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Items: 1 to 20 of 121

1.

Upf1 senses 3'UTR length to potentiate mRNA decay.

Hogg JR, Goff SP.

Cell. 2010 Oct 29;143(3):379-89. doi: 10.1016/j.cell.2010.10.005.

2.

Polypyrimidine tract binding protein 1 protects mRNAs from recognition by the nonsense-mediated mRNA decay pathway.

Ge Z, Quek BL, Beemon KL, Hogg JR.

Elife. 2016 Jan 8;5. pii: e11155. doi: 10.7554/eLife.11155.

3.

Transcripts expressed using a bicistronic vector pIREShyg2 are sensitized to nonsense-mediated mRNA decay.

Shikama Y, Hu H, Ohno M, Matsuoka I, Shichishima T, Kimura J.

BMC Mol Biol. 2010 Jun 1;11:42. doi: 10.1186/1471-2199-11-42.

4.

Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay.

Kim YK, Furic L, Desgroseillers L, Maquat LE.

Cell. 2005 Jan 28;120(2):195-208.

5.

Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay.

Isken O, Kim YK, Hosoda N, Mayeur GL, Hershey JW, Maquat LE.

Cell. 2008 Apr 18;133(2):314-27. doi: 10.1016/j.cell.2008.02.030.

6.

Upf1 ATPase-dependent mRNP disassembly is required for completion of nonsense- mediated mRNA decay.

Franks TM, Singh G, Lykke-Andersen J.

Cell. 2010 Dec 10;143(6):938-50. doi: 10.1016/j.cell.2010.11.043.

7.

Inter-kingdom conservation of mechanism of nonsense-mediated mRNA decay.

Kerényi Z, Mérai Z, Hiripi L, Benkovics A, Gyula P, Lacomme C, Barta E, Nagy F, Silhavy D.

EMBO J. 2008 Jun 4;27(11):1585-95. doi: 10.1038/emboj.2008.88. Epub 2008 May 1.

8.

A post-translational regulatory switch on UPF1 controls targeted mRNA degradation.

Kurosaki T, Li W, Hoque M, Popp MW, Ermolenko DN, Tian B, Maquat LE.

Genes Dev. 2014 Sep 1;28(17):1900-16. doi: 10.1101/gad.245506.114.

9.

A position-specific 3'UTR sequence that accelerates mRNA decay.

Geissler R, Grimson A.

RNA Biol. 2016 Nov;13(11):1075-1077. Epub 2016 Aug 26. Review.

10.

Expression proteomics of UPF1 knockdown in HeLa cells reveals autoregulation of hnRNP A2/B1 mediated by alternative splicing resulting in nonsense-mediated mRNA decay.

McGlincy NJ, Tan LY, Paul N, Zavolan M, Lilley KS, Smith CW.

BMC Genomics. 2010 Oct 14;11:565. doi: 10.1186/1471-2164-11-565.

11.

Translational regulation of GluR2 mRNAs in rat hippocampus by alternative 3' untranslated regions.

Irier HA, Shaw R, Lau A, Feng Y, Dingledine R.

J Neurochem. 2009 Apr;109(2):584-94. doi: 10.1111/j.1471-4159.2009.05992.x. Epub 2009 Feb 13.

12.

Evidence that the Upf1-related molecular motor scans the 3'-UTR to ensure mRNA integrity.

Shigeoka T, Kato S, Kawaichi M, Ishida Y.

Nucleic Acids Res. 2012 Aug;40(14):6887-97. doi: 10.1093/nar/gks344. Epub 2012 May 2.

13.

Upf1/Upf2 regulation of 3' untranslated region splice variants of AUF1 links nonsense-mediated and A+U-rich element-mediated mRNA decay.

Banihashemi L, Wilson GM, Das N, Brewer G.

Mol Cell Biol. 2006 Dec;26(23):8743-54. Epub 2006 Sep 25.

14.

Rules that govern UPF1 binding to mRNA 3' UTRs.

Kurosaki T, Maquat LE.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3357-62. doi: 10.1073/pnas.1219908110. Epub 2013 Feb 12.

15.

Global analyses of UPF1 binding and function reveal expanded scope of nonsense-mediated mRNA decay.

Hurt JA, Robertson AD, Burge CB.

Genome Res. 2013 Oct;23(10):1636-50. doi: 10.1101/gr.157354.113. Epub 2013 Jun 13.

16.

The role of nucleotide composition in premature termination codon recognition.

Zahdeh F, Carmel L.

BMC Bioinformatics. 2016 Dec 7;17(1):519.

17.

Target Discrimination in Nonsense-Mediated mRNA Decay Requires Upf1 ATPase Activity.

Lee SR, Pratt GA, Martinez FJ, Yeo GW, Lykke-Andersen J.

Mol Cell. 2015 Aug 6;59(3):413-25. doi: 10.1016/j.molcel.2015.06.036.

18.

UPF1 association with the cap-binding protein, CBP80, promotes nonsense-mediated mRNA decay at two distinct steps.

Hwang J, Sato H, Tang Y, Matsuda D, Maquat LE.

Mol Cell. 2010 Aug 13;39(3):396-409. doi: 10.1016/j.molcel.2010.07.004. Epub 2010 Aug 5.

19.

Stability of plant mRNAs depends on the length of the 3'-untranslated region.

Schwartz AM, Komarova TV, Skulachev MV, Zvereva AS, Dorokhov IuL, Atabekov JG.

Biochemistry (Mosc). 2006 Dec;71(12):1377-84.

PMID:
17223792
20.

Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay.

Kashima I, Yamashita A, Izumi N, Kataoka N, Morishita R, Hoshino S, Ohno M, Dreyfuss G, Ohno S.

Genes Dev. 2006 Feb 1;20(3):355-67.

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