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Acetylation modulates prolactin receptor dimerization.

Ma L, Gao JS, Guan Y, Shi X, Zhang H, Ayrapetov MK, Zhang Z, Xu L, Hyun YM, Kim M, Zhuang S, Chin YE.

Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19314-9. doi: 10.1073/pnas.1010253107. Epub 2010 Oct 20.


Two wrongs can make a right: dimers of prolactin and growth hormone receptor antagonists behave as agonists.

Langenheim JF, Tan D, Walker AM, Chen WY.

Mol Endocrinol. 2006 Mar;20(3):661-74. Epub 2005 Nov 3.


Ligand-independent dimerization of the human prolactin receptor isoforms: functional implications.

Gadd SL, Clevenger CV.

Mol Endocrinol. 2006 Nov;20(11):2734-46. Epub 2006 Jul 13.


The role of prolactin receptor in GH signaling in breast cancer cells.

Xu J, Sun D, Jiang J, Deng L, Zhang Y, Yu H, Bahl D, Langenheim JF, Chen WY, Fuchs SY, Frank SJ.

Mol Endocrinol. 2013 Feb;27(2):266-79. doi: 10.1210/me.2012-1297. Epub 2012 Nov 28.


Structural characterization of the stem-stem dimerization interface between prolactin receptor chains complexed with the natural hormone.

van Agthoven J, Zhang C, Tallet E, Raynal B, Hoos S, Baron B, England P, Goffin V, Broutin I.

J Mol Biol. 2010 Nov 19;404(1):112-26. doi: 10.1016/j.jmb.2010.09.036. Epub 2010 Sep 25.


Subdomain 2, Not the Transmembrane Domain, Determines the Dimerization Partner of Growth Hormone Receptor and Prolactin Receptor.

Liu Y, Jiang J, Lepik B, Zhang Y, Zinn KR, Frank SJ.

Endocrinology. 2017 Oct 1;158(10):3235-3248. doi: 10.1210/en.2017-00469.


Growth hormone signaling in human T47D breast cancer cells: potential role for a growth hormone receptor-prolactin receptor complex.

Xu J, Zhang Y, Berry PA, Jiang J, Lobie PE, Langenheim JF, Chen WY, Frank SJ.

Mol Endocrinol. 2011 Apr;25(4):597-610. doi: 10.1210/me.2010-0255. Epub 2011 Feb 10.


Development of a novel ligand that activates JAK2/STAT5 signaling through a heterodimer of prolactin receptor and growth hormone receptor.

Langenheim JF, Chen WY.

J Recept Signal Transduct Res. 2009;29(2):107-12. doi: 10.1080/10799890902845252.


Crystal structure of an affinity-matured prolactin complexed to its dimerized receptor reveals the topology of hormone binding site 2.

Broutin I, Jomain JB, Tallet E, van Agthoven J, Raynal B, Hoos S, Kragelund BB, Kelly PA, Ducruix A, England P, Goffin V.

J Biol Chem. 2010 Mar 12;285(11):8422-33. doi: 10.1074/jbc.M109.089128. Epub 2010 Jan 6.


Identification of a gain-of-function mutation of the prolactin receptor in women with benign breast tumors.

Bogorad RL, Courtillot C, Mestayer C, Bernichtein S, Harutyunyan L, Jomain JB, Bachelot A, Kuttenn F, Kelly PA, Goffin V, Touraine P; Benign Breast Diseases Study Group.

Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14533-8. doi: 10.1073/pnas.0800685105. Epub 2008 Sep 8.


The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression.

Wang W, Pan K, Chen Y, Huang C, Zhang X.

Nucleic Acids Res. 2012 Feb;40(3):981-95. doi: 10.1093/nar/gkr818. Epub 2011 Oct 3.


CIS1 interacts with the Y532 of the prolactin receptor and suppresses prolactin-dependent STAT5 activation.

Endo T, Sasaki A, Minoguchi M, Joo A, Yoshimura A.

J Biochem. 2003 Jan;133(1):109-13.


CAML promotes prolactin-dependent proliferation of breast cancer cells by facilitating prolactin receptor signaling pathways.

Lim JH, Kim TY, Kim WH, Park JW.

Breast Cancer Res Treat. 2011 Nov;130(1):19-27. doi: 10.1007/s10549-010-1274-4. Epub 2010 Dec 3.


Prolactin (PRL) and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice.

Bole-Feysot C, Goffin V, Edery M, Binart N, Kelly PA.

Endocr Rev. 1998 Jun;19(3):225-68. Review.


Internalization of prolactin receptor and prolactin in transfected cells does not involve nuclear translocation.

Perrot-Applanat M, Gualillo O, Buteau H, Edery M, Kelly PA.

J Cell Sci. 1997 May;110 ( Pt 9):1123-32.


Functional characterization of the intermediate isoform of the human prolactin receptor.

Kline JB, Roehrs H, Clevenger CV.

J Biol Chem. 1999 Dec 10;274(50):35461-8.

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