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Items: 1 to 20 of 90

1.

The INSIG2 rs7566605 polymorphism is not associated with body mass index and breast cancer risk.

Campa D, Hüsing A, McKay JD, Sinilnikova O, Vogel U, Tjønneland A, Overvad K, Stegger J, Clavel-Chapelon F, Chabbert-Buffet N, Fagherazzi G, Trichopoulou A, Zylis D, Oustoglou E, Rohrmann S, Teucher B, Fisher E, Boeing H, Masala G, Krogh V, Sacerdote C, Panico S, Tumino R, Onland-Moret NC, van Gils CH, Bueno-de-Mesquita HB, Lund E, Chirlaque MD, Sala N, Quirós JR, Ardanaz E, Amiano P, Molina-Montes E, Hallmans G, Lenner P, Travis RC, Key TJ, Wareham N, Khaw KT, Rinaldi S, Slimani N, Chajes V, Siddiq A, Riboli E, Kaaks R, Canzian F.

BMC Cancer. 2010 Oct 18;10:563. doi: 10.1186/1471-2407-10-563.

2.

The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts.

Bressler J, Fornage M, Hanis CL, Kao WH, Lewis CE, McPherson R, Dent R, Mosley TH, Pennacchio LA, Boerwinkle E.

BMC Med Genet. 2009 Jun 12;10:56. doi: 10.1186/1471-2350-10-56.

3.

Genetic associations of the INSIG2 rs7566605 polymorphism with obesity-related metabolic traits in Malaysian Malays.

Apalasamy YD, Moy FM, Rampal S, Bulgiba A, Mohamed Z.

Genet Mol Res. 2014 Jul 4;13(3):4904-10. doi: 10.4238/2014.July.4.4.

4.

Lack of association between a common polymorphism near the INSIG2 gene and BMI, myocardial infarction, and cardiovascular risk factors.

Wiedmann S, Neureuther K, Stark K, Reinhard W, Kallmünzer B, Baessler A, Fischer M, Linsel-Nitschke P, Erdmann J, Schunkert H, Hengstenberg C.

Obesity (Silver Spring). 2009 Jul;17(7):1390-5. doi: 10.1038/oby.2008.669. Epub 2009 Feb 5.

5.

Controversial association results for INSIG2 on body mass index may be explained by interactions with age and with MC4R.

Malzahn D, Müller-Nurasyid M, Heid IM, Wichmann HE; KORA study group, Bickeböller H.

Eur J Hum Genet. 2014 Oct;22(10):1217-24. doi: 10.1038/ejhg.2014.3. Epub 2014 Feb 12.

6.

INSIG2 gene polymorphism is associated with increased subcutaneous fat in women and poor response to resistance training in men.

Orkunoglu-Suer FE, Gordish-Dressman H, Clarkson PM, Thompson PD, Angelopoulos TJ, Gordon PM, Moyna NM, Pescatello LS, Visich PS, Zoeller RF, Harmon B, Seip RL, Hoffman EP, Devaney JM.

BMC Med Genet. 2008 Dec 23;9:117. doi: 10.1186/1471-2350-9-117.

7.

Potential association of INSIG2 rs7566605 polymorphism with body weight in a Chinese subpopulation.

Yang L, Wu Y, Li H, Yu Z, Li X, Liu Y, Lin X, Chen Y.

Eur J Hum Genet. 2008 Jun;16(6):759-61. doi: 10.1038/ejhg.2008.8. Epub 2008 Feb 13.

8.

A tagging SNP in INSIG2 is associated with obesity-related phenotypes among Samoans.

Deka R, Xu L, Pal P, Toelupe PT, Laumoli TS, Xi H, Zhang G, Weeks DE, McGarvey ST.

BMC Med Genet. 2009 Dec 22;10:143. doi: 10.1186/1471-2350-10-143.

9.

INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese.

Hotta K, Nakamura M, Nakata Y, Matsuo T, Kamohara S, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Masuzaki H, Yoneda M, Nakajima A, Miyazaki S, Tokunaga K, Kawamoto M, Funahashi T, Hamaguchi K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Nakao K, Sakata T, Matsuzawa Y, Tanaka K, Kamatani N, Nakamura Y.

J Hum Genet. 2008;53(9):857-62. doi: 10.1007/s10038-008-0317-8. Epub 2008 Jul 10.

10.

INSIG2 polymorphism is neither associated with BMI nor with phenotypes of lipoprotein metabolism.

Boes E, Kollerits B, Heid IM, Hunt SC, Pichler M, Paulweber B, Coassin S, Adams TD, Hopkins PN, Lingenhel A, Wagner SA, Kronenberg F.

Obesity (Silver Spring). 2008 Apr;16(4):827-33. doi: 10.1038/oby.2007.132. Epub 2008 Jan 31.

11.

Absence of association between the INSIG2 gene polymorphism (rs7566605) and obesity in the European Youth Heart Study (EYHS).

Vimaleswaran KS, Franks PW, Brage S, Sardinha LB, Andersen LB, Wareham NJ, Ekelund U, Loos RJ.

Obesity (Silver Spring). 2009 Jul;17(7):1453-7. doi: 10.1038/oby.2008.650. Epub 2009 Feb 5.

12.
13.

The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts.

Lyon HN, Emilsson V, Hinney A, Heid IM, Lasky-Su J, Zhu X, Thorleifsson G, Gunnarsdottir S, Walters GB, Thorsteinsdottir U, Kong A, Gulcher J, Nguyen TT, Scherag A, Pfeufer A, Meitinger T, Brönner G, Rief W, Soto-Quiros ME, Avila L, Klanderman B, Raby BA, Silverman EK, Weiss ST, Laird N, Ding X, Groop L, Tuomi T, Isomaa B, Bengtsson K, Butler JL, Cooper RS, Fox CS, O'Donnell CJ, Vollmert C, Celedón JC, Wichmann HE, Hebebrand J, Stefansson K, Lange C, Hirschhorn JN.

PLoS Genet. 2007 Apr 27;3(4):e61. Epub 2007 Mar 7.

14.

INSIG2 promoter variant, obesity markers and lipid parameters - No association in a large Slavonic Caucasian population sample.

Hubácek JA, Kuthanová L, Bohuslavová R, Adámková V, Lánská V, Meitinger T, Pfeufer A.

Folia Biol (Praha). 2010;56(3):131-4.

15.

Non-replication of genome-wide based associations between common variants in INSIG2 and PFKP and obesity in studies of 18,014 Danes.

Andreasen CH, Mogensen MS, Borch-Johnsen K, Sandbaek A, Lauritzen T, Sørensen TI, Hansen L, Almind K, Jørgensen T, Pedersen O, Hansen T.

PLoS One. 2008 Aug 6;3(8):e2872. doi: 10.1371/journal.pone.0002872.

16.

A common polymorphism is associated with body mass index in Uyghur population.

Zhang J, Lin R, Wang F, Lu M, Lin RY, Wang SZ, Wen H, Jin L, Wang XF.

Diabetes Res Clin Pract. 2008 Aug;81(2):e11-3. doi: 10.1016/j.diabres.2008.03.022. Epub 2008 Jun 2.

PMID:
18514965
17.

Association of the common genetic variant upstream of INSIG2 gene with obesity related phenotypes in Chinese children and adolescents.

Wang HJ, Zhang H, Zhang SW, Pan YP, Ma J.

Biomed Environ Sci. 2008 Dec;21(6):528-36. doi: 10.1016/S0895-3988(09)60013-1.

PMID:
19263810
18.

The single nucleotide polymorphism upstream of insulin-induced gene 2 ( INSIG2) is associated with the prevalence of hypercholesterolaemia, but not with obesity, in Japanese American women.

Oki K, Yamane K, Kamei N, Asao T, Awaya T, Kohno N.

Br J Nutr. 2009 Feb;101(3):322-7. doi: 10.1017/S0007114508006557. Epub 2008 Jun 23.

PMID:
18570692
19.

Association of INSIG2 polymorphism with overweight and LDL in children.

Kaulfers AM, Deka R, Dolan L, Martin LJ.

PLoS One. 2015 Jan 21;10(1):e0116340. doi: 10.1371/journal.pone.0116340. eCollection 2015.

20.

INSIG2 SNPs associated with obesity and glucose homeostasis traits in Hispanics: the IRAS Family Study.

Talbert ME, Langefeld CD, Ziegler JT, Haffner SM, Norris JM, Bowden DW.

Obesity (Silver Spring). 2009 Aug;17(8):1554-62. doi: 10.1038/oby.2009.94. Epub 2009 Apr 9.

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