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Items: 1 to 20 of 106

1.

Protein kinase A regulates caspase-1 via Ets-1 in bone stromal cell-derived lesions: a link between cyclic AMP and pro-inflammatory pathways in osteoblast progenitors.

Almeida MQ, Tsang KM, Cheadle C, Watkins T, Grivel JC, Nesterova M, Goldbach-Mansky R, Stratakis CA.

Hum Mol Genet. 2011 Jan 1;20(1):165-75. doi: 10.1093/hmg/ddq455. Epub 2010 Oct 11.

2.

Enhanced chondrogenesis of induced pluripotent stem cells from patients with neonatal-onset multisystem inflammatory disease occurs via the caspase 1-independent cAMP/protein kinase A/CREB pathway.

Yokoyama K, Ikeya M, Umeda K, Oda H, Nodomi S, Nasu A, Matsumoto Y, Izawa K, Horigome K, Kusaka T, Tanaka T, Saito MK, Yasumi T, Nishikomori R, Ohara O, Nakayama N, Nakahata T, Heike T, Toguchida J.

Arthritis Rheumatol. 2015 Jan;67(1):302-14. doi: 10.1002/art.38912.

3.

Prostaglandin E2 Inhibits NLRP3 Inflammasome Activation through EP4 Receptor and Intracellular Cyclic AMP in Human Macrophages.

Sokolowska M, Chen LY, Liu Y, Martinez-Anton A, Qi HY, Logun C, Alsaaty S, Park YH, Kastner DL, Chae JJ, Shelhamer JH.

J Immunol. 2015 Jun 1;194(11):5472-87. doi: 10.4049/jimmunol.1401343. Epub 2015 Apr 27.

4.

PKA/CREB signaling triggers initiation of endothelial and hematopoietic cell differentiation via Etv2 induction.

Yamamizu K, Matsunaga T, Katayama S, Kataoka H, Takayama N, Eto K, Nishikawa S, Yamashita JK.

Stem Cells. 2012 Apr;30(4):687-96. doi: 10.1002/stem.1041.

5.

NLRP3 inflammasome inhibition is disrupted in a group of auto-inflammatory disease CAPS mutations.

Mortimer L, Moreau F, MacDonald JA, Chadee K.

Nat Immunol. 2016 Oct;17(10):1176-86. doi: 10.1038/ni.3538. Epub 2016 Aug 22.

PMID:
27548431
6.

PGE2 induces IL-1beta gene expression in mouse osteoblasts through a cAMP-PKA signaling pathway.

Park YG, Kang SK, Noh SH, Park KK, Chang YC, Lee YC, Kim CH.

Int Immunopharmacol. 2004 Jun;4(6):779-89.

PMID:
15135319
7.

PGE2 potentiates tonicity-induced COX-2 expression in renal medullary cells in a positive feedback loop involving EP2-cAMP-PKA signaling.

Steinert D, K├╝per C, Bartels H, Beck FX, Neuhofer W.

Am J Physiol Cell Physiol. 2009 Jan;296(1):C75-87. doi: 10.1152/ajpcell.00024.2008. Epub 2008 Nov 12.

8.

PGE2 induces the gene expression of bone matrix metalloproteinase-1 in mouse osteoblasts by cAMP-PKA signaling pathway.

Kim CH, Park YG, Noh SH, Kim YK.

Int J Biochem Cell Biol. 2005 Feb;37(2):375-85.

PMID:
15474982
9.

Parathyroid hormone induces mitogen-activated kinase phosphatase 1 in murine osteoblasts primarily through cAMP-protein kinase A signaling.

Aghaloo TL, Pirih FQ, Shi A, Bezouglaia O, Tetradis S.

J Periodontol. 2006 Jan;77(1):21-30.

PMID:
16579699
10.

Loading-related regulation of transcription factor EGR2/Krox-20 in bone cells is ERK1/2 protein-mediated and prostaglandin, Wnt signaling pathway-, and insulin-like growth factor-I axis-dependent.

Zaman G, Sunters A, Galea GL, Javaheri B, Saxon LK, Moustafa A, Armstrong VJ, Price JS, Lanyon LE.

J Biol Chem. 2012 Feb 3;287(6):3946-62. doi: 10.1074/jbc.M111.252742. Epub 2011 Nov 2.

11.

Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA- and EP1/Ca2+-mediated mechanism in the human pancreatic carcinoma cell line PANC-1.

Chang HH, Young SH, Sinnett-Smith J, Chou CE, Moro A, Hertzer KM, Hines OJ, Rozengurt E, Eibl G.

Am J Physiol Cell Physiol. 2015 Nov 15;309(10):C639-49. doi: 10.1152/ajpcell.00417.2014. Epub 2015 Aug 26.

12.

Bone Abnormalities in Mice with Protein Kinase A (PKA) Defects Reveal a Role of Cyclic AMP Signaling in Bone Stromal Cell-Dependent Tumor Development.

Liu S, Shapiro JM, Saloustros E, Stratakis CA.

Horm Metab Res. 2016 Nov;48(11):714-725. Epub 2016 Oct 11. Review.

PMID:
27728928
13.

Prostaglandin E2 induces stromal cell-derived factor-1 expression in prostate stromal cells by activating protein kinase A and transcription factor Sp1.

Peng Y, Shi J, Du X, Wang L, Klocker H, Mo L, Mo Z, Zhang J.

Int J Biochem Cell Biol. 2013 Mar;45(3):521-30. doi: 10.1016/j.biocel.2012.11.017. Epub 2012 Dec 11.

PMID:
23246486
14.

cAMP/PKA signaling defects in tumors: genetics and tissue-specific pluripotential cell-derived lesions in human and mouse.

Stratakis CA.

Mol Cell Endocrinol. 2013 May 22;371(1-2):208-20. doi: 10.1016/j.mce.2013.01.015. Epub 2013 Feb 26. Review.

15.

The small molecule PKA-specific cyclic AMP analogue as an inducer of osteoblast-like cells differentiation and mineralization.

Lo KW, Kan HM, Ashe KM, Laurencin CT.

J Tissue Eng Regen Med. 2012 Jan;6(1):40-8. doi: 10.1002/term.395. Epub 2011 Feb 10.

16.

PTHrP signaling targets cyclin D1 and induces osteoblastic cell growth arrest.

Datta NS, Chen C, Berry JE, McCauley LK.

J Bone Miner Res. 2005 Jun;20(6):1051-64. Epub 2005 Jan 18.

17.

Prostaglandin E2 induces interleukin-6 expression in human chondrocytes via cAMP/protein kinase A- and phosphatidylinositol 3-kinase-dependent NF-kappaB activation.

Wang P, Zhu F, Konstantopoulos K.

Am J Physiol Cell Physiol. 2010 Jun;298(6):C1445-56. doi: 10.1152/ajpcell.00508.2009. Epub 2010 Mar 24.

18.

Prostaglandin E2 stimulates osteoclast-like cell formation and bone-resorbing activity via osteoblasts: role of cAMP-dependent protein kinase.

Kaji H, Sugimoto T, Kanatani M, Fukase M, Kumegawa M, Chihara K.

J Bone Miner Res. 1996 Jan;11(1):62-71.

PMID:
8770698
20.

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