Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 112


Sequence-dependent cooperative binding of p53 to DNA targets and its relationship to the structural properties of the DNA targets.

Beno I, Rosenthal K, Levitine M, Shaulov L, Haran TE.

Nucleic Acids Res. 2011 Mar;39(5):1919-32. doi: 10.1093/nar/gkq1044. Epub 2010 Nov 10.


Structural basis of DNA recognition by p53 tetramers.

Kitayner M, Rozenberg H, Kessler N, Rabinovich D, Shaulov L, Haran TE, Shakked Z.

Mol Cell. 2006 Jun 23;22(6):741-53.


High-affinity binding of tumor-suppressor protein p53 and HMGB1 to hemicatenated DNA loops.

Stros M, Muselíková-Polanská E, Pospísilová S, Strauss F.

Biochemistry. 2004 Jun 8;43(22):7215-25.


NMR spectroscopy reveals the solution dimerization interface of p53 core domains bound to their consensus DNA.

Klein C, Planker E, Diercks T, Kessler H, Künkele KP, Lang K, Hansen S, Schwaiger M.

J Biol Chem. 2001 Dec 28;276(52):49020-7. Epub 2001 Oct 17.


How p53 binds DNA as a tetramer.

McLure KG, Lee PW.

EMBO J. 1998 Jun 15;17(12):3342-50.


p53-induced DNA bending and twisting: p53 tetramer binds on the outer side of a DNA loop and increases DNA twisting.

Nagaich AK, Zhurkin VB, Durell SR, Jernigan RL, Appella E, Harrington RE.

Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):1875-80.


p53 Latency. C-terminal domain prevents binding of p53 core to target but not to nonspecific DNA sequences.

Yakovleva T, Pramanik A, Kawasaki T, Tan-No K, Gileva I, Lindegren H, Langel U, Ekstrom TJ, Rigler R, Terenius L, Bakalkin G.

J Biol Chem. 2001 May 11;276(19):15650-8. Epub 2001 Feb 23.


On the mechanism of sequence-specific DNA-dependent acetylation of p53: the acetylation motif is exposed upon DNA binding.

Cesková P, Chichger H, Wallace M, Vojtesek B, Hupp TR.

J Mol Biol. 2006 Mar 24;357(2):442-56. Epub 2005 Dec 27.


Discrimination of DNA binding sites by mutant p53 proteins.

Thukral SK, Lu Y, Blain GC, Harvey TS, Jacobsen VL.

Mol Cell Biol. 1995 Sep;15(9):5196-202.


Specific interaction of p53 with target binding sites is determined by DNA conformation and is regulated by the C-terminal domain.

Göhler T, Reimann M, Cherny D, Walter K, Warnecke G, Kim E, Deppert W.

J Biol Chem. 2002 Oct 25;277(43):41192-203. Epub 2002 Aug 8.


Architectural accommodation in the complex of four p53 DNA binding domain peptides with the p21/waf1/cip1 DNA response element.

Nagaich AK, Zhurkin VB, Sakamoto H, Gorin AA, Clore GM, Gronenborn AM, Appella E, Harrington RE.

J Biol Chem. 1997 Jun 6;272(23):14830-41.


Crystal structure of a p53 core tetramer bound to DNA.

Malecka KA, Ho WC, Marmorstein R.

Oncogene. 2009 Jan 22;28(3):325-33. doi: 10.1038/onc.2008.400. Epub 2008 Nov 3.


High thermostability and lack of cooperative DNA binding distinguish the p63 core domain from the homologous tumor suppressor p53.

Klein C, Georges G, Künkele KP, Huber R, Engh RA, Hansen S.

J Biol Chem. 2001 Oct 5;276(40):37390-401. Epub 2001 Jul 26.


Crystal structure of the p53 core domain bound to a full consensus site as a self-assembled tetramer.

Chen Y, Dey R, Chen L.

Structure. 2010 Feb 10;18(2):246-56. doi: 10.1016/j.str.2009.11.011.


Sequence-dependent sliding kinetics of p53.

Leith JS, Tafvizi A, Huang F, Uspal WE, Doyle PS, Fersht AR, Mirny LA, van Oijen AM.

Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16552-7. doi: 10.1073/pnas.1120452109. Epub 2012 Sep 25.


Structures of p63 DNA binding domain in complexes with half-site and with spacer-containing full response elements.

Chen C, Gorlatova N, Kelman Z, Herzberg O.

Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6456-61. doi: 10.1073/pnas.1013657108. Epub 2011 Apr 4.


Structure of the p53 core domain dimer bound to DNA.

Ho WC, Fitzgerald MX, Marmorstein R.

J Biol Chem. 2006 Jul 21;281(29):20494-502. Epub 2006 May 22.

Supplemental Content

Support Center