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Aryl hydrocarbon receptor nuclear translocator in hepatocytes is required for aryl hydrocarbon receptor-mediated adaptive and toxic responses in liver.

Nukaya M, Walisser JA, Moran SM, Kennedy GD, Bradfield CA.

Toxicol Sci. 2010 Dec;118(2):554-63. doi: 10.1093/toxsci/kfq305. Epub 2010 Oct 8.


Hypoxia perturbs aryl hydrocarbon receptor signaling and CYP1A1 expression induced by PCB 126 in human skin and liver-derived cell lines.

Vorrink SU, Severson PL, Kulak MV, Futscher BW, Domann FE.

Toxicol Appl Pharmacol. 2014 Feb 1;274(3):408-16. doi: 10.1016/j.taap.2013.12.002. Epub 2013 Dec 16.


Aryl hydrocarbon receptor (AHR) and AHR nuclear translocator (ARNT) expression in Baikal seal (Pusa sibirica) and association with 2,3,7,8-TCDD toxic equivalents and CYP1 expression levels.

Kim EY, Iwata H, Suda T, Tanabe S, Amano M, Miyazaki N, Petrov EA.

Comp Biochem Physiol C Toxicol Pharmacol. 2005 Jul;141(3):281-91.


Patent ductus venosus and dioxin resistance in mice harboring a hypomorphic Arnt allele.

Walisser JA, Bunger MK, Glover E, Harstad EB, Bradfield CA.

J Biol Chem. 2004 Apr 16;279(16):16326-31. Epub 2004 Feb 5.


Gestational exposure of Ahr and Arnt hypomorphs to dioxin rescues vascular development.

Walisser JA, Bunger MK, Glover E, Bradfield CA.

Proc Natl Acad Sci U S A. 2004 Nov 23;101(47):16677-82. Epub 2004 Nov 15.


Dioxin toxicity in vivo results from an increase in the dioxin-independent transcriptional activity of the aryl hydrocarbon receptor.

Céspedes MA, Galindo MI, Couso JP.

PLoS One. 2010 Nov 8;5(11):e15382. doi: 10.1371/journal.pone.0015382.


Knockout of the aryl hydrocarbon receptor results in distinct hepatic and renal phenotypes in rats and mice.

Harrill JA, Hukkanen RR, Lawson M, Martin G, Gilger B, Soldatow V, Lecluyse EL, Budinsky RA, Rowlands JC, Thomas RS.

Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18. doi: 10.1016/j.taap.2013.06.024. Epub 2013 Jul 13.


Abnormal liver development and resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity in mice carrying a mutation in the DNA-binding domain of the aryl hydrocarbon receptor.

Bunger MK, Glover E, Moran SM, Walisser JA, Lahvis GP, Hsu EL, Bradfield CA.

Toxicol Sci. 2008 Nov;106(1):83-92. doi: 10.1093/toxsci/kfn149. Epub 2008 Jul 27.


Distinct roles for aryl hydrocarbon receptor nuclear translocator and ah receptor in estrogen-mediated signaling in human cancer cell lines.

Labrecque MP, Takhar MK, Hollingshead BD, Prefontaine GG, Perdew GH, Beischlag TV.

PLoS One. 2012;7(1):e29545. doi: 10.1371/journal.pone.0029545. Epub 2012 Jan 3.


Resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity and abnormal liver development in mice carrying a mutation in the nuclear localization sequence of the aryl hydrocarbon receptor.

Bunger MK, Moran SM, Glover E, Thomae TL, Lahvis GP, Lin BC, Bradfield CA.

J Biol Chem. 2003 May 16;278(20):17767-74. Epub 2003 Mar 5.


Aryl hydrocarbon receptor expression and activity in cerebellar granule neuroblasts: implications for development and dioxin neurotoxicity.

Williamson MA, Gasiewicz TA, Opanashuk LA.

Toxicol Sci. 2005 Feb;83(2):340-8. Epub 2004 Nov 10.


Identification of functional aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocator in murine splenocytes.

Williams CE, Crawford RB, Holsapple MP, Kaminski NE.

Biochem Pharmacol. 1996 Sep 13;52(5):771-80.


Recruitment of the NCoA/SRC-1/p160 family of transcriptional coactivators by the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator complex.

Beischlag TV, Wang S, Rose DW, Torchia J, Reisz-Porszasz S, Muhammad K, Nelson WE, Probst MR, Rosenfeld MG, Hankinson O.

Mol Cell Biol. 2002 Jun;22(12):4319-33.


Novel roles for AhR and ARNT in the regulation of alcohol dehydrogenases in human hepatic cells.

Attignon EA, Leblanc AF, Le-Grand B, Duval C, Aggerbeck M, Rouach H, Blanc EB.

Arch Toxicol. 2017 Jan;91(1):313-324. doi: 10.1007/s00204-016-1700-4. Epub 2016 Apr 8.


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