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Items: 1 to 20 of 53

1.

Short-chain 3-hydroxyacyl-CoA dehydrogenase is a negative regulator of insulin secretion in response to fuel and non-fuel stimuli in INS832/13 β-cells.

Pepin E, Guay C, Delghingaro-Augusto V, Joly E, Madiraju SR, Prentki M.

J Diabetes. 2010 Sep;2(3):157-67. doi: 10.1111/j.1753-0407.2010.00076.x.

2.

Specificity in beta cell expression of L-3-hydroxyacyl-CoA dehydrogenase, short chain, and potential role in down-regulating insulin release.

Martens GA, Vervoort A, Van de Casteele M, Stangé G, Hellemans K, Van Thi HV, Schuit F, Pipeleers D.

J Biol Chem. 2007 Jul 20;282(29):21134-44. Epub 2007 May 9.

3.

Hyperinsulinism in short-chain L-3-hydroxyacyl-CoA dehydrogenase deficiency reveals the importance of beta-oxidation in insulin secretion.

Clayton PT, Eaton S, Aynsley-Green A, Edginton M, Hussain K, Krywawych S, Datta V, Malingre HE, Berger R, van den Berg IE.

J Clin Invest. 2001 Aug;108(3):457-65.

4.

Short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency associated with hyperinsulinism: a novel glucose-fatty acid cycle?

Eaton S, Chatziandreou I, Krywawych S, Pen S, Clayton PT, Hussain K.

Biochem Soc Trans. 2003 Dec;31(Pt 6):1137-9. Review.

PMID:
14641012
5.

The HADHSC gene encoding short-chain L-3-hydroxyacyl-CoA dehydrogenase (SCHAD) and type 2 diabetes susceptibility: the DAMAGE study.

van Hove EC, Hansen T, Dekker JM, Reiling E, Nijpels G, Jørgensen T, Borch-Johnsen K, Hamid YH, Heine RJ, Pedersen O, Maassen JA, 't Hart LM.

Diabetes. 2006 Nov;55(11):3193-6.

6.

Functional genomics of the beta-cell: short-chain 3-hydroxyacyl-coenzyme A dehydrogenase regulates insulin secretion independent of K+ currents.

Hardy OT, Hohmeier HE, Becker TC, Manduchi E, Doliba NM, Gupta RK, White P, Stoeckert CJ Jr, Matschinsky FM, Newgard CB, Kaestner KH.

Mol Endocrinol. 2007 Mar;21(3):765-73. Epub 2006 Dec 21.

PMID:
17185391
7.

Structural organization of the human short-chain L-3-hydroxyacyl-CoA dehydrogenase gene.

Vredendaal PJ, van den Berg IE, Stroobants AK, van der A DL, Malingré HE, Berger R.

Mamm Genome. 1998 Sep;9(9):763-8.

PMID:
9716664
8.

Mechanism of hyperinsulinism in short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency involves activation of glutamate dehydrogenase.

Li C, Chen P, Palladino A, Narayan S, Russell LK, Sayed S, Xiong G, Chen J, Stokes D, Butt YM, Jones PM, Collins HW, Cohen NA, Cohen AS, Nissim I, Smith TJ, Strauss AW, Matschinsky FM, Bennett MJ, Stanley CA.

J Biol Chem. 2010 Oct 8;285(41):31806-18. doi: 10.1074/jbc.M110.123638. Epub 2010 Jul 29.

9.

Familial hyperinsulinemic hypoglycemia caused by a defect in the SCHAD enzyme of mitochondrial fatty acid oxidation.

Molven A, Matre GE, Duran M, Wanders RJ, Rishaug U, Njølstad PR, Jellum E, Søvik O.

Diabetes. 2004 Jan;53(1):221-7.

10.

Mechanisms of amino acid-stimulated insulin secretion in congenital hyperinsulinism.

Zhang T, Li C.

Acta Biochim Biophys Sin (Shanghai). 2013 Jan;45(1):36-43. doi: 10.1093/abbs/gms107. Epub 2012 Dec 4. Review.

12.

Palmitate activates AMP-activated protein kinase and regulates insulin secretion from beta cells.

Wang X, Zhou L, Li G, Luo T, Gu Y, Qian L, Fu X, Li F, Li J, Luo M.

Biochem Biophys Res Commun. 2007 Jan 12;352(2):463-8. Epub 2006 Nov 16.

PMID:
17118340
13.

Regulation of hormone-sensitive lipase in islets.

Shen WJ, Liang Y, Wang J, Harada K, Patel S, Michie SA, Osuga J, Ishibashi S, Kraemer FB.

Diabetes Res Clin Pract. 2007 Jan;75(1):14-26. Epub 2006 Jun 9.

PMID:
16765472
15.

Peroxisomal D-hydroxyacyl-CoA dehydrogenase deficiency: resolution of the enzyme defect and its molecular basis in bifunctional protein deficiency.

van Grunsven EG, van Berkel E, Ijlst L, Vreken P, de Klerk JB, Adamski J, Lemonde H, Clayton PT, Cuebas DA, Wanders RJ.

Proc Natl Acad Sci U S A. 1998 Mar 3;95(5):2128-33.

16.

Insulin/phosphoinositide 3-kinase pathway accelerates the glucose-induced first-phase insulin secretion through TrpV2 recruitment in pancreatic β-cells.

Aoyagi K, Ohara-Imaizumi M, Nishiwaki C, Nakamichi Y, Nagamatsu S.

Biochem J. 2010 Dec 1;432(2):375-86. doi: 10.1042/BJ20100864.

PMID:
20854263
17.

Down-regulation of Kir6.2 affects calcium influx and insulin secretion in HIT-T15 cells.

Chen F, Zheng D, Xu Y, Luo Y, Li H, Yu K, Song Y, Zhong W, Ji Y.

J Pediatr Endocrinol Metab. 2010 Jul;23(7):709-17.

PMID:
20857843
18.

D-3-hydroxyacyl-CoA dehydratase/D-3-hydroxyacyl-CoA dehydrogenase bifunctional protein deficiency: a newly identified peroxisomal disorder.

Suzuki Y, Jiang LL, Souri M, Miyazawa S, Fukuda S, Zhang Z, Une M, Shimozawa N, Kondo N, Orii T, Hashimoto T.

Am J Hum Genet. 1997 Nov;61(5):1153-62.

19.

Lack of correlation between fatty acid oxidation disorders and haemolysis, elevated liver enzymes, low platelets (HELLP) syndrome?

Holub M, Bodamer OA, Item C, Mühl A, Pollak A, Stöckler-Ipsiroglu S.

Acta Paediatr. 2005 Jan;94(1):48-52.

PMID:
15858960
20.

Hyperinsulinism of infancy associated with a novel splice site mutation in the SCHAD gene.

Hussain K, Clayton PT, Krywawych S, Chatziandreou I, Mills P, Ginbey DW, Geboers AJ, Berger R, van den Berg IE, Eaton S.

J Pediatr. 2005 May;146(5):706-8.

PMID:
15870679

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