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Items: 1 to 20 of 201

1.

Dermal uptake and excretion of 14C-toluene diisocyante (TDI) and 14C-methylene diphenyl diisocyanate (MDI) in male rats. Clinical signs and histopathology following dermal exposure of male rats to TDI.

Hoffmann HD, Leibold E, Ehnes C, Fabian E, Landsiedel R, Gamer A, Poole A.

Toxicol Lett. 2010 Dec 15;199(3):364-71. doi: 10.1016/j.toxlet.2010.09.021.

PMID:
20933064
2.

Route-dependent comparative metabolism of [14C]toluene 2,4-diisocyanate and [14C]toluene 2,4-diamine in Fischer 344 rats.

Timchalk C, Smith FA, Bartels MJ.

Toxicol Appl Pharmacol. 1994 Feb;124(2):181-90.

PMID:
8122263
3.

Carcinogenic risk of toluene diisocyanate and 4,4'-methylenediphenyl diisocyanate: epidemiological and experimental evidence.

Bolognesi C, Baur X, Marczynski B, Norppa H, Sepai O, Sabbioni G.

Crit Rev Toxicol. 2001 Nov;31(6):737-72. Review.

PMID:
11763481
4.

Micronuclei, hemoglobin adducts and respiratory tract irritation in mice after inhalation of toluene diisocyanate (TDI) and 4,4'-methylenediphenyl diisocyanate (MDI).

Lindberg HK, Korpi A, Santonen T, Säkkinen K, Järvelä M, Tornaeus J, Ahonen N, Järventaus H, Pasanen AL, Rosenberg C, Norppa H.

Mutat Res. 2011 Jul 14;723(1):1-10. doi: 10.1016/j.mrgentox.2011.03.009.

PMID:
21453781
6.

Distribution and reactivity of inhaled 14C-labeled toluene diisocyanate (TDI) in rats.

Kennedy AL, Wilson TR, Stock MF, Alarie Y, Brown WE.

Arch Toxicol. 1994;68(7):434-43.

PMID:
7979960
7.

The carcinogenic activity of commercial grade toluene diisocyanate in rats and mice in relation to the metabolism of the 2,4- and 2,6-TDI isomers.

Dieter MP, Boorman GA, Jameson CW, Matthews HB, Huff JE.

Toxicol Ind Health. 1990 Dec;6(6):599-621.

PMID:
1965872
9.

Respiratory response to toluene diisocyanate depends on prior frequency and concentration of dermal sensitization in mice.

Vanoirbeek JA, Tarkowski M, Ceuppens JL, Verbeken EK, Nemery B, Hoet PH.

Toxicol Sci. 2004 Aug;80(2):310-21.

10.

Rats repeatedly exposed to toluene diisocyanate exhibit immune reactivity against methyl isocyanate-protein conjugates.

Svensson-Elfsmark L, Koch BL, Gustafsson A, Bucht A.

Int Arch Allergy Immunol. 2009;150(3):229-36. doi: 10.1159/000222675.

PMID:
19494520
11.

Uptake and distribution of 14C during and following inhalation exposure to radioactive toluene diisocyanate.

Kennedy AL, Stock MF, Alarie Y, Brown WE.

Toxicol Appl Pharmacol. 1989 Sep 1;100(2):280-92.

PMID:
2551072
12.

Absorption, distribution, metabolism and excretion of an inhalation dose of [14C] 4,4'-methylenediphenyl diisocyanate in the male rat.

Gledhill A, Wake A, Hext P, Leibold E, Shiotsuka R.

Xenobiotica. 2005 Mar;35(3):273-92.

PMID:
16019951
13.

Concentration-dependent elicitation of dermal sensitization in guinea pigs treated with 2,4-toluene diisocyanate.

Koschier FJ, Burden EJ, Brunkhorst CS, Friedman MA.

Toxicol Appl Pharmacol. 1983 Mar 15;67(3):401-7.

PMID:
6302947
15.

Toluene diisocyanate: an assessment of carcinogenic risk following oral and inhalation exposure.

Doe JE, Hoffmann HD.

Toxicol Ind Health. 1995 Jan-Feb;11(1):13-32. Review.

PMID:
7652749
17.
18.

Chronic inhalation toxicity and carcinogenicity study of respirable polymeric methylene diphenyl diisocyanate (polymeric MDI) aerosol in rats.

Reuzel PG, Arts JH, Lomax LG, Kuijpers MH, Kuper CF, Gembardt C, Feron VJ, Löser E.

Fundam Appl Toxicol. 1994 Feb;22(2):195-210.

PMID:
8005372
19.

Isocyanate-induced asthma: results of inhalation tests with TDI, MDI and methacholine.

Vogelmeier C, Baur X, Fruhmann G.

Int Arch Occup Environ Health. 1991;63(1):9-13.

PMID:
1649802
20.

Toluene diisocyanate and methylene diphenyl diisocyanate: asthmatic response and cross-reactivity in a mouse model.

Pollaris L, Devos F, De Vooght V, Seys S, Nemery B, Hoet PH, Vanoirbeek JA.

Arch Toxicol. 2016 Jul;90(7):1709-17. doi: 10.1007/s00204-015-1606-6.

PMID:
26468151
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