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Items: 1 to 20 of 85

1.

A high-throughput screening strategy to overcome virus instability.

Rasmussen L, Maddox C, Moore BP, Severson W, White EL.

Assay Drug Dev Technol. 2011 Apr;9(2):184-90. doi: 10.1089/adt.2010.0298. Epub 2010 Nov 4.

2.

A Phenotypic High-Throughput Screen with RSV-Infected Primary Human Small Airway Epithelial Cells (SAECs).

Gobel J, Gartland M, Gurley SH, Kadwell S, Gillie D, Moore C, Goetz A.

J Biomol Screen. 2015 Jul;20(6):729-38. doi: 10.1177/1087057115580271. Epub 2015 Apr 10.

PMID:
25862685
3.

A cell based high-throughput screening approach for the discovery of new inhibitors of respiratory syncytial virus.

Chung DH, Moore BP, Matharu DS, Golden JE, Maddox C, Rasmussen L, Sosa MI, Ananthan S, White EL, Jia F, Jonsson CB, Severson WE.

Virol J. 2013 Jan 10;10:19. doi: 10.1186/1743-422X-10-19.

4.

Novel diversity-oriented synthesis-derived respiratory syncytial virus inhibitors identified via a high throughput replicon-based screen.

Duvall JR, VerPlank L, Ludeke B, McLeod SM, Lee MD 4th, Vishwanathan K, Mulrooney CA, Le Quement S, Yu Q, Palmer MA, Fleming P, Fearns R, Foley MA, Scherer CA.

Antiviral Res. 2016 Jul;131:19-25. doi: 10.1016/j.antiviral.2016.03.015. Epub 2016 Apr 6.

5.

Cyclopiazonic acid, an inhibitor of calcium-dependent ATPases with antiviral activity against human respiratory syncytial virus.

Cui R, Wang Y, Wang L, Li G, Lan K, Altmeyer R, Zou G.

Antiviral Res. 2016 Aug;132:38-45. doi: 10.1016/j.antiviral.2016.05.010. Epub 2016 May 17.

PMID:
27210812
6.

Antiviral effect of cimicifugin from Cimicifuga foetida against human respiratory syncytial virus.

Wang KC, Chang JS, Lin LT, Chiang LC, Lin CC.

Am J Chin Med. 2012;40(5):1033-45. doi: 10.1142/S0192415X12500760.

PMID:
22928833
7.

A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of Human Respiratory Syncytial Virus.

Ouizougun-Oubari M, Pereira N, Tarus B, Galloux M, Lassoued S, Fix J, Tortorici MA, Hoos S, Baron B, England P, Desmaële D, Couvreur P, Bontems F, Rey FA, Eléouët JF, Sizun C, Slama-Schwok A, Duquerroy S.

J Virol. 2015 Nov;89(21):11129-43. doi: 10.1128/JVI.01612-15. Epub 2015 Aug 5.

8.

Replication-Competent Influenza Virus and Respiratory Syncytial Virus Luciferase Reporter Strains Engineered for Co-Infections Identify Antiviral Compounds in Combination Screens.

Yan D, Weisshaar M, Lamb K, Chung HK, Lin MZ, Plemper RK.

Biochemistry. 2015 Sep 15;54(36):5589-604. doi: 10.1021/acs.biochem.5b00623. Epub 2015 Sep 1.

9.

Characterization of novel respiratory syncytial virus inhibitors identified by high throughput screen.

Laganas VA, Dunn EF, McLaughlin RE, Tiong-Yip CL, Yuzhakov O, Isabella VM, Hill P, Yu Q.

Antiviral Res. 2015 Mar;115:71-4. doi: 10.1016/j.antiviral.2014.12.012. Epub 2014 Dec 24.

PMID:
25542974
10.

Two novel fusion inhibitors of human respiratory syncytial virus.

Lundin A, Bergström T, Bendrioua L, Kann N, Adamiak B, Trybala E.

Antiviral Res. 2010 Dec;88(3):317-24. doi: 10.1016/j.antiviral.2010.10.004. Epub 2010 Oct 19.

PMID:
20965215
11.

High-Throughput Hit Screening Cascade to Identify Respiratory Syncytial Virus (RSV) Inhibitors.

Plant H, Stacey C, Tiong-Yip CL, Walsh J, Yu Q, Rich K.

J Biomol Screen. 2015 Jun;20(5):597-605. doi: 10.1177/1087057115569428. Epub 2015 Feb 5.

PMID:
25656237
12.

Screening and evaluation of anti-respiratory syncytial virus compounds in cultured cells.

Lundin A, Bergström T, Trybala E.

Methods Mol Biol. 2013;1030:345-63. doi: 10.1007/978-1-62703-484-5_27.

PMID:
23821281
13.

Discovery of methylsulfonyl indazoles as potent and orally active respiratory syncytial Virus(RSV) fusion inhibitors.

Feng S, Li C, Chen D, Zheng X, Yun H, Gao L, Shen HC.

Eur J Med Chem. 2017 Sep 29;138:1147-1157. doi: 10.1016/j.ejmech.2017.07.032. Epub 2017 Jul 20.

PMID:
28772235
14.

High-throughput screening of stabilizers for respiratory syncytial virus: identification of stabilizers and their effects on the conformational thermostability of viral particles.

Ausar SF, Espina M, Brock J, Thyagarayapuran N, Repetto R, Khandke L, Middaugh CR.

Hum Vaccin. 2007 May-Jun;3(3):94-103. Epub 2007 May 15.

PMID:
17426457
15.

Respiratory syncytial virus infections: recent prospects for control.

Sidwell RW, Barnard DL.

Antiviral Res. 2006 Sep;71(2-3):379-90. Epub 2006 Jun 9. Review.

PMID:
16806515
16.

Respiratory syncytial virus infection in adult populations.

Walsh EE, Falsey AR.

Infect Disord Drug Targets. 2012 Apr;12(2):98-102. Review.

PMID:
22335500
17.

Identification of broad-spectrum antiviral compounds and assessment of the druggability of their target for efficacy against respiratory syncytial virus (RSV).

Bonavia A, Franti M, Pusateri Keaney E, Kuhen K, Seepersaud M, Radetich B, Shao J, Honda A, Dewhurst J, Balabanis K, Monroe J, Wolff K, Osborne C, Lanieri L, Hoffmaster K, Amin J, Markovits J, Broome M, Skuba E, Cornella-Taracido I, Joberty G, Bouwmeester T, Hamann L, Tallarico JA, Tommasi R, Compton T, Bushell SM.

Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6739-44. doi: 10.1073/pnas.1017142108. Epub 2011 Apr 18.

18.

A fluorescence-based high-throughput antiviral compound screening assay against respiratory syncytial virus.

Kwanten L, De Clerck B, Roymans D.

Methods Mol Biol. 2013;1030:337-44. doi: 10.1007/978-1-62703-484-5_26.

PMID:
23821280
19.

Novel therapies for an old virus: treatment of RSV infections in the 21st Century.

Lüsebrink J, Schildgen V, Schildgen O.

Expert Rev Anti Infect Ther. 2009 Nov;7(9):1125-9. doi: 10.1586/eri.09.90. Review.

PMID:
19883332
20.

Development of a reverse genetics system for respiratory syncytial virus long strain and an immunogenicity study of the recombinant virus.

Hu B, Jiang J, Zhan J, Li G, Jiang Y, Guan X, Chen Y, Fang Z.

Virol J. 2014 Aug 8;11:142. doi: 10.1186/1743-422X-11-142.

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