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Items: 1 to 20 of 225

1.

Development of sporadic microsatellite instability in colorectal tumors involves hypermethylation at methylated-in-tumor loci in adenoma.

de Maat MF, Narita N, Benard A, Yoshimura T, Kuo C, Tollenaar RA, de Miranda NF, Turner RR, van de Velde CJ, Morreau H, Hoon DS.

Am J Pathol. 2010 Nov;177(5):2347-56. doi: 10.2353/ajpath.2010.091103. Epub 2010 Oct 15.

2.

Distinct BRAF (V600E) and KRAS mutations in high microsatellite instability sporadic colorectal cancer in African Americans.

Kumar K, Brim H, Giardiello F, Smoot DT, Nouraie M, Lee EL, Ashktorab H.

Clin Cancer Res. 2009 Feb 15;15(4):1155-61. doi: 10.1158/1078-0432.CCR-08-1029. Epub 2009 Feb 3.

3.

Annexin A10 expression correlates with serrated pathway features in colorectal carcinoma with microsatellite instability.

Kim JH, Rhee YY, Kim KJ, Cho NY, Lee HS, Kang GH.

APMIS. 2014 Dec;122(12):1187-95. doi: 10.1111/apm.12284. Epub 2014 Jun 7.

PMID:
24909058
4.

IGF2 differentially methylated region hypomethylation in relation to pathological and molecular features of serrated lesions.

Naito T, Nosho K, Ito M, Igarashi H, Mitsuhashi K, Yoshii S, Aoki H, Nomura M, Sukawa Y, Yamamoto E, Adachi Y, Takahashi H, Hosokawa M, Fujita M, Takenouchi T, Maruyama R, Suzuki H, Baba Y, Imai K, Yamamoto H, Ogino S, Shinomura Y.

World J Gastroenterol. 2014 Aug 7;20(29):10050-61. doi: 10.3748/wjg.v20.i29.10050.

5.

Prevalence of somatic mutl homolog 1 promoter hypermethylation in Lynch syndrome colorectal cancer.

Moreira L, Muñoz J, Cuatrecasas M, Quintanilla I, Leoz ML, Carballal S, Ocaña T, López-Cerón M, Pellise M, Castellví-Bel S, Jover R, Andreu M, Carracedo A, Xicola RM, Llor X, Boland CR, Goel A, Castells A, Balaguer F; Gastrointestinal Oncology Group of the Spanish Gastroenterological Association.

Cancer. 2015 May 1;121(9):1395-404. doi: 10.1002/cncr.29190. Epub 2014 Dec 29.

6.

Sporadic colon cancer: mismatch repair immunohistochemistry and microsatellite instability in Omani subjects.

Ashktorab H, Brim H, Al-Riyami M, Date A, Al-Mawaly K, Kashoub M, Al-Mjeni R, Smoot DT, Al-Moundhri M, Al-Hashemi S, Ganguly SS, Raeburn S.

Dig Dis Sci. 2008 Oct;53(10):2723-31. doi: 10.1007/s10620-007-0189-3. Epub 2008 Feb 26.

PMID:
18299982
7.

Methylation tolerance due to an O6-methylguanine DNA methyltransferase (MGMT) field defect in the colonic mucosa: an initiating step in the development of mismatch repair-deficient colorectal cancers.

Svrcek M, Buhard O, Colas C, Coulet F, Dumont S, Massaoudi I, Lamri A, Hamelin R, Cosnes J, Oliveira C, Seruca R, Gaub MP, Legrain M, Collura A, Lascols O, Tiret E, Fléjou JF, Duval A.

Gut. 2010 Nov;59(11):1516-26. doi: 10.1136/gut.2009.194787.

PMID:
20947886
8.

Microsatellite instability-low colorectal cancer acquires a KRAS mutation during the progression from Dukes' A to Dukes' B.

Asaka S, Arai Y, Nishimura Y, Yamaguchi K, Ishikubo T, Yatsuoka T, Tanaka Y, Akagi K.

Carcinogenesis. 2009 Mar;30(3):494-9. doi: 10.1093/carcin/bgp017. Epub 2009 Jan 15.

PMID:
19147861
9.

Distinction of hereditary nonpolyposis colorectal cancer and sporadic microsatellite-unstable colorectal cancer through quantification of MLH1 methylation by real-time PCR.

Bettstetter M, Dechant S, Ruemmele P, Grabowski M, Keller G, Holinski-Feder E, Hartmann A, Hofstaedter F, Dietmaier W.

Clin Cancer Res. 2007 Jun 1;13(11):3221-8.

10.

Possible role of Cdx2 in the serrated pathway of colorectal cancer characterized by BRAF mutation, high-level CpG Island methylator phenotype and mismatch repair-deficiency.

Dawson H, Galván JA, Helbling M, Muller DE, Karamitopoulou E, Koelzer VH, Economou M, Hammer C, Lugli A, Zlobec I.

Int J Cancer. 2014 May 15;134(10):2342-51. doi: 10.1002/ijc.28564. Epub 2013 Nov 13.

11.

Microsatellite instability, MLH1 promoter methylation, and BRAF mutation analysis in sporadic colorectal cancers of different ethnic groups in Israel.

Vilkin A, Niv Y, Nagasaka T, Morgenstern S, Levi Z, Fireman Z, Fuerst F, Goel A, Boland CR.

Cancer. 2009 Feb 15;115(4):760-9. doi: 10.1002/cncr.24019.

12.

Microsatellite instability, mismatch repair deficiency, and BRAF mutation in treatment-resistant germ cell tumors.

Honecker F, Wermann H, Mayer F, Gillis AJ, Stoop H, van Gurp RJ, Oechsle K, Steyerberg E, Hartmann JT, Dinjens WN, Oosterhuis JW, Bokemeyer C, Looijenga LH.

J Clin Oncol. 2009 May 1;27(13):2129-36. doi: 10.1200/JCO.2008.18.8623. Epub 2009 Mar 16.

PMID:
19289622
13.

Somatic molecular changes and histo-pathological features of colorectal cancer in Tunisia.

Aissi S, Buisine MP, Zerimech F, Kourda N, Moussa A, Manai M, Porchet N.

World J Gastroenterol. 2013 Aug 28;19(32):5286-94. doi: 10.3748/wjg.v19.i32.5286.

14.

A high degree of LINE-1 hypomethylation is a unique feature of early-onset colorectal cancer.

Antelo M, Balaguer F, Shia J, Shen Y, Hur K, Moreira L, Cuatrecasas M, Bujanda L, Giraldez MD, Takahashi M, Cabanne A, Barugel ME, Arnold M, Roca EL, Andreu M, Castellvi-Bel S, Llor X, Jover R, Castells A, Boland CR, Goel A.

PLoS One. 2012;7(9):e45357. doi: 10.1371/journal.pone.0045357. Epub 2012 Sep 25.

15.

Early onset MSI-H colon cancer with MLH1 promoter methylation, is there a genetic predisposition?

van Roon EH, van Puijenbroek M, Middeldorp A, van Eijk R, de Meijer EJ, Erasmus D, Wouters KA, van Engeland M, Oosting J, Hes FJ, Tops CM, van Wezel T, Boer JM, Morreau H.

BMC Cancer. 2010 May 5;10:180. doi: 10.1186/1471-2407-10-180.

16.

Molecular characterization of endometrial cancer: a correlative study assessing microsatellite instability, MLH1 hypermethylation, DNA mismatch repair protein expression, and PTEN, PIK3CA, KRAS, and BRAF mutation analysis.

Peterson LM, Kipp BR, Halling KC, Kerr SE, Smith DI, Distad TJ, Clayton AC, Medeiros F.

Int J Gynecol Pathol. 2012 May;31(3):195-205. doi: 10.1097/PGP.0b013e318231fc51.

PMID:
22498935
17.

Aberrant DNA methylation in hereditary nonpolyposis colorectal cancer without mismatch repair deficiency.

Goel A, Xicola RM, Nguyen TP, Doyle BJ, Sohn VR, Bandipalliam P, Rozek LS, Reyes J, Cordero C, Balaguer F, Castells A, Jover R, Andreu M, Syngal S, Boland CR, Llor X.

Gastroenterology. 2010 May;138(5):1854-62. doi: 10.1053/j.gastro.2010.01.035. Epub 2010 Jan 25.

18.

Molecular profile and copy number analysis of sporadic colorectal cancer in Taiwan.

Lin CH, Lin JK, Chang SC, Chang YH, Chang HM, Liu JH, Li LH, Chen YT, Tsai SF, Chen WS.

J Biomed Sci. 2011 Jun 7;18:36. doi: 10.1186/1423-0127-18-36.

19.

Molecular genetic analysis of 103 sporadic colorectal tumours in Czech patients.

Vasovcak P, Pavlikova K, Sedlacek Z, Skapa P, Kouda M, Hoch J, Krepelova A.

PLoS One. 2011;6(8):e24114. doi: 10.1371/journal.pone.0024114. Epub 2011 Aug 25.

20.

Role of the BRAF mutations in the microsatellite instability genetic pathway in sporadic colorectal cancer.

Maestro ML, Vidaurreta M, Sanz-Casla MT, Rafael S, Veganzones S, Martínez A, Aguilera C, Herranz MD, Cerdán J, Arroyo M.

Ann Surg Oncol. 2007 Mar;14(3):1229-36. Epub 2006 Dec 31.

PMID:
17195912

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