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Items: 1 to 20 of 100

1.

A major role for Bim in regulatory T cell homeostasis.

Chougnet CA, Tripathi P, Lages CS, Raynor J, Sholl A, Fink P, Plas DR, Hildeman DA.

J Immunol. 2011 Jan 1;186(1):156-63. doi: 10.4049/jimmunol.1001505. Epub 2010 Nov 22.

2.

Preferential control of induced regulatory T cell homeostasis via a Bim/Bcl-2 axis.

Wang X, Szymczak-Workman AL, Gravano DM, Workman CJ, Green DR, Vignali DA.

Cell Death Dis. 2012 Feb 9;3:e270. doi: 10.1038/cddis.2012.9.

3.

Bim/Bcl-2 balance is critical for maintaining naive and memory T cell homeostasis.

Wojciechowski S, Tripathi P, Bourdeau T, Acero L, Grimes HL, Katz JD, Finkelman FD, Hildeman DA.

J Exp Med. 2007 Jul 9;204(7):1665-75. Epub 2007 Jun 25.

4.

Bim-mediated apoptosis is not necessary for thymic negative selection to ubiquitous self-antigens.

Hu Q, Sader A, Parkman JC, Baldwin TA.

J Immunol. 2009 Dec 15;183(12):7761-7. doi: 10.4049/jimmunol.0902181. Epub .

5.

Cutting edge: mechanisms of IL-2-dependent maintenance of functional regulatory T cells.

Barron L, Dooms H, Hoyer KK, Kuswanto W, Hofmann J, O'Gorman WE, Abbas AK.

J Immunol. 2010 Dec 1;185(11):6426-30. doi: 10.4049/jimmunol.0903940. Epub 2010 Oct 29.

6.

Bim and Bcl-2 mutually affect the expression of the other in T cells.

Jorgensen TN, McKee A, Wang M, Kushnir E, White J, Refaeli Y, Kappler JW, Marrack P.

J Immunol. 2007 Sep 15;179(6):3417-24.

7.

Bim mediates apoptosis of CD127(lo) effector T cells and limits T cell memory.

Wojciechowski S, Jordan MB, Zhu Y, White J, Zajac AJ, Hildeman DA.

Eur J Immunol. 2006 Jul;36(7):1694-706.

8.

IL-6 and ICOS Antagonize Bim and Promote Regulatory T Cell Accrual with Age.

Raynor J, Karns R, Almanan M, Li KP, Divanovic S, Chougnet CA, Hildeman DA.

J Immunol. 2015 Aug 1;195(3):944-52. doi: 10.4049/jimmunol.1500443. Epub 2015 Jun 24.

9.

Conditional ablation of MHC-II suggests an indirect role for MHC-II in regulatory CD4 T cell maintenance.

Shimoda M, Mmanywa F, Joshi SK, Li T, Miyake K, Pihkala J, Abbas JA, Koni PA.

J Immunol. 2006 Jun 1;176(11):6503-11.

10.

The class III kinase Vps34 promotes T lymphocyte survival through regulating IL-7Rα surface expression.

McLeod IX, Zhou X, Li QJ, Wang F, He YW.

J Immunol. 2011 Nov 15;187(10):5051-61. doi: 10.4049/jimmunol.1100710. Epub 2011 Oct 21.

11.

The proapoptotic Bcl-2 family member Bim plays a central role during the development of virus-induced hepatitis.

Lauer C, Brunner T, Corazza N.

J Immunol. 2012 Jan 15;188(2):916-22. doi: 10.4049/jimmunol.1101864. Epub 2011 Dec 7.

12.

CD2-mediated regulation of peripheral CD4(+)  CD25(+) regulatory T-cell apoptosis accompanied by down-regulation of Bim.

Kashiwakura Y, Sakurai D, Kanno Y, Hashiguchi M, Kobayashi A, Kurosu A, Tokudome S, Kobata T, Kojima H.

Immunology. 2013 May;139(1):48-60. doi: 10.1111/imm.12054.

13.

Bim regulates BCR-induced entry of B cells into the cell cycle.

Craxton A, Draves KE, Clark EA.

Eur J Immunol. 2007 Oct;37(10):2715-22.

14.

Defective cell death signalling along the Bcl-2 regulated apoptosis pathway compromises Treg cell development and limits their functionality in mice.

Tischner D, Gaggl I, Peschel I, Kaufmann M, Tuzlak S, Drach M, Thuille N, Villunger A, Jan Wiegers G.

J Autoimmun. 2012 Feb;38(1):59-69. doi: 10.1016/j.jaut.2011.12.008. Epub 2012 Jan 17.

15.

Cutting edge: regulatory T cells do not mediate suppression via programmed cell death pathways.

Szymczak-Workman AL, Delgoffe GM, Green DR, Vignali DA.

J Immunol. 2011 Nov 1;187(9):4416-20. doi: 10.4049/jimmunol.1100548. Epub 2011 Sep 26.

16.

Transforming growth factor-beta signaling curbs thymic negative selection promoting regulatory T cell development.

Ouyang W, Beckett O, Ma Q, Li MO.

Immunity. 2010 May 28;32(5):642-53. doi: 10.1016/j.immuni.2010.04.012. Epub 2010 May 13.

17.

Distinguishing the proapoptotic and antiresorptive functions of risedronate in murine osteoclasts: role of the Akt pathway and the ERK/Bim axis.

Matsumoto T, Nagase Y, Iwasawa M, Yasui T, Masuda H, Kadono Y, Nakamura K, Tanaka S.

Arthritis Rheum. 2011 Dec;63(12):3908-17. doi: 10.1002/art.30646.

18.

Individual and overlapping roles of BH3-only proteins Bim and Bad in apoptosis of lymphocytes and platelets and in suppression of thymic lymphoma development.

Kelly PN, White MJ, Goschnick MW, Fairfax KA, Tarlinton DM, Kinkel SA, Bouillet P, Adams JM, Kile BT, Strasser A.

Cell Death Differ. 2010 Oct;17(10):1655-64. doi: 10.1038/cdd.2010.43. Epub 2010 Apr 30.

19.

IL-15 Fosters Age-Driven Regulatory T Cell Accrual in the Face of Declining IL-2 Levels.

Raynor J, Sholl A, Plas DR, Bouillet P, Chougnet CA, Hildeman DA.

Front Immunol. 2013 Jun 24;4:161. doi: 10.3389/fimmu.2013.00161. eCollection 2013.

20.
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