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Items: 1 to 20 of 114

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1.

Glucose stimulates human beta cell replication in vivo in islets transplanted into NOD-severe combined immunodeficiency (SCID) mice.

Levitt HE, Cyphert TJ, Pascoe JL, Hollern DA, Abraham N, Lundell RJ, Rosa T, Romano LC, Zou B, O'Donnell CP, Stewart AF, Garcia-Ocaña A, Alonso LC.

Diabetologia. 2011 Mar;54(3):572-82. doi: 10.1007/s00125-010-1919-1. Epub 2010 Oct 9.

2.

Human beta cell proliferation by glucose--a complex scenario.

Tiedge M.

Diabetologia. 2011 Mar;54(3):477-9. doi: 10.1007/s00125-010-2015-2. Epub 2010 Dec 21. No abstract available.

PMID:
21174074
3.

Neural crest stem cells increase beta cell proliferation and improve islet function in co-transplanted murine pancreatic islets.

Olerud J, Kanaykina N, Vasylovska S, King D, Sandberg M, Jansson L, Kozlova EN.

Diabetologia. 2009 Dec;52(12):2594-601. doi: 10.1007/s00125-009-1544-z. Epub 2009 Oct 13. Erratum in: Diabetologia. 2010 Feb;53(2):396. Vasilovska, S [corrected to Vasylovska, S].

PMID:
19823803
4.

A new immunodeficient hyperglycaemic mouse model based on the Ins2Akita mutation for analyses of human islet and beta stem and progenitor cell function.

Pearson T, Shultz LD, Lief J, Burzenski L, Gott B, Chase T, Foreman O, Rossini AA, Bottino R, Trucco M, Greiner DL.

Diabetologia. 2008 Aug;51(8):1449-56. doi: 10.1007/s00125-008-1057-1. Epub 2008 Jun 19.

5.

Amyloid formation results in recurrence of hyperglycaemia following transplantation of human IAPP transgenic mouse islets.

Udayasankar J, Kodama K, Hull RL, Zraika S, Aston-Mourney K, Subramanian SL, Tong J, Faulenbach MV, Vidal J, Kahn SE.

Diabetologia. 2009 Jan;52(1):145-53. doi: 10.1007/s00125-008-1185-7. Epub 2008 Nov 11.

6.

Transplantation of insulin-producing cells differentiated from human periosteum-derived progenitor cells ameliorate hyperglycemia in diabetic mice.

Dao LT, Park EY, Lim SM, Choi YS, Jung HS, Jun HS.

Transplantation. 2014 Nov 27;98(10):1040-7. doi: 10.1097/TP.0000000000000388.

PMID:
25208321
7.

Stimulating β-cell replication and improving islet graft function by AR231453, A GPR119 agonist.

Gao J, Tian L, Weng G, O'Brien TD, Luo J, Guo Z.

Transplant Proc. 2011 Nov;43(9):3217-20. doi: 10.1016/j.transproceed.2011.10.021.

PMID:
22099761
8.

Comparison of exendin-4 on beta-cell replication in mouse and human islet grafts.

Tian L, Gao J, Weng G, Yi H, Tian B, O'Brien TD, Guo Z.

Transpl Int. 2011 Aug;24(8):856-64. doi: 10.1111/j.1432-2277.2011.01275.x. Epub 2011 Jun 1.

9.

Pancreatic insulin-producing cells differentiated from human embryonic stem cells correct hyperglycemia in SCID/NOD mice, an animal model of diabetes.

Hua XF, Wang YW, Tang YX, Yu SQ, Jin SH, Meng XM, Li HF, Liu FJ, Sun Q, Wang HY, Li JY.

PLoS One. 2014 Jul 10;9(7):e102198. doi: 10.1371/journal.pone.0102198. eCollection 2014.

10.
11.

Caspase-3 gene silencing for inhibiting apoptosis in insulinoma cells and human islets.

Cheng G, Zhu L, Mahato RI.

Mol Pharm. 2008 Nov-Dec;5(6):1093-102. doi: 10.1021/mp800093f.

PMID:
18828606
12.

Improved function and proliferation of adult human beta cells engrafted in diabetic immunodeficient NOD-scid IL2rγ(null) mice treated with alogliptin.

Jurczyk A, Diiorio P, Brostowin D, Leehy L, Yang C, Urano F, Harlan DM, Shultz LD, Greiner DL, Bortell R.

Diabetes Metab Syndr Obes. 2013 Dec 13;6:493-9. doi: 10.2147/DMSO.S53154. eCollection 2013.

13.

Function, mass, and replication of porcine and rat islets transplanted into diabetic nude mice.

Davalli AM, Ogawa Y, Scaglia L, Wu YJ, Hollister J, Bonner-Weir S, Weir GC.

Diabetes. 1995 Jan;44(1):104-11.

PMID:
7813803
15.

Influence of diabetes on the loss of beta cell differentiation after islet transplantation in rats.

Laybutt DR, Hawkins YC, Lock J, Lebet J, Sharma A, Bonner-Weir S, Weir GC.

Diabetologia. 2007 Oct;50(10):2117-25. Epub 2007 Jul 20.

PMID:
17641871
16.

XIAP inhibition of β-cell apoptosis reduces the number of islets required to restore euglycemia in a syngeneic islet transplantation model.

Plesner A, Soukhatcheva G, Korneluk RG, Verchere CB.

Islets. 2010 Jan-Feb;2(1):18-23. doi: 10.4161/isl.2.1.9997.

PMID:
21099289
17.
18.

Activation of GPR119 Stimulates Human β-Cell Replication and Neogenesis in Humanized Mice with Functional Human Islets.

Ansarullah, Free C, Christopherson J, Chen Q, Gao J, Liu C, Naji A, Rabinovitch A, Guo Z.

J Diabetes Res. 2016;2016:1620821. doi: 10.1155/2016/1620821. Epub 2016 Jun 16.

19.

Encapsulated piscine (tilapia) islets for diabetes therapy: studies in diabetic NOD and NOD-SCID mice.

Safley SA, Cui H, Cauffiel SM, Xu BY, Wright JR Jr, Weber CJ.

Xenotransplantation. 2014 Mar-Apr;21(2):127-39. doi: 10.1111/xen.12086. Epub 2014 Mar 17.

PMID:
24635017
20.

Gene transfer of constitutively active Akt markedly improves human islet transplant outcomes in diabetic severe combined immunodeficient mice.

Rao P, Roccisana J, Takane KK, Bottino R, Zhao A, Trucco M, García-Ocaña A.

Diabetes. 2005 Jun;54(6):1664-75.

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