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In utero and lactational exposure to a complex mixture of polychlorinated biphenyls: toxicity in pups dependent on the Cyp1a2 and Ahr genotypes.

Curran CP, Vorhees CV, Williams MT, Genter MB, Miller ML, Nebert DW.

Toxicol Sci. 2011 Jan;119(1):189-208. doi: 10.1093/toxsci/kfq314. Epub 2010 Oct 20.


In utero and lactational exposure to PCBs in mice: adult offspring show altered learning and memory depending on Cyp1a2 and Ahr genotypes.

Curran CP, Nebert DW, Genter MB, Patel KV, Schaefer TL, Skelton MR, Williams MT, Vorhees CV.

Environ Health Perspect. 2011 Sep;119(9):1286-93. doi: 10.1289/ehp.1002965. Epub 2011 May 13.


Ahrd Cyp1a2(-/-) mice show increased susceptibility to PCB-induced developmental neurotoxicity.

Curran CP, Altenhofen E, Ashworth A, Brown A, Kamau-Cheggeh C, Curran M, Evans A, Floyd R, Fowler J, Garber H, Hays B, Kraemer S, Lang A, Mynhier A, Samuels A, Strohmaier C.

Neurotoxicology. 2012 Dec;33(6):1436-42. doi: 10.1016/j.neuro.2012.08.005. Epub 2012 Aug 23.


Genetic differences in lethality of newborn mice treated in utero with coplanar versus non-coplanar hexabromobiphenyl.

Curran CP, Miller KA, Dalton TP, Vorhees CV, Miller ML, Shertzer HG, Nebert DW.

Toxicol Sci. 2006 Feb;89(2):454-64. Epub 2005 Nov 16.


Responsiveness of hepatic and cerebral cytochrome P450 in rat offspring prenatally and lactationally exposed to a reconstituted PCB mixture.

Bonfanti P, Comelli F, Assi L, Casati L, Colciago A, Villa S, Santagostino A, Costa B, Colombo A.

Environ Toxicol. 2014 Aug;29(8):856-66. doi: 10.1002/tox.21812. Epub 2012 Sep 15.


Arylhydrocarbon receptor-dependent induction of liver and lung cytochromes P450 1A1, 1A2, and 1B1 by polycyclic aromatic hydrocarbons and polychlorinated biphenyls in genetically engineered C57BL/6J mice.

Shimada T, Inoue K, Suzuki Y, Kawai T, Azuma E, Nakajima T, Shindo M, Kurose K, Sugie A, Yamagishi Y, Fujii-Kuriyama Y, Hashimoto M.

Carcinogenesis. 2002 Jul;23(7):1199-207.


Altered thyroxin and retinoid metabolic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin in aryl hydrocarbon receptor-null mice.

Nishimura N, Yonemoto J, Miyabara Y, Fujii-Kuriyama Y, Tohyama C.

Arch Toxicol. 2005 May;79(5):260-7. Epub 2004 Nov 17.


In vitro and in vivo induction of cytochrome P450 by coplanar polychlorinated/brominated biphenyls (Co-PXBs) providing high TEQ in mother's milk in Japan.

Kakutani H, Aozasa O, Mizuno A, Akiyama E, Nakao T, Ohta S.

Toxicology. 2014 Oct 3;324:68-75. doi: 10.1016/j.tox.2014.07.008. Epub 2014 Jul 26.


Polychlorinated biphenyls affect gene expression in the rabbit preimplantation embryo.

Kietz S, Fischer B.

Mol Reprod Dev. 2003 Mar;64(3):251-60.


Proinflammatory properties of coplanar PCBs: in vitro and in vivo evidence.

Hennig B, Meerarani P, Slim R, Toborek M, Daugherty A, Silverstone AE, Robertson LW.

Toxicol Appl Pharmacol. 2002 Jun 15;181(3):174-83.

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