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Items: 1 to 20 of 114

1.

Mouse CD8alpha+ DCs and human BDCA3+ DCs are major producers of IFN-lambda in response to poly IC.

Lauterbach H, Bathke B, Gilles S, Traidl-Hoffmann C, Luber CA, Fejer G, Freudenberg MA, Davey GM, Vremec D, Kallies A, Wu L, Shortman K, Chaplin P, Suter M, O'Keeffe M, Hochrein H.

J Exp Med. 2010 Nov 22;207(12):2703-17. doi: 10.1084/jem.20092720.

2.

Human blood dendritic cell antigen 3 (BDCA3)(+) dendritic cells are a potent producer of interferon-λ in response to hepatitis C virus.

Yoshio S, Kanto T, Kuroda S, Matsubara T, Higashitani K, Kakita N, Ishida H, Hiramatsu N, Nagano H, Sugiyama M, Murata K, Fukuhara T, Matsuura Y, Hayashi N, Mizokami M, Takehara T.

Hepatology. 2013 May;57(5):1705-15. doi: 10.1002/hep.26182.

PMID:
23213063
3.

ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells.

Schiavoni G, Mattei F, Sestili P, Borghi P, Venditti M, Morse HC 3rd, Belardelli F, Gabriele L.

J Exp Med. 2002 Dec 2;196(11):1415-25.

4.

Poly I:C-induced activation of NK cells by CD8 alpha+ dendritic cells via the IPS-1 and TRIF-dependent pathways.

Miyake T, Kumagai Y, Kato H, Guo Z, Matsushita K, Satoh T, Kawagoe T, Kumar H, Jang MH, Kawai T, Tani T, Takeuchi O, Akira S.

J Immunol. 2009 Aug 15;183(4):2522-8. doi: 10.4049/jimmunol.0901500.

5.

A discrete population of IFN λ-expressing BDCA3hi dendritic cells is present in human thymus.

Martínez VG, Canseco NM, Hidalgo L, Valencia J, Entrena A, Fernández-Sevilla LM, Hernández-López C, Sacedón R, Vicente A, Varas A.

Immunol Cell Biol. 2015 Aug;93(7):673-8. doi: 10.1038/icb.2015.22.

PMID:
25753268
6.

Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens.

Jongbloed SL, Kassianos AJ, McDonald KJ, Clark GJ, Ju X, Angel CE, Chen CJ, Dunbar PR, Wadley RB, Jeet V, Vulink AJ, Hart DN, Radford KJ.

J Exp Med. 2010 Jun 7;207(6):1247-60. doi: 10.1084/jem.20092140.

7.

Cholera toxin inhibits IL-12 production and CD8alpha+ dendritic cell differentiation by cAMP-mediated inhibition of IRF8 function.

la Sala A, He J, Laricchia-Robbio L, Gorini S, Iwasaki A, Braun M, Yap GS, Sher A, Ozato K, Kelsall B.

J Exp Med. 2009 Jun 8;206(6):1227-35. doi: 10.1084/jem.20080912. Erratum in: J Exp Med. 2009 Jul 6;206(7):1635.

8.

Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells.

Poulin LF, Salio M, Griessinger E, Anjos-Afonso F, Craciun L, Chen JL, Keller AM, Joffre O, Zelenay S, Nye E, Le Moine A, Faure F, Donckier V, Sancho D, Cerundolo V, Bonnet D, Reis e Sousa C.

J Exp Med. 2010 Jun 7;207(6):1261-71. doi: 10.1084/jem.20092618.

9.

BDCA3 expression is associated with high IFN-λ production by CD34(+)-derived dendritic cells generated in the presence of GM-CSF, IL-4, and/or TGF-β.

van der Aa E, van de Laar L, Janssen HL, van Montfoort N, Woltman AM.

Eur J Immunol. 2015 May;45(5):1471-81. doi: 10.1002/eji.201444802.

10.

Gene expression and antiviral activity of alpha/beta interferons and interleukin-29 in virus-infected human myeloid dendritic cells.

Osterlund P, Veckman V, Sirén J, Klucher KM, Hiscott J, Matikainen S, Julkunen I.

J Virol. 2005 Aug;79(15):9608-17.

12.

A new subset of CD103+CD8alpha+ dendritic cells in the small intestine expresses TLR3, TLR7, and TLR9 and induces Th1 response and CTL activity.

Fujimoto K, Karuppuchamy T, Takemura N, Shimohigoshi M, Machida T, Haseda Y, Aoshi T, Ishii KJ, Akira S, Uematsu S.

J Immunol. 2011 Jun 1;186(11):6287-95. doi: 10.4049/jimmunol.1004036.

13.

CD141⁺ myeloid dendritic cells are enriched in healthy human liver.

Kelly A, Fahey R, Fletcher JM, Keogh C, Carroll AG, Siddachari R, Geoghegan J, Hegarty JE, Ryan EJ, O'Farrelly C.

J Hepatol. 2014 Jan;60(1):135-42. doi: 10.1016/j.jhep.2013.08.007.

PMID:
23968887
14.

Immunoadjuvant effects of polyadenylic:polyuridylic acids through TLR3 and TLR7.

Sugiyama T, Hoshino K, Saito M, Yano T, Sasaki I, Yamazaki C, Akira S, Kaisho T.

Int Immunol. 2008 Jan;20(1):1-9.

15.

A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells.

Gautier G, Humbert M, Deauvieau F, Scuiller M, Hiscott J, Bates EE, Trinchieri G, Caux C, Garrone P.

J Exp Med. 2005 May 2;201(9):1435-46.

16.

IFN-alpha skews monocyte differentiation into Toll-like receptor 7-expressing dendritic cells with potent functional activities.

Mohty M, Vialle-Castellano A, Nunes JA, Isnardon D, Olive D, Gaugler B.

J Immunol. 2003 Oct 1;171(7):3385-93.

17.

Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8alpha+ conventional dendritic cells.

Edelson BT, KC W, Juang R, Kohyama M, Benoit LA, Klekotka PA, Moon C, Albring JC, Ise W, Michael DG, Bhattacharya D, Stappenbeck TS, Holtzman MJ, Sung SS, Murphy TL, Hildner K, Murphy KM.

J Exp Med. 2010 Apr 12;207(4):823-36. doi: 10.1084/jem.20091627.

18.

TLR3-mediated IFN-β gene induction is negatively regulated by the TLR adaptor MyD88 adaptor-like.

Siednienko J, Halle A, Nagpal K, Golenbock DT, Miggin SM.

Eur J Immunol. 2010 Nov;40(11):3150-60. doi: 10.1002/eji.201040547.

19.

Astrocyte indoleamine 2,3-dioxygenase is induced by the TLR3 ligand poly(I:C): mechanism of induction and role in antiviral response.

Suh HS, Zhao ML, Rivieccio M, Choi S, Connolly E, Zhao Y, Takikawa O, Brosnan CF, Lee SC.

J Virol. 2007 Sep;81(18):9838-50.

20.

Combined TLR stimulation with Pam3Cys and Poly I: C enhances Flt3-ligand dendritic cell activation for tumor immunotherapy.

Lim SN, Kuhn S, Hyde E, Ronchese F.

J Immunother. 2012 Nov-Dec;35(9):670-9. doi: 10.1097/CJI.0b013e318270e135.

PMID:
23090076
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