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Items: 1 to 20 of 148

1.

Co-ordinated role of TLR3, RIG-I and MDA5 in the innate response to rhinovirus in bronchial epithelium.

Slater L, Bartlett NW, Haas JJ, Zhu J, Message SD, Walton RP, Sykes A, Dahdaleh S, Clarke DL, Belvisi MG, Kon OM, Fujita T, Jeffery PK, Johnston SL, Edwards MR.

PLoS Pathog. 2010 Nov 4;6(11):e1001178. doi: 10.1371/journal.ppat.1001178. Erratum in: PLoS Pathog. 2012 Apr;8(4): doi/10.1371/annotation/c3f58c59-a42f-495b-a4f2-d74d55d72166.

2.

Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses.

Wang Q, Nagarkar DR, Bowman ER, Schneider D, Gosangi B, Lei J, Zhao Y, McHenry CL, Burgens RV, Miller DJ, Sajjan U, Hershenson MB.

J Immunol. 2009 Dec 1;183(11):6989-97. doi: 10.4049/jimmunol.0901386. Epub 2009 Nov 4.

3.

TLR3 and MDA5 signalling, although not expression, is impaired in asthmatic epithelial cells in response to rhinovirus infection.

Parsons KS, Hsu AC, Wark PA.

Clin Exp Allergy. 2014 Jan;44(1):91-101. doi: 10.1111/cea.12218.

PMID:
24131248
4.

MDA5 and TLR3 initiate pro-inflammatory signaling pathways leading to rhinovirus-induced airways inflammation and hyperresponsiveness.

Wang Q, Miller DJ, Bowman ER, Nagarkar DR, Schneider D, Zhao Y, Linn MJ, Goldsmith AM, Bentley JK, Sajjan US, Hershenson MB.

PLoS Pathog. 2011 May;7(5):e1002070. doi: 10.1371/journal.ppat.1002070. Epub 2011 May 26.

5.

SerpinB9 expression in human renal tubular epithelial cells is induced by triggering of the viral dsRNA sensors TLR3, MDA5 and RIG-I.

Heutinck KM, Kassies J, Florquin S, ten Berge IJ, Hamann J, Rowshani AT.

Nephrol Dial Transplant. 2012 Jul;27(7):2746-54. doi: 10.1093/ndt/gfr690. Epub 2011 Dec 13.

PMID:
22167597
6.

Rhinovirus and dsRNA induce RIG-I-like receptors and expression of interferon β and λ1 in human bronchial smooth muscle cells.

Calvén J, Yudina Y, Uller L.

PLoS One. 2013 Apr 29;8(4):e62718. doi: 10.1371/journal.pone.0062718. Print 2013.

7.

Contribution of IPS-1 to polyI:C-induced cytokine production in conjunctival epithelial cells.

Ueta M, Kawai T, Yokoi N, Akira S, Kinoshita S.

Biochem Biophys Res Commun. 2011 Jan 7;404(1):419-23. doi: 10.1016/j.bbrc.2010.11.136. Epub 2010 Dec 3.

PMID:
21130742
8.

Role of viral receptors TLR3, RIG-I and MDA5 in mesothelial tissue-type plasminogen activator and plasminogen activator inhibitor-1 synthesis.

Wörnle M, Sauter M, Kastenmüller K, Ribeiro A, Mussack T, Ladurner R, Sitter T.

Thromb Haemost. 2009 Jun;101(6):1128-37.

PMID:
19492158
9.

Viral stimuli trigger exaggerated thymic stromal lymphopoietin expression by chronic obstructive pulmonary disease epithelium: role of endosomal TLR3 and cytosolic RIG-I-like helicases.

Calvén J, Yudina Y, Hallgren O, Westergren-Thorsson G, Davies DE, Brandelius A, Uller L.

J Innate Immun. 2012;4(1):86-99. doi: 10.1159/000329131. Epub 2011 Jun 20.

PMID:
21691053
10.

Toll-like receptor 3 and RIG-I-like receptor activation induces innate antiviral responses in mouse ovarian granulosa cells.

Yan K, Zhu W, Yu L, Li N, Zhang X, Liu P, Chen Q, Chen Y, Han D.

Mol Cell Endocrinol. 2013 Jun 15;372(1-2):73-85. doi: 10.1016/j.mce.2013.03.027. Epub 2013 Apr 6.

PMID:
23567548
11.

Interaction between interferon-stimulated gene 56 and melanoma differentiation-associated gene 5 in Toll-like receptor 3 signaling in normal human mesangial cells.

Imaizumi T, Aizawa-Yashiro T, Matsumiya T, Yoshida H, Watanabe S, Tsuruga K, Tatsuta T, Xing F, Hayakari R, Meng P, Tanaka H.

Am J Nephrol. 2013;37(2):118-25. doi: 10.1159/000346415. Epub 2013 Jan 29.

PMID:
23363937
12.

RIG-I, MDA5 and TLR3 synergistically play an important role in restriction of dengue virus infection.

Nasirudeen AM, Wong HH, Thien P, Xu S, Lam KP, Liu DX.

PLoS Negl Trop Dis. 2011 Jan 4;5(1):e926. doi: 10.1371/journal.pntd.0000926.

13.

Rhinoviral stimuli, epithelial factors and ATP signalling contribute to bronchial smooth muscle production of IL-33.

Calvén J, Akbarshahi H, Menzel M, Ayata CK, Idzko M, Bjermer L, Uller L.

J Transl Med. 2015 Aug 29;13:281. doi: 10.1186/s12967-015-0645-3.

14.

DDX60, a DEXD/H box helicase, is a novel antiviral factor promoting RIG-I-like receptor-mediated signaling.

Miyashita M, Oshiumi H, Matsumoto M, Seya T.

Mol Cell Biol. 2011 Sep;31(18):3802-19. doi: 10.1128/MCB.01368-10. Epub 2011 Jul 26.

15.

MDA5 complements TLR3 in suppression of neuroblastoma.

Hsu WM, Huang CC, Lee HY, Wu PY, Wu MT, Chuang HC, Lin LL, Chuang JH.

Oncotarget. 2015 Sep 22;6(28):24935-46. doi: 10.18632/oncotarget.4511.

16.

TLR3/TRIF signalling pathway regulates IL-32 and IFN-β secretion through activation of RIP-1 and TRAF in the human cornea.

Park GB, Hur DY, Kim YS, Lee HK, Yang JW, Kim D.

J Cell Mol Med. 2015 May;19(5):1042-54. doi: 10.1111/jcmm.12495. Epub 2015 Mar 6.

17.

Novel role of toll-like receptor 3, RIG-I and MDA5 in poly (I:C) RNA-induced mesothelial inflammation.

Wörnle M, Sauter M, Kastenmüller K, Ribeiro A, Roeder M, Schmid H, Krötz F, Mussack T, Ladurner R, Sitter T.

Mol Cell Biochem. 2009 Feb;322(1-2):193-206. doi: 10.1007/s11010-008-9957-4. Epub 2008 Nov 13.

PMID:
19005739
18.

TLR3 and Rig-like receptor on myeloid dendritic cells and Rig-like receptor on human NK cells are both mandatory for production of IFN-gamma in response to double-stranded RNA.

Perrot I, Deauvieau F, Massacrier C, Hughes N, Garrone P, Durand I, Demaria O, Viaud N, Gauthier L, Blery M, Bonnefoy-Berard N, Morel Y, Tschopp J, Alexopoulou L, Trinchieri G, Paturel C, Caux C.

J Immunol. 2010 Aug 15;185(4):2080-8. doi: 10.4049/jimmunol.1000532. Epub 2010 Jul 16.

19.

Induction of interferon-λ contributes to TLR3 and RIG-I activation-mediated inhibition of herpes simplex virus type 2 replication in human cervical epithelial cells.

Zhou L, Li JL, Zhou Y, Liu JB, Zhuang K, Gao JF, Liu S, Sang M, Wu JG, Ho WZ.

Mol Hum Reprod. 2015 Dec;21(12):917-29. doi: 10.1093/molehr/gav058. Epub 2015 Oct 26.

20.

H5N1 influenza virus-induced mediators upregulate RIG-I in uninfected cells by paracrine effects contributing to amplified cytokine cascades.

Hui KP, Lee SM, Cheung CY, Mao H, Lai AK, Chan RW, Chan MC, Tu W, Guan Y, Lau YL, Peiris JS.

J Infect Dis. 2011 Dec 15;204(12):1866-78. doi: 10.1093/infdis/jir665. Epub 2011 Oct 19.

PMID:
22013225

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