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Items: 1 to 20 of 91

1.

Sun-induced nonsynonymous p53 mutations are extensively accumulated and tolerated in normal appearing human skin.

Ståhl PL, Stranneheim H, Asplund A, Berglund L, Pontén F, Lundeberg J.

J Invest Dermatol. 2011 Feb;131(2):504-8. doi: 10.1038/jid.2010.302. Epub 2010 Oct 14.

3.

Clones of normal keratinocytes and a variety of simultaneously present epidermal neoplastic lesions contain a multitude of p53 gene mutations in a xeroderma pigmentosum patient.

Williams C, Pontén F, Ahmadian A, Ren ZP, Ling G, Rollman O, Ljung A, Jaspers NG, Uhlén M, Lundeberg J, Pontén J.

Cancer Res. 1998 Jun 1;58(11):2449-55.

4.

Enhanced epidermal ultraviolet responses in chronically sun-exposed skin are dependent on previous sun exposure.

Wassberg C, Bäckvall H, Diffey B, Pontén F, Berne B.

Acta Derm Venereol. 2003;83(4):254-61.

PMID:
12926795
5.

UV-radiation-specific p53 mutation frequency in normal skin as a predictor of risk of basal cell carcinoma.

Ouhtit A, Nakazawa H, Armstrong BK, Kricker A, Tan E, Yamasaki H, English DR.

J Natl Cancer Inst. 1998 Apr 1;90(7):523-31.

PMID:
9539248
6.

UV-induced ablation of the epidermal basal layer including p53-mutant clones resets UV carcinogenesis showing squamous cell carcinomas to originate from interfollicular epidermis.

Rebel HG, Bodmann CA, van de Glind GC, de Gruijl FR.

Carcinogenesis. 2012 Mar;33(3):714-20. doi: 10.1093/carcin/bgs004. Epub 2012 Jan 6.

PMID:
22227037
7.

UV-induced DNA damage and mutations in Hupki (human p53 knock-in) mice recapitulate p53 hotspot alterations in sun-exposed human skin.

Luo JL, Tong WM, Yoon JH, Hergenhahn M, Koomagi R, Yang Q, Galendo D, Pfeifer GP, Wang ZQ, Hollstein M.

Cancer Res. 2001 Nov 15;61(22):8158-63.

8.

Mutation spectra of epidermal p53 clones adjacent to basal cell carcinoma and squamous cell carcinoma.

Bäckvall H, Strömberg S, Gustafsson A, Asplund A, Sivertsson A, Lundeberg J, Ponten F.

Exp Dermatol. 2004 Oct;13(10):643-50.

PMID:
15447725
9.

Decreased p53 expression in chronically sun-exposed human skin after topical photoprotection.

Berne B, Pontén J, Pontén F.

Photodermatol Photoimmunol Photomed. 1998 Oct-Dec;14(5-6):148-53.

PMID:
9826884
10.

Mutations in the TP53 gene in human malignant melanomas derived from sun-exposed skin and unexposed mucosal membranes.

Ragnarsson-Olding BK, Karsberg S, Platz A, Ringborg UK.

Melanoma Res. 2002 Oct;12(5):453-63.

PMID:
12394187
11.

Relationship of p53 mutations to epidermal cell proliferation and apoptosis in human UV-induced skin carcinogenesis.

Einspahr JG, Alberts DS, Warneke JA, Bozzo P, Basye J, Grogan TM, Nelson MA, Bowden GT.

Neoplasia. 1999 Nov;1(5):468-75.

12.

Similar UV responses are seen in a skin organ culture as in human skin in vivo.

Bäckvall H, Wassberg C, Berne B, Ponten F.

Exp Dermatol. 2002 Aug;11(4):349-56.

PMID:
12190944
13.

Frequent p53 accumulation in the chronically sun-exposed epidermis and clonal expansion of p53 mutant cells in the epidermis adjacent to basal cell carcinoma.

Urano Y, Asano T, Yoshimoto K, Iwahana H, Kubo Y, Kato S, Sasaki S, Takeuchi N, Uchida N, Nakanishi H, et al.

J Invest Dermatol. 1995 Jun;104(6):928-32.

14.

Persistent p53 mutations in single cells from normal human skin.

Ling G, Persson A, Berne B, Uhlén M, Lundeberg J, Ponten F.

Am J Pathol. 2001 Oct;159(4):1247-53.

15.
16.

Expression of p53 protein in actinic keratosis, adjacent, normal-appearing, and non-sun-exposed human skin.

Einspahr J, Alberts DS, Aickin M, Welch K, Bozzo P, Grogan T, Nelson M.

Cancer Epidemiol Biomarkers Prev. 1997 Aug;6(8):583-7.

17.

Accumulated p53 protein and UVA protection level of sunscreens.

Seité S, Moyal D, Verdier MP, Hourseau C, Fourtanier A.

Photodermatol Photoimmunol Photomed. 2000 Feb;16(1):3-9.

PMID:
10721857
18.

p53 protects against skin cancer induction by UV-B radiation.

Jiang W, Ananthaswamy HN, Muller HK, Kripke ML.

Oncogene. 1999 Jul 22;18(29):4247-53.

19.

Ultraviolet A within sunlight induces mutations in the epidermal basal layer of engineered human skin.

Huang XX, Bernerd F, Halliday GM.

Am J Pathol. 2009 Apr;174(4):1534-43. doi: 10.2353/ajpath.2009.080318. Epub 2009 Mar 5.

20.

Influences of p53 deficiency on the apoptotic response, DNA damage removal and mutagenesis in UVB-exposed mouse skin.

Ikehata H, Okuyama R, Ogawa E, Nakamura S, Usami A, Mori T, Tanaka K, Aiba S, Ono T.

Mutagenesis. 2010 Jul;25(4):397-405. doi: 10.1093/mutage/geq019. Epub 2010 May 12.

PMID:
20462948

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