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A recombination hotspot leads to sequence variability within a novel gene (AK005651) and contributes to type 1 diabetes susceptibility.

Tan IK, Mackin L, Wang N, Papenfuss AT, Elso CM, Ashton MP, Quirk F, Phipson B, Bahlo M, Speed TP, Smyth GK, Morahan G, Brodnicki TC.

Genome Res. 2010 Dec;20(12):1629-38. doi: 10.1101/gr.101881.109. Epub 2010 Nov 4.


Congenic mapping of the type 1 diabetes locus, Idd3, to a 780-kb region of mouse chromosome 3: identification of a candidate segment of ancestral DNA by haplotype mapping.

Lyons PA, Armitage N, Argentina F, Denny P, Hill NJ, Lord CJ, Wilusz MB, Peterson LB, Wicker LS, Todd JA.

Genome Res. 2000 Apr;10(4):446-53.


Localization of Idd11 using NOD congenic mouse strains: elimination of Slc9a1 as a candidate gene.

Brodnicki TC, McClive P, Couper S, Morahan G.

Immunogenetics. 2000 Jan;51(1):37-41.


Localization of Idd11 is not associated with thymus and nkt cell abnormalities in NOD mice.

Brodnicki TC, Fletcher AL, Pellicci DG, Berzins SP, McClive P, Quirk F, Webster KE, Scott HS, Boyd RL, Godfrey DI, Morahan G.

Diabetes. 2005 Dec;54(12):3453-7.


Congenic mapping and candidate sequencing of susceptibility genes for Type 1 diabetes in the NOD mouse.

Ikegami H, Fujisawa T, Makino S, Ogihara T.

Ann N Y Acad Sci. 2003 Nov;1005:196-204.


Genetic dissection of type 1 diabetes susceptibility gene, Idd3, by ancestral haplotype congenic mapping.

Ikegami H, Fujisawa T, Makino S, Ogihara T.

Ann N Y Acad Sci. 2002 Apr;958:325-8.


Molecular genetic analysis of the Idd4 locus implicates the IFN response in type 1 diabetes susceptibility in nonobese diabetic mice.

Ivakine EA, Gulban OM, Mortin-Toth SM, Wankiewicz E, Scott C, Spurrell D, Canty A, Danska JS.

J Immunol. 2006 Mar 1;176(5):2976-90.


The idd4 locus displays sex-specific epistatic effects on type 1 diabetes susceptibility in nonobese diabetic mice.

Ivakine EA, Mortin-Toth SM, Gulban OM, Valova A, Canty A, Scott C, Danska JS.

Diabetes. 2006 Dec;55(12):3611-9.


Identification of a structurally distinct CD101 molecule encoded in the 950-kb Idd10 region of NOD mice.

Penha-Gonçalves C, Moule C, Smink LJ, Howson J, Gregory S, Rogers J, Lyons PA, Suttie JJ, Lord CJ, Peterson LB, Todd JA, Wicker LS.

Diabetes. 2003 Jun;52(6):1551-6.


Identification of the inflammasome Nlrp1b as the candidate gene conferring diabetes risk at the Idd4.1 locus in the nonobese diabetic mouse.

Motta VN, Markle JG, Gulban O, Mortin-Toth S, Liao KC, Mogridge J, Steward CA, Danska JS.

J Immunol. 2015 Jun 15;194(12):5663-73. doi: 10.4049/jimmunol.1400913. Epub 2015 May 11.


Crosses of NOD mice with the related NON strain. A polygenic model for IDDM.

McAleer MA, Reifsnyder P, Palmer SM, Prochazka M, Love JM, Copeman JB, Powell EE, Rodrigues NR, Prins JB, Serreze DV, et al.

Diabetes. 1995 Oct;44(10):1186-95.


Sex-specific effect of insulin-dependent diabetes 4 on regulation of diabetes pathogenesis in the nonobese diabetic mouse.

Ivakine EA, Fox CJ, Paterson AD, Mortin-Toth SM, Canty A, Walton DS, Aleksa K, Ito S, Danska JS.

J Immunol. 2005 Jun 1;174(11):7129-40.


Subcongenic analyses reveal complex interactions between distal chromosome 4 genes controlling diabetogenic B cells and CD4 T cells in nonobese diabetic mice.

Stolp J, Chen YG, Cox SL, Henck V, Zhang W, Tsaih SW, Chapman H, Stearns T, Serreze DV, Silveira PA.

J Immunol. 2012 Aug 1;189(3):1406-17. doi: 10.4049/jimmunol.1200120. Epub 2012 Jun 25.


Sequence analysis of candidate genes for common susceptibility to type 1 and type 2 diabetes in mice.

Yamada K, Ikegami H, Kawaguchi Y, Fujisawa T, Hotta M, Ueda H, Shintani M, Nojima K, Kawabata Y, Ono M, Nishino M, Itoi M, Babaya N, Shibata M, Makino S, Ogihara T.

Endocr J. 2001 Apr;48(2):241-7.


Use of recombinant congenic and congenic strains of NOD mice to identify a new insulin-dependent diabetes resistance gene.

Serreze DV, Prochazka M, Reifsnyder PC, Bridgett MM, Leiter EH.

J Exp Med. 1994 Oct 1;180(4):1553-8.


MHC-linked diabetogenic gene of the NOD mouse: molecular mapping of the 3' boundary of the diabetogenic region.

Ikegami H, Kawaguchi Y, Ueda H, Fukuda M, Takakawa K, Fujioka Y, Fujisawa T, Uchida K, Ogihara T.

Biochem Biophys Res Commun. 1993 Apr 30;192(2):677-82.


Congenic mapping identifies a novel Idd9 subregion regulating type 1 diabetes in NOD mice.

Lin B, Ciecko AE, MacKinney E, Serreze DV, Chen YG.

Immunogenetics. 2017 Mar;69(3):193-198. doi: 10.1007/s00251-016-0957-3. Epub 2016 Oct 28.


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