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Items: 1 to 20 of 105

1.

Non-bulk-like solvent behavior in the ribosome exit tunnel.

Lucent D, Snow CD, Aitken CE, Pande VS.

PLoS Comput Biol. 2010 Oct 21;6(10):e1000963. doi: 10.1371/journal.pcbi.1000963.

2.

Side-chain recognition and gating in the ribosome exit tunnel.

Petrone PM, Snow CD, Lucent D, Pande VS.

Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16549-54. doi: 10.1073/pnas.0801795105. Epub 2008 Oct 22.

3.

The geometry of the ribosomal polypeptide exit tunnel.

Voss NR, Gerstein M, Steitz TA, Moore PB.

J Mol Biol. 2006 Jul 21;360(4):893-906. Epub 2006 May 30.

PMID:
16784753
4.

Cotranslational Protein Folding inside the Ribosome Exit Tunnel.

Nilsson OB, Hedman R, Marino J, Wickles S, Bischoff L, Johansson M, Müller-Lucks A, Trovato F, Puglisi JD, O'Brien EP, Beckmann R, von Heijne G.

Cell Rep. 2015 Sep 8;12(10):1533-40. doi: 10.1016/j.celrep.2015.07.065. Epub 2015 Aug 28.

5.

Trigger factor in complex with the ribosome forms a molecular cradle for nascent proteins.

Ferbitz L, Maier T, Patzelt H, Bukau B, Deuerling E, Ban N.

Nature. 2004 Sep 30;431(7008):590-6. Epub 2004 Aug 29.

PMID:
15334087
6.

The ribosomal tunnel as a functional environment for nascent polypeptide folding and translational stalling.

Wilson DN, Beckmann R.

Curr Opin Struct Biol. 2011 Apr;21(2):274-82. doi: 10.1016/j.sbi.2011.01.007. Review.

PMID:
21316217
7.

Statics of the ribosomal exit tunnel: implications for cotranslational peptide folding, elongation regulation, and antibiotics binding.

Fulle S, Gohlke H.

J Mol Biol. 2009 Mar 27;387(2):502-17. doi: 10.1016/j.jmb.2009.01.037. Epub 2009 Jan 27.

PMID:
19356596
8.

A crevice adjoining the ribosome tunnel: hints for cotranslational folding.

Amit M, Berisio R, Baram D, Harms J, Bashan A, Yonath A.

FEBS Lett. 2005 Jun 13;579(15):3207-13. Epub 2005 Mar 23.

9.

alpha-Helical nascent polypeptide chains visualized within distinct regions of the ribosomal exit tunnel.

Bhushan S, Gartmann M, Halic M, Armache JP, Jarasch A, Mielke T, Berninghausen O, Wilson DN, Beckmann R.

Nat Struct Mol Biol. 2010 Mar;17(3):313-7. doi: 10.1038/nsmb.1756. Epub 2010 Feb 7.

PMID:
20139981
10.

Transient tertiary structure formation within the ribosome exit port.

O'Brien EP, Hsu ST, Christodoulou J, Vendruscolo M, Dobson CM.

J Am Chem Soc. 2010 Dec 1;132(47):16928-37. doi: 10.1021/ja106530y. Epub 2010 Nov 9.

PMID:
21062068
11.

Confined dynamics of a ribosome-bound nascent globin: Cone angle analysis of fluorescence depolarization decays in the presence of two local motions.

Ellis JP, Culviner PH, Cavagnero S.

Protein Sci. 2009 Oct;18(10):2003-15. doi: 10.1002/pro.196. Erratum in: Protein Sci. 2010 Aug;19(8):1600.

12.

Macrolide-peptide conjugates as probes of the path of travel of the nascent peptides through the ribosome.

Washington AZ, Benicewicz DB, Canzoneri JC, Fagan CE, Mwakwari SC, Maehigashi T, Dunham CM, Oyelere AK.

ACS Chem Biol. 2014 Nov 21;9(11):2621-31. doi: 10.1021/cb5003224. Epub 2014 Sep 22.

13.

The ribosome and its role in protein folding: looking through a magnifying glass.

Javed A, Christodoulou J, Cabrita LD, Orlova EV.

Acta Crystallogr D Struct Biol. 2017 Jun 1;73(Pt 6):509-521. doi: 10.1107/S2059798317007446. Epub 2017 May 31. Review.

14.

Interaction of nascent chains with the ribosomal tunnel proteins Rpl4, Rpl17, and Rpl39 of Saccharomyces cerevisiae.

Zhang Y, Wölfle T, Rospert S.

J Biol Chem. 2013 Nov 22;288(47):33697-707. doi: 10.1074/jbc.M113.508283. Epub 2013 Sep 26.

15.

Conjugates of amino acids and peptides with 5-o-mycaminosyltylonolide and their interaction with the ribosomal exit tunnel.

Shishkina A, Makarov G, Tereshchenkov A, Korshunova G, Sumbatyan N, Golovin A, Svetlov M, Bogdanov A.

Bioconjug Chem. 2013 Nov 20;24(11):1861-9. doi: 10.1021/bc400236n. Epub 2013 Oct 25.

PMID:
24090034
16.

Macrolide antibiotics allosterically predispose the ribosome for translation arrest.

Sothiselvam S, Liu B, Han W, Ramu H, Klepacki D, Atkinson GC, Brauer A, Remm M, Tenson T, Schulten K, Vázquez-Laslop N, Mankin AS.

Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9804-9. doi: 10.1073/pnas.1403586111. Epub 2014 Jun 24.

17.

Computational evidence that fast translation speed can increase the probability of cotranslational protein folding.

Wang E, Wang J, Chen C, Xiao Y.

Sci Rep. 2015 Oct 21;5:15316. doi: 10.1038/srep15316.

18.

Kinetic analysis of ribosome-bound fluorescent proteins reveals an early, stable, cotranslational folding intermediate.

Kelkar DA, Khushoo A, Yang Z, Skach WR.

J Biol Chem. 2012 Jan 20;287(4):2568-78. doi: 10.1074/jbc.M111.318766. Epub 2011 Nov 28.

19.

Effect of Nascent Peptide Steric Bulk on Elongation Kinetics in the Ribosome Exit Tunnel.

Po P, Delaney E, Gamper H, Szantai-Kis DM, Speight L, Tu L, Kosolapov A, Petersson EJ, Hou YM, Deutsch C.

J Mol Biol. 2017 Jun 16;429(12):1873-1888. doi: 10.1016/j.jmb.2017.04.019. Epub 2017 May 5.

PMID:
28483649
20.

Negamycin binds to the wall of the nascent chain exit tunnel of the 50S ribosomal subunit.

Schroeder SJ, Blaha G, Moore PB.

Antimicrob Agents Chemother. 2007 Dec;51(12):4462-5. Epub 2007 Jul 30.

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