014.0020. Epub 2014 Aug 20.

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