Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 163


Bcl-2 proteins and mitochondria--specificity in membrane targeting for death.

Lindsay J, Esposti MD, Gilmore AP.

Biochim Biophys Acta. 2011 Apr;1813(4):532-9. doi: 10.1016/j.bbamcr.2010.10.017. Epub 2010 Nov 5. Review.


BimS-induced apoptosis requires mitochondrial localization but not interaction with anti-apoptotic Bcl-2 proteins.

Weber A, Paschen SA, Heger K, Wilfling F, Frankenberg T, Bauerschmitt H, Seiffert BM, Kirschnek S, Wagner H, Häcker G.

J Cell Biol. 2007 May 21;177(4):625-36.


BH3-only proteins: Orchestrators of apoptosis.

Shamas-Din A, Brahmbhatt H, Leber B, Andrews DW.

Biochim Biophys Acta. 2011 Apr;1813(4):508-20. doi: 10.1016/j.bbamcr.2010.11.024. Epub 2010 Dec 10. Review.


Apoptogenic factors released from mitochondria.

Vaux DL.

Biochim Biophys Acta. 2011 Apr;1813(4):546-50. doi: 10.1016/j.bbamcr.2010.08.002. Epub 2010 Aug 14. Review.


Examining BCL-2 family function with large unilamellar vesicles.

Asciolla JJ, Renault TT, Chipuk JE.

J Vis Exp. 2012 Oct 5;(68). pii: 4291. doi: 10.3791/4291.


The deadly landscape of pro-apoptotic BCL-2 proteins in the outer mitochondrial membrane.

Luna-Vargas MP, Chipuk JE.

FEBS J. 2016 Jul;283(14):2676-89. doi: 10.1111/febs.13624. Epub 2016 Jan 6. Review.


Mitochondrial membrane permeabilisation by Bax/Bak.

Degli Esposti M, Dive C.

Biochem Biophys Res Commun. 2003 May 9;304(3):455-61. Review.


How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

Chipuk JE, Green DR.

Trends Cell Biol. 2008 Apr;18(4):157-64. doi: 10.1016/j.tcb.2008.01.007. Epub 2008 Mar 7. Review.


Apoptosis regulation at the mitochondrial outer membrane.

Gillies LA, Kuwana T.

J Cell Biochem. 2014 Apr;115(4):632-40. doi: 10.1002/jcb.24709. Review.


Direct addition of BimL to mitochondria does not lead to cytochrome c release.

Terradillos O, Montessuit S, Huang DC, Martinou JC.

FEBS Lett. 2002 Jul 3;522(1-3):29-34.


BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis.

Cheng EH, Wei MC, Weiler S, Flavell RA, Mak TW, Lindsten T, Korsmeyer SJ.

Mol Cell. 2001 Sep;8(3):705-11.


In non-transformed cells Bak activates upon loss of anti-apoptotic Bcl-XL and Mcl-1 but in the absence of active BH3-only proteins.

Senft D, Weber A, Saathoff F, Berking C, Heppt MV, Kammerbauer C, Rothenfusser S, Kellner S, Kurgyis Z, Besch R, Häcker G.

Cell Death Dis. 2015 Nov 26;6:e1996. doi: 10.1038/cddis.2015.341.


BH3-only proteins and their roles in programmed cell death.

Giam M, Huang DC, Bouillet P.

Oncogene. 2008 Dec;27 Suppl 1:S128-36. doi: 10.1038/onc.2009.50. Review.


Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit is collaboration with pro-apoptotic Bak or Bax.

Werner AB, de Vries E, Tait SW, Bontjer I, Borst J.

J Biol Chem. 2002 Jun 21;277(25):22781-8. Epub 2002 Apr 19.


BAK/BAX activation and cytochrome c release assays using isolated mitochondria.

Renault TT, Floros KV, Chipuk JE.

Methods. 2013 Jun 1;61(2):146-55. doi: 10.1016/j.ymeth.2013.03.030. Epub 2013 Apr 6.


At the gates of death.

Green DR.

Cancer Cell. 2006 May;9(5):328-30.


An interconnected hierarchical model of cell death regulation by the BCL-2 family.

Chen HC, Kanai M, Inoue-Yamauchi A, Tu HC, Huang Y, Ren D, Kim H, Takeda S, Reyna DE, Chan PM, Ganesan YT, Liao CP, Gavathiotis E, Hsieh JJ, Cheng EH.

Nat Cell Biol. 2015 Oct;17(10):1270-81. doi: 10.1038/ncb3236. Epub 2015 Sep 7.


Discoveries and controversies in BCL-2 protein-mediated apoptosis.

Zheng JH, Viacava Follis A, Kriwacki RW, Moldoveanu T.

FEBS J. 2016 Jul;283(14):2690-700. doi: 10.1111/febs.13527. Epub 2015 Oct 27. Review.


The multidomain proapoptotic molecules Bax and Bak are directly activated by heat.

Pagliari LJ, Kuwana T, Bonzon C, Newmeyer DD, Tu S, Beere HM, Green DR.

Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):17975-80. Epub 2005 Dec 5.

Supplemental Content

Support Center