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Items: 1 to 20 of 95

1.

Biological reactive intermediates (BRIs) formed from botanical dietary supplements.

Dietz BM, Bolton JL.

Chem Biol Interact. 2011 Jun 30;192(1-2):72-80. doi: 10.1016/j.cbi.2010.10.007. Epub 2010 Oct 21. Review.

2.

Screening botanical extracts for quinoid metabolites.

Johnson BM, Bolton JL, van Breemen RB.

Chem Res Toxicol. 2001 Nov;14(11):1546-51.

PMID:
11712913
3.

Updates on chemical and biological research on botanical ingredients in dietary supplements.

Pawar RS, Tamta H, Ma J, Krynitsky AJ, Grundel E, Wamer WG, Rader JI.

Anal Bioanal Chem. 2013 May;405(13):4373-84. doi: 10.1007/s00216-012-6691-2. Epub 2013 Jan 16. Review.

PMID:
23322353
4.

Herbal bioactivation, molecular targets and the toxicity relevance.

Chen XW, Serag ES, Sneed KB, Zhou SF.

Chem Biol Interact. 2011 Jul 15;192(3):161-76. doi: 10.1016/j.cbi.2011.03.016. Epub 2011 Apr 1. Review.

PMID:
21459083
5.

Angelica sinensis and its alkylphthalides induce the detoxification enzyme NAD(P)H: quinone oxidoreductase 1 by alkylating Keap1.

Dietz BM, Liu D, Hagos GK, Yao P, Schinkovitz A, Pro SM, Deng S, Farnsworth NR, Pauli GF, van Breemen RB, Bolton JL.

Chem Res Toxicol. 2008 Oct;21(10):1939-48. doi: 10.1021/tx8001274. Epub 2008 Sep 23.

6.

Xanthohumol isolated from Humulus lupulus Inhibits menadione-induced DNA damage through induction of quinone reductase.

Dietz BM, Kang YH, Liu G, Eggler AL, Yao P, Chadwick LR, Pauli GF, Farnsworth NR, Mesecar AD, van Breemen RB, Bolton JL.

Chem Res Toxicol. 2005 Aug;18(8):1296-305.

PMID:
16097803
7.

Metabolic activation of herbal and dietary constituents and its clinical and toxicological implications: an update.

Zhou SF, Xue CC, Yu XQ, Wang G.

Curr Drug Metab. 2007 Aug;8(6):526-53. Review.

PMID:
17691916
8.

Analysis of flavonoid phytoestrogens in botanical and ephedra-containing dietary supplements.

Grippo AA, Capps K, Rougeau B, Gurley BJ.

Ann Pharmacother. 2007 Sep;41(9):1375-82. Epub 2007 Aug 14.

PMID:
17698891
9.

Modulation of Estrogen Chemical Carcinogenesis by Botanical Supplements used for Postmenopausal Women's Health.

Snelten CS, Dietz B, Bolton JL.

Drug Discov Today Dis Mech. 2012 Jun 1;9(1). pii: 47-54.

10.

Development of Safe and Effective Botanical Dietary Supplements.

van Breemen RB.

J Med Chem. 2015 Nov 12;58(21):8360-72. doi: 10.1021/acs.jmedchem.5b00417. Epub 2015 Jul 21.

11.

Many drugs and phytochemicals can be activated to biological reactive intermediates.

Johnson WW.

Curr Drug Metab. 2008 May;9(4):344-51. Review.

PMID:
18473753
12.

In vitro formation of quinoid metabolites of the dietary supplement Cimicifuga racemosa (black cohosh).

Johnson BM, van Breemen RB.

Chem Res Toxicol. 2003 Jul;16(7):838-46.

PMID:
12870886
13.

Biological and chemical standardization of a hop (Humulus lupulus) botanical dietary supplement.

Krause E, Yuan Y, Hajirahimkhan A, Dong H, Dietz BM, Nikolic D, Pauli GF, Bolton JL, van Breemen RB.

Biomed Chromatogr. 2014 Jun;28(6):729-34. doi: 10.1002/bmc.3177.

14.

Ensuring the safety of botanical dietary supplements.

van Breemen RB, Fong HH, Farnsworth NR.

Am J Clin Nutr. 2008 Feb;87(2):509S-13S.

15.

Screening method for the discovery of potential cancer chemoprevention agents based on mass spectrometric detection of alkylated Keap1.

Liu G, Eggler AL, Dietz BM, Mesecar AD, Bolton JL, Pezzuto JM, van Breemen RB.

Anal Chem. 2005 Oct 1;77(19):6407-14.

PMID:
16194107
16.

Menopause: a review of botanical dietary supplements.

Low Dog T.

Am J Med. 2005 Dec 19;118 Suppl 12B:98-108. Review.

PMID:
16414334
17.

The relevance of higher plants in lead compound discovery programs.

Kinghorn AD, Pan L, Fletcher JN, Chai H.

J Nat Prod. 2011 Jun 24;74(6):1539-55. doi: 10.1021/np200391c. Epub 2011 Jun 8. Review.

18.

Implementing a "quality by design" approach to assure the safety and integrity of botanical dietary supplements.

Khan IA, Smillie T.

J Nat Prod. 2012 Sep 28;75(9):1665-73. Epub 2012 Aug 31. Review.

PMID:
22938174
19.
20.

A natural history of botanical therapeutics.

Schmidt B, Ribnicky DM, Poulev A, Logendra S, Cefalu WT, Raskin I.

Metabolism. 2008 Jul;57(7 Suppl 1):S3-9. doi: 10.1016/j.metabol.2008.03.001. Review.

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