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Items: 1 to 20 of 111

1.

Placental growth factor mediates aldosterone-dependent vascular injury in mice.

Jaffe IZ, Newfell BG, Aronovitz M, Mohammad NN, McGraw AP, Perreault RE, Carmeliet P, Ehsan A, Mendelsohn ME.

J Clin Invest. 2010 Nov;120(11):3891-900. doi: 10.1172/JCI40205.

2.

Aldosterone promotes vascular remodeling by direct effects on smooth muscle cell mineralocorticoid receptors.

Pruthi D, McCurley A, Aronovitz M, Galayda C, Karumanchi SA, Jaffe IZ.

Arterioscler Thromb Vasc Biol. 2014 Feb;34(2):355-64. doi: 10.1161/ATVBAHA.113.302854. Epub 2013 Dec 5.

3.

Aldosterone increases early atherosclerosis and promotes plaque inflammation through a placental growth factor-dependent mechanism.

McGraw AP, Bagley J, Chen WS, Galayda C, Nickerson H, Armani A, Caprio M, Carmeliet P, Jaffe IZ.

J Am Heart Assoc. 2013 Feb 22;2(1):e000018. doi: 10.1161/JAHA.112.000018.

4.

Functional mineralocorticoid receptors in human vascular endothelial cells regulate intercellular adhesion molecule-1 expression and promote leukocyte adhesion.

Caprio M, Newfell BG, la Sala A, Baur W, Fabbri A, Rosano G, Mendelsohn ME, Jaffe IZ.

Circ Res. 2008 Jun 6;102(11):1359-67. doi: 10.1161/CIRCRESAHA.108.174235. Epub 2008 May 8.

5.

Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1.

Autiero M, Waltenberger J, Communi D, Kranz A, Moons L, Lambrechts D, Kroll J, Plaisance S, De Mol M, Bono F, Kliche S, Fellbrich G, Ballmer-Hofer K, Maglione D, Mayr-Beyrle U, Dewerchin M, Dombrowski S, Stanimirovic D, Van Hummelen P, Dehio C, Hicklin DJ, Persico G, Herbert JM, Communi D, Shibuya M, Collen D, Conway EM, Carmeliet P.

Nat Med. 2003 Jul;9(7):936-43.

PMID:
12796773
6.

Placental growth factor deficiency is associated with impaired cerebral vascular development in mice.

Luna RL, Kay VR, Rätsep MT, Khalaj K, Bidarimath M, Peterson N, Carmeliet P, Jin A, Croy BA.

Mol Hum Reprod. 2016 Feb;22(2):130-42. doi: 10.1093/molehr/gav069. Epub 2015 Dec 7.

7.

Aldosterone regulates vascular gene transcription via oxidative stress-dependent and -independent pathways.

Newfell BG, Iyer LK, Mohammad NN, McGraw AP, Ehsan A, Rosano G, Huang PL, Mendelsohn ME, Jaffe IZ.

Arterioscler Thromb Vasc Biol. 2011 Aug;31(8):1871-80. doi: 10.1161/ATVBAHA.111.229070. Epub 2011 May 26.

9.

Aldosterone-induced oxidative stress and inflammation in the brain are mediated by the endothelial cell mineralocorticoid receptor.

Dinh QN, Young MJ, Evans MA, Drummond GR, Sobey CG, Chrissobolis S.

Brain Res. 2016 Apr 15;1637:146-53. doi: 10.1016/j.brainres.2016.02.034. Epub 2016 Feb 26.

PMID:
26923165
10.

Nuclear expression of FLT1 and its ligand PGF in FUS-DDIT3 carrying myxoid liposarcomas suggests the existence of an intracrine signaling loop.

Andersson MK, Göransson M, Olofsson A, Andersson C, Aman P.

BMC Cancer. 2010 Jun 1;10:249. doi: 10.1186/1471-2407-10-249.

11.

Mineralocorticoids in the heart and vasculature: new insights for old hormones.

Lother A, Moser M, Bode C, Feldman RD, Hein L.

Annu Rev Pharmacol Toxicol. 2015;55:289-312. doi: 10.1146/annurev-pharmtox-010814-124302. Epub 2014 Sep 10. Review.

PMID:
25251996
12.

Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II-induced cardiac, renal, and vascular injury.

Luther JM, Luo P, Wang Z, Cohen SE, Kim HS, Fogo AB, Brown NJ.

Kidney Int. 2012 Sep;82(6):643-51. doi: 10.1038/ki.2012.170. Epub 2012 May 23.

13.

Smooth muscle cell mineralocorticoid receptors: role in vascular function and contribution to cardiovascular disease.

McCurley A, McGraw A, Pruthi D, Jaffe IZ.

Pflugers Arch. 2013 Dec;465(12):1661-70. doi: 10.1007/s00424-013-1282-4. Epub 2013 May 1. Review.

14.

Mineralocorticoid receptors in vascular function and disease.

McCurley A, Jaffe IZ.

Mol Cell Endocrinol. 2012 Mar 24;350(2):256-65. doi: 10.1016/j.mce.2011.06.014. Epub 2011 Jun 24. Review.

15.

Direct role for smooth muscle cell mineralocorticoid receptors in vascular remodeling: novel mechanisms and clinical implications.

Koenig JB, Jaffe IZ.

Curr Hypertens Rep. 2014 May;16(5):427. doi: 10.1007/s11906-014-0427-y. Review.

16.

Endothelial cell mineralocorticoid receptors regulate deoxycorticosterone/salt-mediated cardiac remodeling and vascular reactivity but not blood pressure.

Rickard AJ, Morgan J, Chrissobolis S, Miller AA, Sobey CG, Young MJ.

Hypertension. 2014 May;63(5):1033-40. doi: 10.1161/HYPERTENSIONAHA.113.01803. Epub 2014 Feb 24.

17.

Atrial natriuretic peptide locally counteracts the deleterious effects of cardiomyocyte mineralocorticoid receptor activation.

Nakagawa H, Oberwinkler H, Nikolaev VO, Gaßner B, Umbenhauer S, Wagner H, Saito Y, Baba HA, Frantz S, Kuhn M.

Circ Heart Fail. 2014 Sep;7(5):814-21. doi: 10.1161/CIRCHEARTFAILURE.113.000885. Epub 2014 Jul 15.

18.

Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1.

Luttun A, Tjwa M, Moons L, Wu Y, Angelillo-Scherrer A, Liao F, Nagy JA, Hooper A, Priller J, De Klerck B, Compernolle V, Daci E, Bohlen P, Dewerchin M, Herbert JM, Fava R, Matthys P, Carmeliet G, Collen D, Dvorak HF, Hicklin DJ, Carmeliet P.

Nat Med. 2002 Aug;8(8):831-40. Epub 2002 Jul 1.

PMID:
12091877
19.

Analysis of the gene regulatory program induced by the homeobox transcription factor distal-less 3 in mouse placenta.

Han L, Dias Figueiredo M, Berghorn KA, Iwata TN, Clark-Campbell PA, Welsh IC, Wang W, O'brien TP, Lin DM, Roberson MS.

Endocrinology. 2007 Mar;148(3):1246-54. Epub 2006 Nov 16.

PMID:
17110422
20.

Mineralocorticoid receptor activation promotes vascular cell calcification.

Jaffe IZ, Tintut Y, Newfell BG, Demer LL, Mendelsohn ME.

Arterioscler Thromb Vasc Biol. 2007 Apr;27(4):799-805. Epub 2007 Jan 18.

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