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Items: 1 to 20 of 73

1.

Matching models to data: a receptor pharmacologist's guide.

Hall DA, Langmead CJ.

Br J Pharmacol. 2010 Nov;161(6):1276-90. doi: 10.1111/j.1476-5381.2010.00879.x. Review.

2.

Elusive equilibrium: the challenge of interpreting receptor pharmacology using calcium assays.

Charlton SJ, Vauquelin G.

Br J Pharmacol. 2010 Nov;161(6):1250-65. doi: 10.1111/j.1476-5381.2010.00863.x. Review.

3.

Use of the GTPγS ([35S]GTPγS and Eu-GTPγS) binding assay for analysis of ligand potency and efficacy at G protein-coupled receptors.

Strange PG.

Br J Pharmacol. 2010 Nov;161(6):1238-49. doi: 10.1111/j.1476-5381.2010.00963.x. Review.

4.

So what do we call GPR18 now?

Alexander SP.

Br J Pharmacol. 2012 Apr;165(8):2411-3. doi: 10.1111/j.1476-5381.2011.01731.x.

5.

Estimation of the dissociation rate of unlabelled ligand-receptor complexes by a 'two-step' competition binding approach.

Packeu A, Wennerberg M, Balendran A, Vauquelin G.

Br J Pharmacol. 2010 Nov;161(6):1311-28. doi: 10.1111/j.1476-5381.2010.00931.x.

6.

Optimising in vivo pharmacology studies--Practical PKPD considerations.

Gabrielsson J, Green AR, Van der Graaf PH.

J Pharmacol Toxicol Methods. 2010 Mar-Apr;61(2):146-56. doi: 10.1016/j.vascn.2010.02.002. Epub 2010 Feb 11. Review.

PMID:
20153442
7.

Analysis of the actions of the novel dopamine receptor-directed compounds (S)-OSU6162 and ACR16 at the D2 dopamine receptor.

Kara E, Lin H, Svensson K, Johansson AM, Strange PG.

Br J Pharmacol. 2010 Nov;161(6):1343-50. doi: 10.1111/j.1476-5381.2010.01010.x.

8.

The impact of scientific models on clinical psychopharmacology: a pharmacologist's view.

Lasagna L.

Semin Psychiatry. 1972 Aug;4(3):271-82. No abstract available.

PMID:
4680225
9.

Modeling promiscuity based on in vitro safety pharmacology profiling data.

Azzaoui K, Hamon J, Faller B, Whitebread S, Jacoby E, Bender A, Jenkins JL, Urban L.

ChemMedChem. 2007 Jun;2(6):874-80.

PMID:
17492703
10.

GPR18 in microglia: implications for the CNS and endocannabinoid system signalling.

McHugh D.

Br J Pharmacol. 2012 Dec;167(8):1575-82. doi: 10.1111/j.1476-5381.2012.02019.x. Review.

11.

Themed section: endothelin.

Davenport AP, Barton M.

Br J Pharmacol. 2013 Jan;168(2):279-82. doi: 10.1111/bph.12022.

12.

Fluorescence- and bioluminescence-based approaches to study GPCR ligand binding.

Stoddart LA, White CW, Nguyen K, Hill SJ, Pfleger KD.

Br J Pharmacol. 2016 Oct;173(20):3028-37. doi: 10.1111/bph.13316. Epub 2015 Nov 5.

13.
14.

Quantitative pharmacology or pharmacokinetic pharmacodynamic integration should be a vital component in integrative pharmacology.

Gabrielsson J, Green AR.

J Pharmacol Exp Ther. 2009 Dec;331(3):767-74. doi: 10.1124/jpet.109.157172. Epub 2009 Sep 24. Review.

15.

Methodological innovations expand the safety pharmacology horizon.

Pugsley MK, Curtis MJ.

J Pharmacol Toxicol Methods. 2012 Sep;66(2):59-62. doi: 10.1016/j.vascn.2012.05.004. Epub 2012 May 20.

PMID:
22617368
16.

Estimation of agonist affinity and efficacy by direct, operational model-fitting.

Leff P, Prentice DJ, Giles H, Martin GR, Wood J.

J Pharmacol Methods. 1990 May;23(3):225-37.

PMID:
2329803
17.

The fall and rise of pharmacology--(re-)defining the discipline?

Winquist RJ, Mullane K, Williams M.

Biochem Pharmacol. 2014 Jan 1;87(1):4-24. doi: 10.1016/j.bcp.2013.09.011. Epub 2013 Sep 23. Review.

PMID:
24070656
18.

Wooldridge Memorial lecture. Pharmacology and new drug discoveries--should veterinarians be interested?

Black J.

Vet Rec. 1984 Nov 3;115(18):466-70. No abstract available.

PMID:
6506443
19.

Molecular pharmacology of G protein-coupled receptors.

Summers RJ.

Br J Pharmacol. 2016 Oct;173(20):2931-3. doi: 10.1111/bph.13610.

PMID:
27682321
20.

Minimizing metabolic activation during pharmaceutical lead optimization: progress, knowledge gaps and future directions.

Kumar S, Kassahun K, Tschirret-Guth RA, Mitra K, Baillie TA.

Curr Opin Drug Discov Devel. 2008 Jan;11(1):43-52. Review.

PMID:
18175266

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