Similar articles for PMID: 20922525

Year	Number of Results
1981	1
1991	1
1993	2
1994	1
1996	1
1999	1
2002	1
2003	1
2004	4
2005	14
2006	7
2007	7
2008	7
2009	10
2010	10
2011	14
2012	12
2013	8
2014	11
2015	8
2017	6
2018	4
2019	2
2020	1
2022	3
2024	0

1

Hydralazine and magnesium valproate as epigenetic treatment for myelodysplastic syndrome. Preliminary results of a phase-II trial.

Candelaria M, Herrera A, Labardini J, González-Fierro A, Trejo-Becerril C, Taja-Chayeb L, Pérez-Cárdenas E, de la Cruz-Hernández E, Arias-Bofill D, Vidal S, Cervera E, Dueñas-Gonzalez A. Candelaria M, et al. Ann Hematol. 2011 Apr;90(4):379-87. doi: 10.1007/s00277-010-1090-2. Epub 2010 Oct 5. Ann Hematol. 2011. PMID: 20922525 Clinical Trial.

2

Encouraging results with the compassionate use of hydralazine/valproate (TRANSKRIP™) as epigenetic treatment for myelodysplastic syndrome (MDS).

Candelaria M, Burgos S, Ponce M, Espinoza R, Dueñas-Gonzalez A. Candelaria M, et al. Ann Hematol. 2017 Nov;96(11):1825-1832. doi: 10.1007/s00277-017-3103-x. Epub 2017 Aug 23. Ann Hematol. 2017. PMID: 28831600

3

Results of a phase 2 study of valproic acid alone or in combination with all-trans retinoic acid in 75 patients with myelodysplastic syndrome and relapsed or refractory acute myeloid leukemia.

Kuendgen A, Knipp S, Fox F, Strupp C, Hildebrandt B, Steidl C, Germing U, Haas R, Gattermann N. Kuendgen A, et al. Ann Hematol. 2005 Dec;84 Suppl 1:61-6. doi: 10.1007/s00277-005-0026-8. Ann Hematol. 2005. PMID: 16270213 Clinical Trial.

4

An epigenetic approach to the treatment of advanced MDS; the experience with the DNA demethylating agent 5-aza-2'-deoxycytidine (decitabine) in 177 patients.

Wijermans PW, Lübbert M, Verhoef G, Klimek V, Bosly A. Wijermans PW, et al. Ann Hematol. 2005 Dec;84 Suppl 1:9-17. doi: 10.1007/s00277-005-0012-1. Ann Hematol. 2005. PMID: 16211386

5

Hydralazine-valproate: a repositioned drug combination for the epigenetic therapy of cancer.

Dueñas-Gonzalez A, Coronel J, Cetina L, González-Fierro A, Chavez-Blanco A, Taja-Chayeb L. Dueñas-Gonzalez A, et al. Expert Opin Drug Metab Toxicol. 2014 Oct;10(10):1433-44. doi: 10.1517/17425255.2014.947263. Epub 2014 Aug 25. Expert Opin Drug Metab Toxicol. 2014. PMID: 25154405 Review.

6

Clinical activity and safety of the dual pathway inhibitor rigosertib for higher risk myelodysplastic syndromes following DNA methyltransferase inhibitor therapy.

Silverman LR, Greenberg P, Raza A, Olnes MJ, Holland JF, Reddy P, Maniar M, Wilhelm F. Silverman LR, et al. Hematol Oncol. 2015 Jun;33(2):57-66. doi: 10.1002/hon.2137. Epub 2014 Apr 29. Hematol Oncol. 2015. PMID: 24777753 Free article.

7

Methylation inhibitor therapy in the treatment of myelodysplastic syndrome.

Silverman LR, Mufti GJ. Silverman LR, et al. Nat Clin Pract Oncol. 2005 Dec;2 Suppl 1:S12-23. doi: 10.1038/ncponc0347. Nat Clin Pract Oncol. 2005. PMID: 16341236 Review.

8

Valproic acid at therapeutic plasma levels may increase 5-azacytidine efficacy in higher risk myelodysplastic syndromes.

Voso MT, Santini V, Finelli C, Musto P, Pogliani E, Angelucci E, Fioritoni G, Alimena G, Maurillo L, Cortelezzi A, Buccisano F, Gobbi M, Borin L, Di Tucci A, Zini G, Petti MC, Martinelli G, Fabiani E, Fazi P, Vignetti M, Piciocchi A, Liso V, Amadori S, Leone G. Voso MT, et al. Clin Cancer Res. 2009 Aug 1;15(15):5002-7. doi: 10.1158/1078-0432.CCR-09-0494. Epub 2009 Jul 28. Clin Cancer Res. 2009. PMID: 19638460 Free article. Clinical Trial.

9

Current status of epigenetic treatment in myelodysplastic syndromes.

Kuendgen A, Lübbert M. Kuendgen A, et al. Ann Hematol. 2008 Aug;87(8):601-11. doi: 10.1007/s00277-008-0477-9. Epub 2008 Apr 5. Ann Hematol. 2008. PMID: 18392623 Review.

10

DNA methyltransferase and histone deacetylase inhibitors in the treatment of myelodysplastic syndromes.

Griffiths EA, Gore SD. Griffiths EA, et al. Semin Hematol. 2008 Jan;45(1):23-30. doi: 10.1053/j.seminhematol.2007.11.007. Semin Hematol. 2008. PMID: 18179966 Free PMC article. Review.

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